Clinical Trial News and Research

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Oral drug avatrombopag reduces chemotherapy treatment delays, trial finds

In a phase 2 trial of patients with gastrointestinal cancers, avatrombopag helped 70% of those receiving chemotherapy to stay on treatment schedule, compared with 17% receiving placebo.

20 Jul 2026

Daily polypill significantly improves cardiac function in heart failure patients

Treatment with a "polypill" that combines multiple medications into a single daily dose significantly enhanced cardiac function and reduced hospitalizations for patients with heart failure, according to a study led by Michigan Medicine and UT Southwestern Medical Center.

20 Jul 2026

ddPCR and NGS for viral surveillance in antiviral drug development

hVIVO explains how ddPCR and NGS support viral surveillance in antiviral trials, from detection and quantification to resistance sequencing.

From hVIVO 20 Jul 2026

A breakthrough in coronary bypass surgery: AMT Medical’s SAFE-CAB results published in The Journal of Thoracic and Cardiovascular Surgery

AMT Medical B.V., a clinical-stage Dutch medical technology company, today announced that the one-year results of the SAFE-CAB II clinical trial have been published in The Journal of Thoracic and Cardiovascular Surgery.

17 Jul 2026

Diet helps people lose weight regardless of genetic obesity risk

A study reveals dietary coaching aids weight loss equally in individuals with high and low genetic obesity risk, challenging genetic determinism in weight loss.

17 Jul 2026

Blood p-tau217 levels signal cognitive impairment risk years before symptoms emerge

Higher baseline plasma p-tau217 was associated with greater 5- and 10-year risks of cognitive impairment and faster cognitive decline among 2,684 cognitively unimpaired adults. Very high levels corresponded to an estimated 38% risk at five years, but selected cohorts and limited long-term data mean routine screening and individualized prediction remain premature.

16 Jul 2026

Experimental drug shows promise against NRAS-driven melanoma

A research team from Huntsman Cancer Institute at the University of Utah (the U) reports that a groundbreaking pathway-targeted therapy could be an effective treatment for certain melanoma patients and fill an unmet clinical need for patients with advanced disease.

16 Jul 2026

Fractional COVID booster doses provide strong long-lasting immunity

Smaller doses of COVID-19 booster vaccines can provide long-lasting immunity, helping to reduce costs and improve access to vaccination, according to new research. And the findings could also inform vaccine dosing and options during future pandemics.

16 Jul 2026

Extended myeloma maintenance therapy shows no additional survival benefit

A major national cooperative group clinical trial led by Mayo Clinic researchers found that continuing maintenance therapy with lenalidomide beyond two years after initial treatment for standard-risk multiple myeloma did not improve overall survival compared with stopping treatment after two years.

15 Jul 2026

New machine learning model improves cholesterol calculation accessibility

The Martin-Hopkins equation to assess low-density lipoprotein (LDL) cholesterol levels in blood samples has been used by laboratories in the U.S. and other countries to guide efforts to lower cardiovascular disease risk.

15 Jul 2026

New photoswitchable drugs restore light perception in blind animals

Blinding diseases caused by the degeneration of photoreceptors, such as age-related macular degeneration (AMD) and retinitis pigmentosa (RP), affect 200 million people worldwide and represent the leading causes of visual impairment and blindness.

15 Jul 2026

Europe’s fragmented early access landscape intensifies need for operational strategy ahead of the 5th Operationalise: Early Access Programmes Summit Europe

Join industry leaders at the 2026 summit to discuss strategies for navigating early access programmes and improving patient access to investigational therapies.

From 5th Operationalise: Early Access Programmes Summit Europe 15 Jul 2026

Study sheds light on the prognostic value of blood test for predicting cognitive impairment risk

A blood test for the biomarker phosphorylated tau 217 (p-tau217) recently received federal clearance, but questions have emerged around the extent to which such tests can accurately predict whether a cognitively healthy individual will go on to develop cognitive impairment-a key symptom of Alzheimer's disease.

