Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

CRISPR-Cas3: A safer gene-editing tool shows promise for transthyretin amyloidosis treatment

Genetic disorders occur due to alterations in the primary genetic material, deoxyribonucleic acid (DNA), of an organism. Transthyretin amyloidosis (ATTR) is a progressive disorder involving amyloid deposits of misfolded transthyretin (TTR) proteins.

14 Jan 2026

Heart failure care gaps found among Asian American ethnic groups

Using nearly a decade of data (2015–2023) from 800+ U.S. hospitals and more than 700,000 patients overall, Northwestern researchers found that when Asian American heart failure patients are separated by ethnicity, rather than grouped together as "Asian," important differences in care emerge across groups including Filipino, Vietnamese, Chinese, Asian Indian, Korean and Japanese patients.

14 Jan 2026

Vaccines are helping older people more than we knew

Let's be clear: The primary reason to be vaccinated against shingles is that two shots provide at least 90% protection against a painful, blistering disease that a third of Americans will suffer in their lifetimes, one that can cause lingering nerve pain and other nasty long-term consequences.

14 Jan 2026

Bariatric surgery reshapes body fat and muscle more than GLP-1 drugs

Bariatric surgery and GLP-1 treatments reshape body composition differently, emphasizing the importance of sex and treatment choice in muscle preservation.

14 Jan 2026

Study identifies gene protecting the maternal heart during pregnancy

Scientists at The Lundquist Institute for Biomedical Innovation have identified a previously unknown molecular safeguard that protects the heart during pregnancy, shedding new light on the causes of peripartum cardiomyopathy (PPCM), a rare and life-threatening form of pregnancy-related heart failure.

12 Jan 2026

Weight loss drugs and surgery improve body composition in patients with obesity

Both the new weight loss drugs and bariatric (weight loss) surgery improve body composition in patients with obesity by inducing a moderate loss of fat-free mass (including lean muscle) along with a substantial reduction in fat, researchers at Vanderbilt Health have found.

9 Jan 2026

Global analysis shows widespread eligibility for GLP-1 weight management drugs

The worldwide prevalence of obesity has more than doubled in the last three decades, bringing with it an increase in weight-related diseases like diabetes, cardiovascular disease, and cancers.

8 Jan 2026

Clonal hematopoiesis linked to increased heart disease risk in cancer patients receiving treatment

About 1 in 5 patients with cancer who undergo genetic testing are incidentally found to have mutations in their blood called clonal hematopoiesis of indeterminate potential (CHIP).

8 Jan 2026

Solving the home care quandary

You're ready to leave the hospital, but you don't feel able to care for yourself at home yet.

8 Jan 2026

AI trained on sleep data predicts future disease and mortality years in advance

The SleepFM model reveals how sleep analysis can predict disease risk, offering insights into sleep's role as a vital health indicator for early intervention.

8 Jan 2026

Light daily movement linked to lower mortality risk in people with CKM syndrome

Light intensity activities, like walking or household chores, were linked to a lower risk of death for people with cardiovascular-kidney-metabolic (CKM) syndrome, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

7 Jan 2026

Nuclera eProtein Discovery System installed at leading universities in Taiwan

Nuclera, the biotechnology company accelerating drug discovery by providing rapid, easy access to functional proteins through its benchtop eProtein Discovery™ System, today announced that it has completed the first installations of eProtein Discovery in Asia, with systems now operational at the Department of Pharmacy and the Department of Chemistry at the National Taiwan University (NTU) College of Medicine and the Center for Bioscience and Biotechnology and Department of Chemical Engineering at the National Cheng Kung University (NCKU).

7 Jan 2026

A single immune protein may help explain why kidney and heart disease often develop together

This review synthesizes clinical, genetic, and mechanistic evidence showing that suPAR and related uPAR fragments are strongly associated with kidney, cardiovascular, and metabolic disease risk. It highlights suPAR as a stable biomarker of innate immune activation with potential pathogenic roles, while underscoring major gaps in assay standardization and therapeutic validation.

6 Jan 2026

Common blood signals explain why chronic diseases cluster as we age

This population-based study shows that shared and pattern-specific blood biomarkers reflect biological vulnerability underlying multimorbidity and the pace at which chronic diseases accumulate in older adults. Metabolic and systemic stress markers such as GDF15, HbA1c, cystatin C, and insulin consistently tracked higher disease burden and faster accumulation, with findings replicated across cohorts.

5 Jan 2026

Study sheds new light on the role of NSUN2 protein in cardiac hypertrophy and heart failure

A recent study published in Engineering has shed new light on the role of the protein NSUN2 in the development of cardiac hypertrophy and heart failure.

30 Dec 2025

Euphorbia neriifolia L. extract protects against cardiomyocyte injury and heart failure

Announcing a new publication for Acta Materia Medica journal. Heart failure (HF) remains a major global health challenge with limited therapeutic options, thus prompting the search for novel cardioprotective agents among traditional Chinese medicines.

30 Dec 2025