Cell Signaling News and Research

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Cell signaling is vital for cells to communicate and coordinate their activities, not just in the human body, but in all organisms. There are thousands of signaling pathways, ranging from protein homeostasis to carcinogenesis and biofilm formation.

New therapy harnesses "dancing molecules" to reverse paralysis, repair tissue after spinal cord injuries

Northwestern University investigators have developed a new injectable therapy that harnesses "dancing molecules" to reverse paralysis and repair tissue after severe spinal cord injuries.

11 Nov 2021

Plant-derived compound can be beneficial in protecting the brain against Alzheimer’s disease pathology

Fenchol, a natural compound abundant in some plants including basil, can help protect the brain against Alzheimer's disease pathology, a preclinical study led by University of South Florida Health (USF Health) researchers suggests.

5 Oct 2021

Glycerin helps calm the red itchy patches in psoriasis model

Patients with psoriasis have reported that glycerin, an inexpensive, harmless, slightly sweet liquid high on the list of ingredients in many skin lotions, is effective at combatting their psoriasis and now scientists have objective evidence to support their reports.

4 Oct 2021

SARS-CoV-2 viroporin activity impacts viral infectivity and pathogenicity

A team of researchers studied the two main viroporins of SARS-CoV-2, namely Orf3a and Envelope (E) protein, from a structural viewpoint.

29 Sep 2021

A family of proteins may be able to outwit emerging and re-emerging viruses

A family of proteins best known for their role in diminishing HIV infectivity may have the goods to outwit other emerging and re-emerging viruses, scientists have found.

15 Sep 2021

Study pinpoints an entirely new approach for treatment of biliary atresia

Biliary atresia is the largest cause of end-stage liver fibrosis in children and the main reason children need liver transplants. Despite many years of worldwide research, scientists have not yet found a way to prevent the condition.

7 Sep 2021

Research offers insights to restore blood vessel integrity during sepsis, other conditions

Sepsis occurs when the body works so hard to fight an infection that the over-activated immune system harms a patient's own tissues as collateral damage.

31 Aug 2021

Researchers reveal mechanism underlying most common cause of epileptic seizures

During fetal development, cells should migrate to the outer edge of the brain to form critical connections for information transfer and regulation in the body.

26 Aug 2021

New mathematical model can predict the optimum exercise regime for building muscle

Researchers have developed a mathematical model that can predict the optimum exercise regime for building muscle.

23 Aug 2021

Targeting a skin protein may reduce the severity of psoriasis, study reveals

Results from a Michigan Medicine study reveal that targeting a protein found in the skin may reduce the severity of psoriasis.

12 Aug 2021

Study identifies Foxo1 gene as a potential treatment target for hereditary lymphedema

A University of South Florida preclinical study unexpectedly identified the gene Foxo1 as a potential treatment target for hereditary lymphedema.

10 Aug 2021

Researchers develop new low-cost reproducible system for co-cultivation of cells

Scientists of the MIPT Cell Signaling Regulation Laboratory have developed a new low cost reproducible system for the co-cultivation of cells. This system is based on a polymerized BSA membrane.

8 Aug 2021

New molecular and morphologic insights into chronic rejection after lung transplantation

A study of lung tissue from patients with end-stage bronchiolitis obliterans syndrome (BOS) as a complication of lung transplantation yielded molecular and morphologic insights into the development of chronic rejection.

3 Aug 2021

Hormone-resistant prostate, breast cancers added to clinical trial of experimental DNA therapy

The Republic of Belarus Ministry of Health has approved expanding the ongoing clinical trial of CureLab Oncology's Elenagen, an experimental DNA therapy, to include two new arms: 1) hormone-resistant breast cancer; and 2) hormone-resistant metastatic prostate cancer.

3 Aug 2021

Injecting mice with pulmonary endothelial cells can reverse symptoms of emphysema

Researchers at Weill Cornell Medicine and NewYork-Presbyterian in New York have discovered that injecting mice with pulmonary endothelial cells-the cells that line the walls of blood vessels in the lung-can reverse the symptoms of emphysema.

21 Jul 2021

Researchers use information theory to monitor resistance mechanisms to targeted cancer therapy

One of the major challenges in modern cancer therapy is the adaptive response of cancer cells to targeted therapies: initially, these therapies are very often effective, then adaptive resistance occurs, allowing the tumor cells to proliferate again.

21 Jul 2021

Human tissue xenografts in murine models for the study of SARS-CoV-2

Severe COVID-19 is associated with massive dysregulation of the host immune response, resulting in inflammation and the condition known as a cytokine storm. For the most part, however, the virus is barely noticeable or only mild among the young and healthy, suggesting that the route and intensity of an immune response could determine the severity of the disease.

20 Jul 2021

Research reveals clues to how a molecule improves appearance of surgery scars

Surgical scars treated with a molecule called alphaCT1 showed a long-term improvement in appearance when compared to control scars, according to multicenter, controlled Phase II clinical trials - a finding that could help surgeons improve patient outcomes.

20 Jul 2021

Students at Lewis Katz School of Medicine stand to benefit from new $1 million NIGMS grant

Rapid evolution in the field of biomedical research demands well-trained scientists. Adapting biomedical research training programs to keep up with the increasingly complex and interdisciplinary nature of the field, however, presents complex challenges for higher-education institutions.

12 Jul 2021

Study identifies specialized immune cells that sculpt inhibitory neurons to regulate brain wiring

From the bark of a puppy to the patter of rain against the window, our brains receive countless signals every second. Most of the time, we tune out inconsequential cues--the buzz of a fly, the soft rustle of leaves in the tree--and pay attention to important ones--the sound of a car horn, a bang on the door.

7 Jul 2021

Cell Signaling News and Research

Further Reading

New therapy harnesses "dancing molecules" to reverse paralysis, repair tissue after spinal cord injuries

Plant-derived compound can be beneficial in protecting the brain against Alzheimer’s disease pathology

Glycerin helps calm the red itchy patches in psoriasis model

SARS-CoV-2 viroporin activity impacts viral infectivity and pathogenicity

A family of proteins may be able to outwit emerging and re-emerging viruses

Study pinpoints an entirely new approach for treatment of biliary atresia

Research offers insights to restore blood vessel integrity during sepsis, other conditions

Researchers reveal mechanism underlying most common cause of epileptic seizures

New mathematical model can predict the optimum exercise regime for building muscle

Targeting a skin protein may reduce the severity of psoriasis, study reveals

Study identifies Foxo1 gene as a potential treatment target for hereditary lymphedema

Researchers develop new low-cost reproducible system for co-cultivation of cells

New molecular and morphologic insights into chronic rejection after lung transplantation

Hormone-resistant prostate, breast cancers added to clinical trial of experimental DNA therapy

Injecting mice with pulmonary endothelial cells can reverse symptoms of emphysema

Researchers use information theory to monitor resistance mechanisms to targeted cancer therapy

Human tissue xenografts in murine models for the study of SARS-CoV-2

Research reveals clues to how a molecule improves appearance of surgery scars

Students at Lewis Katz School of Medicine stand to benefit from new $1 million NIGMS grant

Study identifies specialized immune cells that sculpt inhibitory neurons to regulate brain wiring

Event Guide: 3rd Annual TRP Supply Chain & Manufacturing Summit eBook

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