15 Jul 2026

New report highlights top ten brain health breakthroughs for clinicians

"Understanding Breakthroughs in Brain Health: Top 10 Articles of 2025" - the latest "Top 10" report in the Gerontological Society of America's Insights & Implications in Gerontology series - presents a curated collection of the year's most impactful research on cognitive decline, dementia detection, and brain health across the lifespan, with a focus on actionable insights for primary care providers.

14 Jul 2026

New project targets recurrent urinary tract infections using phages

Researchers at the HUN-REN Biological Research Centre, Szeged are participating in a €15 million Horizon Europe program that will investigate the combination of phage therapy and microbiome restoration in a European clinical trial.

14 Jul 2026

Integrating gene signatures and multi omics improves liver cancer treatment

Hepatocellular carcinoma (HCC) remains highly fatal due to late diagnosis and scarce early biomarkers.

14 Jul 2026

Medical THC and CBD formulation significantly reduces late-life dementia agitation

In a first-of-its-kind clinical trial, U.S. researchers have found that people with agitation and dementia in late life who took a special medical formulation of two active ingredients found in marijuana – THC and CBD – had significantly less agitation compared to people who received a placebo.

14 Jul 2026

Bifidobacterium-based oral vaccine enhances anti-tumor immunity in clinical study

A novel oral vaccine platform using genetically engineered Bifidobacterium could enhance anti-tumor immunity.

14 Jul 2026

Study reports a counterintuitive new approach to treating mesothelioma

Mesothelioma is a rare but aggressive cancer, usually caused by exposure to asbestos. Inhaled asbestos fibers become lodged in the lungs, causing inflammation that can lead to tumor formation decades later. Worldwide, about 30,000 people are diagnosed with mesothelioma each year.

14 Jul 2026

EpilepsyGTx partners with ClearPoint Neuro to support targeted delivery of lead gene therapy in epilepsy

EpilepsyGTx, a biotechnology company developing cutting-edge gene therapies to treat refractory epilepsy, and ClearPoint Neuro ("ClearPoint"), a global therapy-enabling company offering precise navigation and delivery to the brain, today announced a partnership to support the targeted delivery of EpilepsyGTx's lead gene therapy candidate, EPY201, for focal refractory epilepsy (FRE).

From EpilepsyGTx 14 Jul 2026

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Clinical Trial News and Research

Oral drug avatrombopag reduces chemotherapy treatment delays, trial finds

Daily polypill significantly improves cardiac function in heart failure patients

ddPCR and NGS for viral surveillance in antiviral drug development

A breakthrough in coronary bypass surgery: AMT Medical’s SAFE-CAB results published in The Journal of Thoracic and Cardiovascular Surgery

Diet helps people lose weight regardless of genetic obesity risk

Blood p-tau217 levels signal cognitive impairment risk years before symptoms emerge

Experimental drug shows promise against NRAS-driven melanoma

Fractional COVID booster doses provide strong long-lasting immunity

Extended myeloma maintenance therapy shows no additional survival benefit

New machine learning model improves cholesterol calculation accessibility

New photoswitchable drugs restore light perception in blind animals

Europe’s fragmented early access landscape intensifies need for operational strategy ahead of the 5th Operationalise: Early Access Programmes Summit Europe

Study sheds light on the prognostic value of blood test for predicting cognitive impairment risk

New report highlights top ten brain health breakthroughs for clinicians

New project targets recurrent urinary tract infections using phages

Integrating gene signatures and multi omics improves liver cancer treatment

Medical THC and CBD formulation significantly reduces late-life dementia agitation

Bifidobacterium-based oral vaccine enhances anti-tumor immunity in clinical study

Study reports a counterintuitive new approach to treating mesothelioma

EpilepsyGTx partners with ClearPoint Neuro to support targeted delivery of lead gene therapy in epilepsy

Event guide: 15th World Clinical Biomarkers & CDx Europe eBook

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