Apoptosis News and Research

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Apoptosis is programmed cell death, the body's normal method of disposing of damaged, unwanted, or unneeded cells.

A run to the coffee shop may prevent skin cancer

Researchers in the United States have discovered that the combination of daily exercise and a cup of coffee may help prevent skin cancer.

30 Jul 2007

Women more prone to brain damage from alcohol abuse than men

Alcoholism has traditionally been considered a male disease because there are many more alcoholic males than females.

27 Jul 2007

Scientits devise dimmer swith to regulate gene expression in mammal cells

Three Boston University biomedical engineers have created a genetic dimmer switch that can be used to turn on, shut off, or partially activate a gene's function. Professor James Collins, Professor Charles Cantor and doctoral candidate Tara Deans invented the switch, which can be tuned to produce large or small quantities of protein, or none at all.

27 Jul 2007

Nanoscale dots target and track apoptosis

Apoptosis, or programmed cell death, is a hallmark effect triggered by effective anticancer drugs. Now, researchers in Korea have developed a biocompatible, fluorescent nanoparticle that could provide an early sign that apoptosis is occurring as a result of anticancer therapy.

23 Jul 2007

Scientists clarify molecular basis of interferon action

Scientists at the University of California, Santa Barbara have made a significant discovery relating to viral infections in humans.

20 Jul 2007

Suicide gene therapy for cancer

Cutting-edge research at South Dakota State University may yield a new therapy that targets only cancer cells, leaving healthy cells unharmed.

18 Jul 2007

Researchers identify new combination therapy that promotes cancer cell death

Researchers at the University of Pennsylvania School of Medicine identified a combination therapy as a way to sensitize resistant human cancer cells to a treatment currently being tested in clinical trials They propose that the therapy may help to selectively eliminate cancer cells while leaving healthy cells intact, providing a cancer treatment with fewer side effects.

17 Jul 2007

Bak protein's deadly double whammy

When a cell is seriously stressed, say by a heart attack, stroke or cancer, a protein called Bak just may set it up for suicide, researchers have found.

13 Jul 2007

New advance in search for effective treatment for human liver cancer

Researchers from the University of Pittsburgh School of Medicine report a significant new advance in the search for an effective treatment for human liver cancer in the July issue of Molecular Cancer Therapeutics.

12 Jul 2007

Scientists take exciting approach for attacking cancers

A new study identifies a combination therapy that may sensitize human cancer cells to a promising treatment currently being used in clinical trials.

10 Jul 2007

New working principle in cancer treatment

Due to defects in chromosomal distribution, a majority of tumor cells would not be able to survive were it not for a trick that cancer cells have developed to avoid this chaos in the genetic material.

5 Jul 2007

New type of drug shows promise for chronic lymphocytic leukemia

A new type of engineered drug candidate has shown promise in treating chronic lymphocytic leukemia in both test tube and early animal tests, a new study shows.

29 Jun 2007

New model for signal transduction in cells

Among the key communication systems within a cell is the Wnt signaling pathway, which regulates embryonic development and whose deregulation can also contribute to cancer development.

28 Jun 2007

Animal studies shouldn't alter anesthesiology practice in newborns

Recent studies showing that commonly used anesthetic agents can cause brain damage in animals don't prove that similar harmful effects occur in human newborns - and shouldn't affect current approaches to anesthesia in preterm and ill infants, according to a leading expert on pain management in newborns.

26 Jun 2007

New cancer drug target

Research led by scientists at Weill Cornell Medical College has uncovered two new potential points of vulnerability on a key cancer-promoting protein, called XIAP.

23 Jun 2007

DNA repair by Brca2 prevents medulloblastoma

St. Jude investigators have gained some of the first major insights into how certain genes known to prevent cancer also guide the nervous system's normal development before birth and during infancy by repairing DNA damage.

23 Jun 2007

Sensitivity to diverse range of chemotherapeutic drugs linked to common pathway

Using a functional genomic screen, scientists have defined elements that impact the responsiveness of cancer cells to drugs commonly used as anticancer therapeutics.

15 Jun 2007

Nanoparticle-enabled peptide delivery triggers tumor regression

Cells possess a variety of ways of dealing with mutations that can cause them to grow uncontrollably and eventually form a tumor. The tumor suppressor gene p53 plays a critical role in these cancer prevention processes, largely by triggering a form a cell death known as apoptosis.

14 Jun 2007

Double-duty nanoparticles overcome drug resistance in tumors

Cancer cells, like bacteria, can develop resistance to drug therapy. In fact, research suggests strongly that multidrug resistant cancer cells that remain alive after chemotherapy are responsible for the reappearance of tumors and the poor prognosis for patients whose cancer recurs.

14 Jun 2007

Cholesterol causes changes in gene expression

Experts from the University of Granada carried out research on atherosclerosis from its earliest stages to discover the origin of atheromatous plaques, fatty deposits gradually and irregularly formed in the main arteries, causing the narrowing of the blood vessel.

14 Jun 2007