Mania News and Research

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Non-right-handedness increased in BD patients

Patients with bipolar disorder are around twice as likely to be non-right-handed as mentally healthy individuals, study results show.

30 Aug 2012

Elan commences ELND005 Phase 2 study in Bipolar I Disorder

Elan Corporation, plc today announced that it has commenced a Phase 2, placebo-controlled, safety and efficacy study of oral ELND005 as an adjunctive maintenance treatment in patients with Bipolar I Disorder (BPD 1) to delay the time to occurrence of mood episodes.

30 Aug 2012

DUP may differentiate schizoaffective disorder from BD

Among individuals with a first episode of psychotic mania (FEPM), a longer duration of untreated psychosis may differentiate patients with schizoaffective disorder from those with bipolar I disorder, study results suggest.

29 Aug 2012

Study provides new direction for research in bipolar disorder during pregnancy

The impact of bipolar disorder during pregnancy has been hotly contended among the research community. Now, a new study from Lawson Health Research Institute and Western University is sorting out the debate and calling for more targeted, prospective research.

23 Aug 2012

Non-righthandedness increased in BD patients

Patients with bipolar disorder are around twice as likely to be non-righthanded as mentally healthy individuals, study results show.

22 Aug 2012

Adolescent hypomania does not predict bipolar disorder

Results from a Swedish study show that only a small proportion of depressed adolescents with hypomania spectrum episodes will develop bipolar disorder in adulthood.

17 Aug 2012

Specific episode triggers in young adults with BD identified

Falling in love has the highest specificity for triggering manic/hypomanic episodes in young adults with bipolar disorder, while stressful life events has the highest specificity for triggering depressive episodes, researchers report.

16 Aug 2012

Sleep impairment linked to bipolar disorder course in teens

Sleep impairment plays a significant role in the course of bipolar disorder among adolescents, US study results suggest.

14 Aug 2012

Early maladaptive schemas play role in bipolar disorder functionality

Results from a Danish study suggest that seven early maladaptive schemas play a significant role in functional impairment among patients with bipolar disorder.

7 Aug 2012

Elation and irritability increase BD risk

Symptoms of elation and irritability are significantly associated with an increased likelihood for developing bipolar disorder, researchers report.

31 Jul 2012

BD II patients show altered brain activity during emotion processing

Depressed patients with bipolar II disorder show reduced activation and altered connectivity in brain regions associated with working memory and emotional learning, US researchers report.

18 Jul 2012

movin' mania, a community wide effort to address childhood obesity

Bon Secours Virginia Health System has launched movin' mania, a community wide effort to address childhood obesity, the leading health concern for children today. The health system gathered community partners and hundreds of area school children for a kickoff rally Thursday at the Science Museum of Virginia.

18 Jun 2012

Mania symptom profile changes with age

A review of published studies shows that there are significant age-group differences in the prominence of specific symptoms of mania among patients with bipolar disorder.

15 Jun 2012

NMDA antibodies increased in mania patients

Patients with bipolar disorder show increased levels of antibodies to the NR2 subunits of the N-methyl-D-aspartate receptor during periods of acute mania, researchers report.

12 Jun 2012

Mania develops in late adolescence

There is an increasing prevalence of bipolar disorder over adolescence, with late adolescence the peak period for the development of mania, research shows.

8 Jun 2012

Factors linked to relapse risk in bipolar disorder identified

A higher number of previous mood episodes and living in a mixed urban/rural area are associated with an increased risk for relapse in patients with bipolar disorder, Spanish researchers report.

1 Jun 2012

Ketamine reduces suicidal thoughts in patients with bipolar depression

Bipolar disorder is a serious and debilitating condition where individuals experience severe swings in mood between mania and depression. The episodes of low or elevated mood can last days or months, and the risk of suicide is high. Antidepressants are commonly prescribed to treat or prevent the depressive episodes, but they are not universally effective. Many patients still continue to experience periods of depression even while being treated, and many patients must try several different types of antidepressants before finding one that works for them.

31 May 2012

Anxiety increases symptom severity in acute mania patients

Anxiety is common in patients experiencing an episode of acute mania and is associated with more severe mood symptoms, researchers report.

30 May 2012

Study shows effects of psychotropic drug treatment on brain morphology

It is increasingly recognized that chronic psychotropic drug treatment may lead to structural remodeling of the brain. Indeed, clinical studies in humans present an intriguing picture: antipsychotics, used for the treatment of schizophrenia and psychosis, may contribute to cortical gray matter loss in patients, whereas lithium, used for the treatment of bipolar disorder and mania, may preserve gray matter in patients.

9 May 2012

Johnson & Johnson fined $1.2B for hiding anti-psychotic drug dangers, deceptive marketing

An Arkansas judge fined the drug maker and a subsidiary for misleading doctors and the public on the risks involved with taking an anti-psychotic drug, Risperdal, and for marketing the drug for an off-label use to the state's Medicaid system.

12 Apr 2012