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Cerba Research expands expertise and global reach to support drug development

Cerba Research is transforming into a multi-specialist and central laboratory company, providing research organisations with even greater access to exceptional scientific and technical teams in multiple therapeutic areas for drug and vaccine development.

14 Oct 2023

EVScape: New tool to forecast which SARS-CoV-2 variants could dodge our immunity

Researchers have developed EVScape, a predictive tool that identifies which SARS-CoV-2 strains are most likely to evade host immunity. Utilizing a deep generative model and structural information, the tool offers early warning about viral variants, aiding in the timely development of effective vaccines and treatments.

12 Oct 2023

Invasive mosquito species may be spreading new form of malaria in East Africa

Turkana County in northwestern Kenya was supposed to be the land that malaria forgot. An arid, windy region abutting Uganda, South Sudan and Ethiopia, its climate was thought to be too dry for the mosquitoes that harbor malaria-causing parasites, and thus it has been excluded from national efforts to prevent the spread of the disease.

12 Oct 2023

Does your gut microbiome play a role in therapeutic outcomes?

The role of the gut microbiome and its metabolites in altering the therapeutic outcomes

12 Oct 2023

New topical drug shows promise in preventing cutaneous squamous cell carcinoma

Cutaneous squamous cell carcinoma is the second most common type of skin cancer in the United States, impacting approximately 700,000 people each year.

11 Oct 2023

Neanderthal genes make some humans more pain-sensitive

People with three Neanderthal-inherited gene variants in SCN9A are more sensitive to certain types of pain, revealing past interbreeding's genetic influence on modern humans. This study, led by UCL researchers, underscores pain sensitivity as a crucial evolutionary trait potentially shaped by Neanderthal genetics.

10 Oct 2023

Thousands got Exactech knee or hip replacements. Then, patients say, the parts began to fail.

Ron Irby expected the artificial knee implanted in his right leg in September 2018 would last two decades — perhaps longer.

10 Oct 2023

Owlstone Medical recruits first patient in phase 2 clinical trial for the early detection of lung cancer through breath biopsy

Owlstone Medical, the global leader in Breath Biopsy® for applications in early disease detection and precision medicine, today announced recruitment of the first patient into its EVOLUTION Phase 2 clinical trial following successful achievement of key safety and proof of concept milestones in Phase 1.

From Owlstone Medical Ltd 10 Oct 2023

Halting pandemics at the source: The call for a proactive 'One Health' approach

The recent PLoS Pathogens review emphasizes proactively preventing pathogen spillover from animals to humans as a strategy against future pandemics, advocating for a holistic One Health approach that considers the interconnectedness of humans, animals, and the environment. The study underscores the importance of primary prevention, differentiating it from secondary containment, and highlights the economic and societal benefits of preemptive actions over reactive responses.

10 Oct 2023

Antigenic cartography decodes the mysteries of SARS-CoV-2 variants and vaccines

Using antigenic cartography, researchers analyzed cross-reactivity patterns of SARS-CoV-2 variants and the effect of spike-protein changes on post-infection and vaccination immune responses. The study illuminated unique neutralization profiles and underscored the evolving defense mechanisms with repeated immunizations.

8 Oct 2023

Protein recombinant vaccine NVX-CoV2373 confers protection during Omicron dominant period in Italy

The NVX-CoV2373 COVID-19 vaccine offers significant protection against symptomatic infections, but its effectiveness against SARS-CoV-2 declines within four months, according to a study in JAMA Network Open using Italian data. However, its protection against symptomatic COVID-19 seems to remain stable during this period.

8 Oct 2023

Pyrvinium can be repurposed as a preventative treatment for stomach cancer

A study published Oct. 4 in Gastroenterology further validates that pyrvinium, a drug that has been used for decades for intestinal pinworms, can be repurposed as a preventative treatment for stomach cancer.

6 Oct 2023

Differences in immune responses to SARS-CoV-2 variants could inform future vaccine design

A person's immune response to variants of SARS-CoV-2, the virus that causes COVID-19, depends on their previous exposure - and differences in the focus of immune responses will help scientists understand how to optimize vaccines in the future to provide broad protection.

6 Oct 2023

Study reveals unexpected variation in genetic code of protist

Scientists testing a new method of sequencing single cells have unexpectedly changed our understanding of the rules of genetics.

6 Oct 2023

Second international consensus report outlines gaps and opportunities for clinical translation of precision diabetes medicine

Precision medicine is part of the logical evolution of contemporary evidence-based medicine that seeks to reduce errors and optimize outcomes when making medical decisions and health recommendations.

4 Oct 2023

New artemisinin-resistant malaria parasite detected in Eritrea

Diagnosis of Plasmodium falciparum malaria using rapid diagnostic tests and treatment with artemisinin derivatives, the main component of the malaria treatments recommended by the World Health Organization (WHO), are under threat in the Horn of Africa.

29 Sep 2023