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Researchers use mRNA-loaded carriers to target genetic instructions of protein in immune cells

Delivering an effective therapeutic payload to specific target cells with few adverse effects is considered by many to be the holy grail of medical research. A new Tel Aviv University study explores a biological approach to directing nanocarriers loaded with protein "game changers" to specific cells.

30 Oct 2018

Scientists find ways to block nitration of amino acids to improve cancer immunotherapy

Immunotherapy -- harnessing T-cells to attack cancer cells in the body -- has given hope to patients who endure round after round of treatment, including chemotherapy, to little effect. For all of its promise, however, immunotherapy still benefits only a minority of patients -- a reality driving research in the field for ways to improve the relatively new approach.

30 Oct 2018

Quantum dot-based FISH method enhances cell imaging

A team of researchers from the University of Illinois at Urbana-Champaign and Mayo Clinic have engineered a new type of molecular probe that can measure and count RNA in cells and tissue without organic dyes.

30 Oct 2018

Aggressive local therapy for stage IV lung cancer patients improves progression-free survival

Adding radiation therapy or surgery to systemic therapy for stage IV lung cancer patients whose cancer has spread to a limited number of sites can extend overall survival time significantly, according to new results from a multicenter, randomized, controlled phase II study. The findings were presented last week at the 60th Annual Meeting of the American Society for Radiation Oncology

30 Oct 2018

Scientists discover cell adhesion mechanism used by mycoplasma genitalium

Researchers from the Molecular Biology Institute of Barcelona and the Institute of Biotechnology and Biomedicine have discovered the mechanism by which the bacterium Mycoplasma genitalium) adheres to human cells.

29 Oct 2018

New findings highlight importance of inflammatory component in atherosclerosis pathogenesis

One of the main characteristics of atherosclerosis is the accumulation of lipids in the intimal layer of the arterial wall.

29 Oct 2018

Researchers uncover new insights on cancer growth

Walter and Eliza Hall Institute researchers have uncovered new insights into how the normal controls on cell growth are lost in cancer cells, leading to rapid tumor expansion.

29 Oct 2018

Neuroene Therapeutics receives $1.5 million NIH grant to develop anti-seizure compound for epilepsy

Neuroene Therapeutics, a start-up company founded by mitochondrial biologist Sherine S. L. Chan, Ph.D. and medicinal chemist C. James Chou, Ph.D. of the Medical University of South Carolina, has received a $1.5 million NIH Phase II Small Business Innovation Research grant to optimize vitamin K analogues that could improve seizure control in patients with drug-resistant epilepsy.

29 Oct 2018

Insights into tumor initiation pave way for new skin cancer treatments

Researchers from VIB and KU Leuven uncovered a key vulnerability of melanoma. While studying the role of the melanoma-specific long non-coding RNA SAMMSON in tumor initiation, the researchers found that it boosts protein synthesis in different cellular compartments. Normal cells are alerted by modification in protein synthesis and react to this threat, but only if this process is altered in one compartment at the time.

29 Oct 2018

Researchers propose new contactless method for measuring blood flow in the upper limbs

The research team from Russia proposed a new contactless method for measuring blood flow in the upper limbs. The method is based on video recording of the skin surface under green light measuring the absorption of red blood cells. This helps to see how effective the circulatory system and the blood flow regulation are.

29 Oct 2018

DIACARTA introduces new QClamp assays for detection of cancer gene mutations

DIACARTA Inc., a precision molecular diagnostics company headquartered in Richmond, California, today announced that it is launching a new suite of CE-IVD marked highly sensitive hydrolysis probe based QClamp assays for detection of common cancer mutations in genes, such as KRAS, NRAS, BRAF, EGFR, PIK3CA and JAK2, using tissue biopsyand liquid biopsy samples.

29 Oct 2018

Novel bioreactor allows ultrasonic monitoring of human cartilage grown in 3D

A team of Spanish scientists has designed a bioreactor that allows to grow, in four weeks, human cartilage tissues in scaffolds generated by 3D printing.

29 Oct 2018

Scientists discover kill code in all cells that can be triggered to destroy cancer

Researchers have discovered a kill code present within every cell of the body in the form of microRNAs that can cause cancerous cells to self-destruct

29 Oct 2018

Forced expression of a natural protein reduces fat in mice by a third

In a mouse model of obesity, forced expression of the protein FGFBP3 (BP3 for short) significantly reduced the animals’ fat mass.

29 Oct 2018

Bigger brains linked to greater risk of developing tumors

It may simply be that having a big brain is itself the cause. That's what doctor and PhD candidate Even Hovig Fyllingen at the Norwegian University of Science and Technology (NTNU) has determined with his research colleagues.

29 Oct 2018

Neem Biotech granted two funding awards by Welsh Government for work in antimicrobial resistance

Neem Biotech’s work is boosted by two separate funding grants from the Welsh Government and European Regional Development Fund

From Neem Biotech 29 Oct 2018

Natural protein may offer novel therapy to reverse disorders associated with metabolic syndrome

To the great surprise of cancer researchers, a protein they investigated for its possible role in cancer turned out to be a powerful regulator of metabolism.

29 Oct 2018

Study finds kill code mechanism embedded in every cell to extinguish cancer

A kill code is embedded in every cell in the body whose function may be to cause the self-destruction of cells that become cancerous, reports a new Northwestern Medicine study. As soon as the cell's inner bodyguards sense it is mutating into cancer, they punch in the kill code to extinguish the mutating cell.

29 Oct 2018

Getting right level of leptin may help protect cardiovascular health

Like that famous bowl of porridge, when leptin levels are "just right" they help protect our cardiovascular health, scientists say.

29 Oct 2018

New approach may lead to protective vaccines for immunocompromised patients

A study led by Som Nanjappa at the University of Illinois College of Veterinary Medicine identifies a cellular target that may improve efficacy in vaccines designed to protect immunocompromised individuals from potentially deadly opportunistic infections.

26 Oct 2018

B Cell News and Research

Researchers use mRNA-loaded carriers to target genetic instructions of protein in immune cells

Scientists find ways to block nitration of amino acids to improve cancer immunotherapy

Quantum dot-based FISH method enhances cell imaging

Aggressive local therapy for stage IV lung cancer patients improves progression-free survival

Scientists discover cell adhesion mechanism used by mycoplasma genitalium

New findings highlight importance of inflammatory component in atherosclerosis pathogenesis

Researchers uncover new insights on cancer growth

Neuroene Therapeutics receives $1.5 million NIH grant to develop anti-seizure compound for epilepsy

Insights into tumor initiation pave way for new skin cancer treatments

Researchers propose new contactless method for measuring blood flow in the upper limbs

DIACARTA introduces new QClamp assays for detection of cancer gene mutations

Novel bioreactor allows ultrasonic monitoring of human cartilage grown in 3D

Scientists discover kill code in all cells that can be triggered to destroy cancer

Forced expression of a natural protein reduces fat in mice by a third

Bigger brains linked to greater risk of developing tumors

Neem Biotech granted two funding awards by Welsh Government for work in antimicrobial resistance

Natural protein may offer novel therapy to reverse disorders associated with metabolic syndrome

Study finds kill code mechanism embedded in every cell to extinguish cancer

Getting right level of leptin may help protect cardiovascular health

New approach may lead to protective vaccines for immunocompromised patients

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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