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Engineered SARS-CoV-2 immunogens elicit broadly neutralizing antibodies

New research describes a novel approach whereby SARS-2 antigens were analyzed for conserved sites that may be targeted by broadly neutralizing antibodies that will confer immunity to other Sarbecoviruses.

10 Mar 2022

Study reveals differential blood glycoprotein profiles in symptomatic and asymptomatic COVID-19 patients

A new study used glycoprotein profiling technology platform that couples high-resolution LC-MS for glycoprotein analysis in regards to COVID-19.

9 Mar 2022

Study suggests recent common cold may actually lead to worse COVID-19 disease

A new study published in the Journal of Infectious Diseases shines an unexpected light on the notion that pre-existing immunity to common cold coronaviruses can protect us from coronavirus disease 2019 (COVID-19) – and reveals that this may actually put certain individuals at risk of more severe clinical presentations.

8 Mar 2022

Severity-dependent immune mechanisms in the cerebrospinal fluid and plasma of COVID-19 patients

Researchers determined the immune mechanisms associated with severe neurological manifestations of COVID-19.

7 Mar 2022

Identifying and managing drug-drug interactions key to the safe use of nirmatrelvir–ritonavir in COVID-19 treatment

Researchers compiled evidence-based recommendations in consultation with European and North American clinicians and pharmacologists for recognizing and managing drug-drug interactions with nirmatrelvir–ritonavir.

3 Mar 2022

Research uncovers a new molecular interaction mechanism for SARS-CoV2

The virus causing the current COVID-19 pandemic is the SARS-CoV-2. Soon after the pandemic outbreak in 2019, the ACE-2 protein, which is present on some of our cells´ surface, was identified as the receptor facilitating host cell viral entry.

3 Mar 2022

Cow's milk protein can trigger inflammation in multiple sclerosis sufferers

Multiple sclerosis sufferers often complain of more severe disease symptoms after consuming dairy products. Researchers at the Universities of Bonn and Erlangen-Nuremberg have now found a possible cause for this.

1 Mar 2022

A study on the evolution of avian coronavirus escape mutants in vitro

A recent study included an in vitro assessment of the effect of antibody titers and vaccine combinations on the emergence of escape mutants of AvCoV.

28 Feb 2022

Study finds lower prevalence of post-acute SARS-CoV-2 symptomology in vaccinated individuals

In a recent study, researchers evaluated the effect of COVID-19 vaccines on the symptomatic prevalence of SARS-CoV-2 infections beyond the acute phase of the disease.

28 Feb 2022

Protective immunity signatures provided by convalescent plasma for the development of COVID-19 antibody therapeutics

Researchers conducted a comprehensive and systematic analysis of functional SARS-CoV-2 antibody profiles in a controlled randomized trial of severe COVID-19 hospitalized individuals treated with COVID-19 CCP.

25 Feb 2022

Traditional Chinese medicine can be an effective radiosensitizer for patients with nasopharyngeal carcinoma

Treatment of nasopharyngeal carcinoma (NPC), a group of cancers that originate in the nose and throat, is made complicated by their unique position. Radiation therapy is often the main curative treatment for NPC. However, some patients are resistant to radiation therapy.

25 Feb 2022

Foundational characterization of a new bat-borne ebolavirus and its potential as a human pathogen

Researchers sought to evaluate the zoonotic potential of BOMV to assess the level of risk to public health.

24 Feb 2022

Immunomolecular detection method to rapidly and accurately detect complete SARS-CoV-2 virions

Researchers developed a hybrid assay incorporating immunological antibody-based viral spike protein capture with molecular nucleic acid amplification by qRT-PCR.

24 Feb 2022

Antibody levels against SARS-CoV-2 spike protein up to 12 months after COVID-19 infection in non-vaccinated individuals

A recent study assessed the persistence of SARS-CoV-2 antibody five and 12 months post-infection in non-vaccinated patients.

24 Feb 2022

Study demonstrates that TMPRSS2, which is key to SARS-CoV-2 cell entry, is a tumor suppressor

The role played by the host enzyme TMPRSS2 in infection and cancer is the focus of a new study.

23 Feb 2022

Study proposes SARS-CoV-2-encoded peptide presented by HLA-E may suppress inhibition of natural killer cells

A recent study reported the abrogation of inhibition of the NK cells by a SARS-CoV-2-encoded protein presented by HLA-E.

23 Feb 2022

Study shows BCG vaccine provides no protection against SARS-CoV-2 in mice and hamsters

Researchers investigated the effectiveness of the BCG vaccines against SARS-CoV-2 infections using three animal models.

23 Feb 2022

Omicron neutralizing titers after third BNT162b2 dose are persistent

The new study, published in the journal Cell Host and Microbe, also finds that the neutralization against Omicron remains robust at four months after the third dose of the BNT162b2 vaccine.

22 Feb 2022

Cellular automata imaging-based classification of SARS-CoV-2 variants

A new preprint classified and grouped SARS-CoV-2 variants based on their cellular automata imaging images and Hamming distances, to determine viral evolutions.

22 Feb 2022

Research explains how SARS-CoV-2 variants evade some antibodies

A recent study published in the iScience Journal assessed the influence of new variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on coronavirus disease 2019 (COVID-19) infectivity and viral neutralization.

22 Feb 2022

Glycoprotein News and Research

Engineered SARS-CoV-2 immunogens elicit broadly neutralizing antibodies

Study reveals differential blood glycoprotein profiles in symptomatic and asymptomatic COVID-19 patients

Study suggests recent common cold may actually lead to worse COVID-19 disease

Severity-dependent immune mechanisms in the cerebrospinal fluid and plasma of COVID-19 patients

Identifying and managing drug-drug interactions key to the safe use of nirmatrelvir–ritonavir in COVID-19 treatment

Research uncovers a new molecular interaction mechanism for SARS-CoV2

Cow's milk protein can trigger inflammation in multiple sclerosis sufferers

A study on the evolution of avian coronavirus escape mutants in vitro

Study finds lower prevalence of post-acute SARS-CoV-2 symptomology in vaccinated individuals

Protective immunity signatures provided by convalescent plasma for the development of COVID-19 antibody therapeutics

Traditional Chinese medicine can be an effective radiosensitizer for patients with nasopharyngeal carcinoma

Foundational characterization of a new bat-borne ebolavirus and its potential as a human pathogen

Immunomolecular detection method to rapidly and accurately detect complete SARS-CoV-2 virions

Antibody levels against SARS-CoV-2 spike protein up to 12 months after COVID-19 infection in non-vaccinated individuals

Study demonstrates that TMPRSS2, which is key to SARS-CoV-2 cell entry, is a tumor suppressor

Study proposes SARS-CoV-2-encoded peptide presented by HLA-E may suppress inhibition of natural killer cells

Study shows BCG vaccine provides no protection against SARS-CoV-2 in mice and hamsters

Omicron neutralizing titers after third BNT162b2 dose are persistent

Cellular automata imaging-based classification of SARS-CoV-2 variants

Research explains how SARS-CoV-2 variants evade some antibodies

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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