Genes News and Research

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Support for chromosomal theory of cancer found in cancers' development of drug resistance

Thirty-six years into the war on cancer, scientists have not only failed to come up with a cure, but most of the newer drugs suffer from the same problems as those available in the pre-war days: serious toxicity, limited effectiveness and eventual resistance.

28 Jun 2007

New type of mouse embryonic stem cell discovered

Scientists have discovered a new type of mouse embryonic stem cell that is the closest counterpart yet to human embryonic stem (ES) cells, the National Institutes of Health (NIH) have announced.

28 Jun 2007

Scientists discover role of ataxia telangiectasia mutated protein in DNA repair

Scientists from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Cancer Institute (NCI), and Integrative Bioinformatics Inc. have made an important discovery about the role of an enzyme called ataxia telangiectasia mutated protein (ATM) in the body's ability to repair damaged DNA.

28 Jun 2007

New model for signal transduction in cells

Among the key communication systems within a cell is the Wnt signaling pathway, which regulates embryonic development and whose deregulation can also contribute to cancer development.

28 Jun 2007

15,000 children and adolescents in the United States are diagnosed with type 1 diabetes annually

Approximately 15,000 children and adolescents in the United States are diagnosed with type 1 diabetes, and about 3,700 youth are diagnosed with type 2 diabetes annually, according to estimates from a major national study called SEARCH for Diabetes in Youth.

27 Jun 2007

Gene variant increases risk for alcoholism following childhood abuse

Girls who suffered childhood sexual abuse are more likely to develop alcoholism later in life if they possess a particular variant of a gene involved in the body's response to stress, according to a new study led by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH).

27 Jun 2007

Absence of a gene called CD38 is a protective barrier to obesity

A search for the molecular clues of longevity has taken Mayo Clinic researchers down another path that could explain why some people who consume excessive calories don't gain weight.

27 Jun 2007

New genetic marker characterizes aggressiveness of cancer cells

Levels of a small non-coding RNA molecule called let-7 appear to define different stages of cancer better than some of the "classical" markers for tumor progression, researchers from the University of Chicago report in the June 25, 2007, early online edition of the Proceedings of the National Academy of Sciences.

26 Jun 2007

Scoliosis gene found

Physicians have recognized scoliosis, the abnormal curvature of the spine, since the time of Hippocrates, but its causes have remained a mystery -- until now. For the first time, researchers have discovered a gene that underlies the condition, which affects about 3 percent of all children.

26 Jun 2007