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How loneliness and social isolation impact your health at the molecular level

This research identifies proteins linking social relationships to cardiovascular disease and mortality, offering insights for disease prediction and prevention.

7 Jan 2025

Social connections may boost immunity and reduce disease risk

Interactions with friends and family may keep us healthy because they boost our immune system and reduce our risk of diseases such as heart disease, stroke and type 2 diabetes, new research suggests.

3 Jan 2025

Observational studies overestimate smoking's impact on CKD risk

A recent study published in Health Data Science led by Zhilong Zhang from the Institute of Medical Technology at Peking University Health Science Center and Professor Luxia Zhang from the National Institute of Health Data Science at Peking University has shed light on the complex relationship between smoking behavior and chronic kidney disease (CKD).

2 Jan 2025

Machine learning reveals how metabolite profiles predict aging and health

Researchers developed metabolomic aging clocks using machine learning, uncovering links between metabolite profiles, health outcomes, and lifespan.

1 Jan 2025

AI-based aging clocks offer insights into health and lifespan

Researchers at the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London have conducted a comprehensive study to evaluate artificial intelligence based aging clocks, which predict health and lifespan using data from blood.

18 Dec 2024

Study reveals link between dyslexia genes and brain structure

Dyslexia is a common learning difficulty in which genes often play a role. How do genes associated with dyslexia relate to brain structure in the general population? In a large-scale study published in Science Advances, a team of scientists led by the Max Planck Institute for Psycholinguistics in Nijmegen found that genetic variants that increase the chance of dyslexia were associated with differences in brain areas involved in motor coordination, vision, and language.

18 Dec 2024

Metabolomic biomarkers improve diabetes risk prediction accuracy

Researchers developed a novel diabetes risk score integrating traditional factors with metabolomic biomarkers, achieving improved prediction accuracy for 10-year type 2 diabetes risk.

12 Dec 2024

Key plasma proteins signal critical periods in brain aging

Researchers identified 13 plasma proteins linked to brain aging, uncovering dynamic patterns and biomarkers for early intervention in aging-related brain health.

10 Dec 2024

Two distinct types of fatty liver disease identified

Researchers at Karolinska Institutet and the University of Gothenburg have identified two types of metabolic-associated fatty liver disease - a liver-specific type and a systemic type that affects other organs and tissues.

10 Dec 2024

Tea, apples, and chocolate proven to support liver health

A flavonoid-rich diet, including apples, tea, and dark chocolate, significantly lowers the risk of non-alcoholic fatty liver disease (NAFLD) and improves liver health biomarkers. These findings highlight the potential of dietary flavonoids in combating liver fat accumulation and inflammation.

9 Dec 2024

Two new subtypes of MASH revealed with different risks and outcomes

Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly referred to as nonalcoholic fatty liver disease (NAFLD), impacts roughly 30% of the global adult population.

9 Dec 2024

X-chromosome study reveals hidden genetic links to Alzheimer’s disease

A groundbreaking study explores the overlooked X-chromosome’s role in Alzheimer’s disease, revealing seven genetic loci linked to neurodegenerative decline and cognitive reserve.

9 Dec 2024

Two studies show potential for newborn genetic screening

Two studies published today in the American Journal of Human Genetics show the potential for genomic screening in newborns to address high rates of infant hospitalization and mortality in the United States.

9 Dec 2024

Early bilateral oophorectomy linked to increased Alzheimer's disease risk

Women with early bilateral oophorectomy face higher Alzheimer's risk, especially with APOE4 allele; education and hormone therapy may offer resilience.

9 Dec 2024

Depression genes amplify women's heart disease risk

Study reveals a sex-specific link between genetic risks for psychiatric disorders and cardiovascular diseases (CVDs), with women showing a higher risk of atrial fibrillation, coronary artery disease, and heart failure linked to genetic predisposition to major depression. Menopause and modifiable factors like BMI and smoking amplify these risks.

8 Dec 2024

New computational pipeline identifies key biomarkers for Alzheimer's disease

Researchers at Columbia University Mailman School of Public Health have developed a novel computational pipeline designed to identify protein biomarkers associated with complex diseases, including Alzheimer's disease (AD).

6 Dec 2024

AI predicts mortality with whole-body MRI for personalized health insights

Researchers developed a deep learning framework for whole-body MRI-based body composition analysis, predicting mortality more accurately than traditional methods. This innovative approach could revolutionize personalized risk assessments and clinical workflows.

5 Dec 2024

Early ovarian removal and APOE4 increase Alzheimer's risk in women

New research published by a team of researchers from the University of Toronto in collaboration with colleagues from the University of Alberta has found that women who have had both ovaries surgically removed before the age of 50 and carry a variant of the apolipoprotein gene, the APOE4 allele, are at high risk of late-life Alzheimer disease (AD). Use of hormone therapy mitigates this risk.

5 Dec 2024

Scientists link proteins to Alzheimer’s through cutting-edge genetic method

Researchers have developed MR-SPI, a novel method integrated with AlphaFold3, to identify causal protein biomarkers and predict their 3D structural changes in Alzheimer’s disease. This breakthrough offers insights into disease mechanisms and potential therapeutic targets.

5 Dec 2024

New framework enhances genetic prediction of drug response and side effects

A UCLA study has outlined a new framework that researchers say would improve predictive power of genetics to determine how well a patient would respond to commonly prescribed medications as well as the severity of any side effects.

5 Dec 2024