Heart Defect News and Research

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FDA approves APP Pharmaceuticals' Indomethacin for Injection

APP Pharmaceuticals, Inc., a wholly owned subsidiary of Fresenius Kabi Pharmaceuticals Holding, Inc., announced today that it has received approval from the U.S. Food and Drug Administration (FDA) to market Indomethacin for Injection. Indomethacin is therapeutically equivalent to the reference-listed drug INDOCIN® I.V., by Lundbeck, Inc.

23 Mar 2010

Researchers find retinoic acid regulates SHF tissue formation

Researchers at the Keck School of Medicine of the University of Southern California have identified a key cellular mechanism that guides embryonic heart tissue formation-a process which, if disrupted, can lead to a number of common congenital heart defects.

18 Mar 2010

Genetic basis unknown in many children with mental retardation and developmental delays

Researchers from four laboratories that perform diagnostic genetic testing of chromosome abnormalities in individuals with unexplained physical and developmental disabilities recently identified a previously unrecognized genetic disorder.

10 Mar 2010

University of Michigan's cardiac surgeon receives Nina Starr Braunwald award

The research foundation of the nation's largest group of thoracic surgeons has awarded University of Michigan's Jennifer C. Hirsch, M.D., M.S., with the Nina Starr Braunwald award, a top award for women in cardiac surgery.

4 Mar 2010

Pediatric patients face number of cardiac conditions that can impact their health

While heart disease is traditionally associated with adults, pediatric patients face a number of cardiac conditions that can impact their health.

18 Feb 2010

AGA Medical Holdings announces fourth-quarter and full-year 2009 financial results

AGA Medical Holdings, a leading developer of interventional medical devices for the minimally invasive treatment of structural heart defects and vascular abnormalities, today reported financial results for the fourth quarter and full year ended Dec. 31, 2009.

16 Feb 2010

Cardiology 2010 conference focuses on current treatments for children with heart disease

An international group of over 900 medical experts gathers today to discuss the most current treatments for children with heart disease. Affecting about 8 in every 1,000 children, congenital (present at birth) heart disease is the most common birth defect. In its severe forms, it is also the leading cause of death from birth defects in infants.

10 Feb 2010

60% of pregnant women never tested for CHD

Three out of five women who have given birth to a child with a congenital heart defect (CHD) -- the number-one birth defect and leading killer of infants and newborns -- were never tested for the defect during pregnancy. This is according to a survey just released by Little Hearts, Inc., a national organization that provides support, education, resources, networking and hope to families affected by congenital heart defects.

9 Feb 2010

Implanted ventricular assist heart pump for infants project awarded $5.6M federal contract

Researchers at the University of Pittsburgh and their collaborators have been awarded a $5.6 million federal contract to pursue the continued development of an implanted ventricular assist heart pump for infants and small children with congenital or acquired heart disease. The project aims to provide much-needed access to the sophisticated technologies that have saved the lives of older heart failure patients.

5 Feb 2010

NHLBI awarded four contracts to test new devices to help children with congenital heart defects

The National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health, has awarded four contracts totaling $23.6 million to begin preclinical testing of devices to help children born with congenital heart defects or those who develop heart failure.

5 Feb 2010

Study sheds new light on cancer metastasis

Some cells are natural rule-breakers. Neural crest cells for example, not only migrate throughout the body during development (most cells are more selective in their wandering), they are also more developmentally flexible than their predecessors (a no-no for nearly all cell types).

4 Feb 2010

Cardiac catheterization: A groundbreaking tool in the field of cardiology

Cardiac catheterizations have been a groundbreaking tool in the field of cardiology. This procedure offers a minimally invasive means for obtaining important information about the heart and its blood vessels, while also providing a less invasive treatment for certain heart conditions.

2 Feb 2010

Study shows cooling technique in heart operations does not impair neurological outcomes in children

Congenital heart defects (CHD) are the most common birth defects in humans, affecting 8 per 1000 live births with one third of affected children requiring intervention in early infancy.

28 Jan 2010

VentriPoint Diagnostics to present abstract on VMS clinical validation study

VentriPoint Diagnostics Ltd. today announced the abstract of a clinical validation study of the second application of the VentriPoint Medical System (VMS) will be presented at the American College of Cardiology's 59th Annual Scientific Session, March 14 to 16 in Atlanta, Georgia. The study demonstrates the accuracy of the method used by the VentriPoint Medical System (VMS) to generate critical heart measurements in three dimensions from two-dimensional ultrasound images with significantly greater speed and accuracy and at considerably lesser cost than is otherwise possible.

27 Jan 2010

Selective use of DHCA during surgery for CHD in infancy does not impair neurological outcomes

Congenital heart defects (CHD) are the most common birth defects in humans, affecting 8 per 1000 live births with one third of affected children requiring intervention in early infancy. Increasing numbers of survivors combined with developmental expectations for independence, behavioral self-regulation and academic achievement have led to a growing identification of neurobehavioral symptoms in some survivors. A study now suggests that a cooling technique often used in heart operations does not impair neurological outcomes.

27 Jan 2010

FDA approves first heart valve conduit that can delay need for open-heart surgery

The U.S. Food and Drug Administration today approved the Medtronic Melody Transcatheter Pulmonary Valve and Ensemble Delivery System, the first heart valve to be implanted through a catheter, or tube, in a leg vein and guided up to the heart. This new approach to the treatment of adults and children with previously implanted, poorly functioning pulmonary valve conduits can delay the need for open-heart surgery.

27 Jan 2010

First Hybrid Cath Lab in Louisiana at Tulane Hospital for Children

The Pediatric Heart Center at Tulane Hospital for Children has opened the first and only Hybrid Cath Lab in Louisiana. The cutting-edge facility -- one of only 10 in the country -- is a fully equipped pediatric catheterization lab and operating room that allows both cardiologists and surgeons to work side by side to open the chest, place delivery catheters in the heart and deploy devices. Outcomes are improved by avoiding cardiopulmonary bypass and shortened procedure times.

23 Jan 2010

Heart Defect News and Research

FDA approves APP Pharmaceuticals' Indomethacin for Injection

Researchers find retinoic acid regulates SHF tissue formation

Genetic basis unknown in many children with mental retardation and developmental delays

University of Michigan's cardiac surgeon receives Nina Starr Braunwald award

Pediatric patients face number of cardiac conditions that can impact their health

AGA Medical Holdings announces fourth-quarter and full-year 2009 financial results

Cardiology 2010 conference focuses on current treatments for children with heart disease

60% of pregnant women never tested for CHD

Implanted ventricular assist heart pump for infants project awarded $5.6M federal contract

NHLBI awarded four contracts to test new devices to help children with congenital heart defects

Study sheds new light on cancer metastasis

Cardiac catheterization: A groundbreaking tool in the field of cardiology

Study shows cooling technique in heart operations does not impair neurological outcomes in children

VentriPoint Diagnostics to present abstract on VMS clinical validation study

Selective use of DHCA during surgery for CHD in infancy does not impair neurological outcomes

FDA approves first heart valve conduit that can delay need for open-heart surgery

First Hybrid Cath Lab in Louisiana at Tulane Hospital for Children

Heart murmurs in pediatric patients is not a serious condition, says physician

Obesity in pregnant women is associated with increased risk of birth defects

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