UK Biobank News and Research

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Researchers assess UK biobank genome sequences

In a new study, researchers analyzed 150,119 genome sequences from the United Kingdom Biobank (UKB).

26 Jul 2022

Scientists provide first report from the largest whole genome sequencing effort to date

Scientists at deCODE genetics a subsidiary of Amgen together with collaborators from Denmark report on the whole genome sequences of 150 thousand participants in the UK biobank in a paper published in the journal Nature today.

20 Jul 2022

Study links low vitamin D level with risk of dementia

The American Journal of Clinical Nutrition has recently published a study that describes the impact of vitamin D status on brain health. The study findings reveal that vitamin D deficiency increases the risk of dementia.

18 Jul 2022

Coffee consumption during pregnancy may not be harmful

How many cups of coffee you drink when you are pregnant does not seem to negatively affect the weight of the baby, whether it is born prematurely, or your risk of miscarriage or stillbirth.

18 Jul 2022

Men with hematopoietic mosaic loss of Y chromosome have worse prognosis for heart failure

research group led by Dr. Soichi Sano, a specially appointed lecturer in the Department of Cardiovascular Medicine, Graduate School of Medicine, Osaka Metropolitan University, revealed that men with hematopoietic mosaic loss of Y chromosome (mLOY) — meaning men with an increase, in the blood, of cells that have lost the male sex chromosome — have a worse prognosis for heart failure due to fibrosis progression in the heart.

15 Jul 2022

Mosaic loss of Y chromosome increases risk for heart failure and cardiac fibrosis in men

Why a condition that frequently occurs in aging men, in which an increasing number of hematopoietic cells display a loss of the Y chromosome, is associated with increased risk of mortality and age-related diseases is now a little clearer, thanks to work in mice.

15 Jul 2022

Y chromosome loss in men can lead to deadly heart failure, research shows

The loss of the male sex chromosome as many men age causes the heart muscle to scar and can lead to deadly heart failure, new research from the University of Virginia School of Medicine shows.

14 Jul 2022

What is the association between long-term salt usage behavior and risk of premature mortality?

Researchers assessed the impact of increased salt consumption on life expectancy.

14 Jul 2022

Adding salt to foods at the table increases risk of premature death

People who add extra salt to their food at the table are at higher risk of dying prematurely from any cause, according to a study of more than 500,000 people, published in the European Heart Journal today (Monday).

9 Jul 2022

The association between handgrip strength and dementia risk in a UK population of middle-aged adults

Researchers analyzed the correlations between HGS, dementia, and neurocognitive outcomes among males and females from the United Kingdom.

27 Jun 2022

New study provides 'big picture' of the genetic landscape of Europe

A new study by RCSI University of Medicine and Health Sciences examining population genetics across Europe has analyzed the diverse ancestries of people living in the UK. This knowledge has the potential to inform future health research on genetic factors leading to disease.

13 Jun 2022

Coffee drinking causes no increased risk to pregnancy, genetic study reveals

University of Queensland researchers have found enjoying a daily latte or long black causes no increased risk to pregnancy.

13 Jun 2022

Discovery could lead to a simple screening process for predicting heart attack risk

Combining information about the pattern of blood vessels in the retina with genetic data can enable accurate prediction of an individual's risk of coronary artery disease (CAD) and its potentially fatal outcome, myocardial infarction (MI), commonly known as a heart attack.

13 Jun 2022

One in 500 men may carry an extra X or Y chromosome which could increase risk of several diseases

Around one in 500 men could be carrying an extra X or Y chromosome – most of them unaware – putting them at increased risk of diseases such as type 2 diabetes, atherosclerosis and thrombosis, say researchers at the universities of Cambridge and Exeter.

10 Jun 2022

Multiple heart-related conditions may increase dementia risk to a greater extent than genetics

Having multiple conditions that affect the heart are linked to a greater risk of dementia than having high genetic risk, according to a largescale new study.

9 Jun 2022

The association between vitamin D status and infections, hospitalization, and mortality due to COVID-19

Researchers explored the associations between vitamin D levels and SARS-CoV-2 infections, hospitalizations, and deaths in England.

8 Jun 2022

Diabetes drug's target protein can be a candidate for the treatment of Alzheimer's disease

Mechanisms associated with a particular diabetes drug can also help to protect against Alzheimer's disease, a study by researchers at Karolinska Institutet in Sweden and published in Neurology reports.

3 Jun 2022

Normal brain aging accelerated by 26% in people with progressive type 2 diabetes, study shows

Scientists have demonstrated that normal brain aging is accelerated by approximately 26% in people with progressive type 2 diabetes compared with individuals without the disease, reports a study published today in eLife.

24 May 2022

Genetics and environmental factors contribute to how socioeconomic status shapes the brain architecture

Your education, your job, your income, the neighborhood you live in: Together these factors are considered to represent socioeconomic status (SES) and contribute to a variety of health and social outcomes, from physical and mental health to educational achievement and cognitive capacities.

18 May 2022

Health screening and genetic tests may help detect people who carry a gene for familial hypercholesterolemia

Health screening and genetic tests might identify more than 1 million U.S. adults who carry a gene for familial hypercholesterolemia, a common genetic disorder that causes elevated low-density lipoprotein (LDL) cholesterol, known as "bad cholesterol," which may lead to premature heart attack or death, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

18 May 2022

UK Biobank News and Research

Researchers assess UK biobank genome sequences

Scientists provide first report from the largest whole genome sequencing effort to date

Study links low vitamin D level with risk of dementia

Coffee consumption during pregnancy may not be harmful

Men with hematopoietic mosaic loss of Y chromosome have worse prognosis for heart failure

Mosaic loss of Y chromosome increases risk for heart failure and cardiac fibrosis in men

Y chromosome loss in men can lead to deadly heart failure, research shows

What is the association between long-term salt usage behavior and risk of premature mortality?

Adding salt to foods at the table increases risk of premature death

The association between handgrip strength and dementia risk in a UK population of middle-aged adults

New study provides 'big picture' of the genetic landscape of Europe

Coffee drinking causes no increased risk to pregnancy, genetic study reveals

Discovery could lead to a simple screening process for predicting heart attack risk

One in 500 men may carry an extra X or Y chromosome which could increase risk of several diseases

Multiple heart-related conditions may increase dementia risk to a greater extent than genetics

The association between vitamin D status and infections, hospitalization, and mortality due to COVID-19

Diabetes drug's target protein can be a candidate for the treatment of Alzheimer's disease

Normal brain aging accelerated by 26% in people with progressive type 2 diabetes, study shows

Genetics and environmental factors contribute to how socioeconomic status shapes the brain architecture

Health screening and genetic tests may help detect people who carry a gene for familial hypercholesterolemia

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