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University of Notre Dame receives funding to help launch diabetic ulcer drug over 'Valley of Death'

Thousands of new chemical structures are tested in hopes of discovering a single drug meant to treat a single disease. Of the 5,000 to 10,000 that are prepared, only about 250 of those make it to the pre-clinical stage, and potentially as few as five make it to clinical trials in humans.

8 Oct 2019

New way to prevent malaria bugs from breeding

A new international collaboration reports that the compound called TCMDC-135051 is capable of preventing the synthesis of a protein that is required for growth in Plasmodium falciparum, one of the species of the Plasmodium parasite that causes malaria. The study, reported in the journal Science, could lead to the development of a new antimalarial drug.

8 Oct 2019

Researchers determine how the colon prioritizes gas detox over energy use

Onions, cabbage, garlic. While nutritious, eating these foods can lead to an embarrassing side effect: smelly flatulence. More than just smelly, hydrogen sulfide, the chemical compound responsible for the rotten-egg aroma, is deadly if inhaled at doses of more than 700 parts per million.

7 Oct 2019

New device can accelerate bone regeneration in difficult cases

Within minutes of breaking a bone, the body begins to repair itself.

7 Oct 2019

GlobalData: Alternative livestock feed to aid in the production of sustainable meat

Meat substitute sales in the UK recorded growth at a compound annual growth rate (CAGR) of 8.8% between 2013 and 2018, which was significantly higher than meat at a CAGR of 1.8% for the same timeframe.

4 Oct 2019

Experts discuss sex-specific sensitivity to key blood pressure hormone

Aldosterone is a steroid hormone important to the regulation of salt, fluid and potassium in the body.

4 Oct 2019

A new delivery system for insoluble drugs

Stable metal organic frameworks are prized for their ability to capture carbon dioxide or harvest atmospheric water, but U-M researchers have developed a use for unstable metal organic frameworks: as a system for drug delivery.

4 Oct 2019

Short-term probiotic therapy regimen may improve symptoms of gout, kidney disease

New research suggests that an individualized probiotic therapy regimen may improve symptoms of gout, gout-related kidney disease and other signs of metabolic syndrome.

4 Oct 2019

New anticancer molecule shows therapeutic activity in preclinical models of various cancer types

A novel anticancer molecule created by researchers at The Wistar Institute showed therapeutic activity in preclinical models of various cancer types.

3 Oct 2019

UCR biochemist receives grant to develop novel lead compound to treat breast cancer

A biochemist at the University of California, Riverside, has received a grant from the Congressionally Directed Medical Research Programs, or CDMRP, of the U.S. Department of Defense to develop a novel lead compound to treat breast cancer, the second most commonly diagnosed cancer among American women.

3 Oct 2019

Innovative compound kills cancer cells, minimizes damage to normal tissues

Most of the current clinical anti-tumor drugs used in chemotherapy move around in the patient's blood after intake and are unable to pinpoint the targeted tumor. As a result, while killing the tumor cells, the healthy cells may also be killed as "collateral damage", leading to undesired side effects.

3 Oct 2019

Vaping-associated lung injury most likely caused by toxicity from noxious chemical fumes

Research into the pathology of vaping-associated lung injury is in its early stages, but a Mayo Clinic study published in The New England Journal of Medicine finds that lung injuries from vaping most likely are caused by direct toxicity or tissue damage from noxious chemical fumes.

3 Oct 2019

Researchers create new material with antifungal and antitumor properties

A new material with antifungal and antitumor properties has been developed by researchers at the Center for Development of Functional Materials (CDMF), one of the Research, Innovation and Dissemination Centers (RIDCs) supported by São Paulo Research Foundation - FAPESP.

3 Oct 2019

Household bleach may be contributing to harmful indoor pollution

While the risks from ingesting chlorine bleach are clear, less obvious risks concerning airborne particles emanating from the bleach have been identified in a new study.

2 Oct 2019

Skin-lightening cream put a woman into a coma. It could happen again.

She had been buying face cream through a friend of a friend for 12 years. This time, it was Pond's "Rejuveness," a version of the company's anti-wrinkle cream that is made and sold in Mexico.

1 Oct 2019

Stem cells derived from patients could lead to new treatments for congenital muscular dystrophies

Researchers at Queen Mary University of London and University College London have shown that using stem cells derived from patients could help find new treatments for a group of congenital muscular dystrophies.

30 Sep 2019

US Government supports Kinoxis Therapeutics to end opioid addiction

Kinoxis Therapeutics has been awarded a grant for a potential of up to $US4.6 million ($6.8 million) under the USA National Institutes of Health Helping to End Addiction Long-Term, or the NIH HEAL Initiative.

30 Sep 2019

New technique can rapidly image synaptic proteins at high resolution

Our brains contain millions of synapses -- the connections that transmit messages from neuron to neuron. Within these synapses are hundreds of different proteins, and dysfunction of these proteins can lead to conditions such as schizophrenia and autism.

26 Sep 2019

New compound could take on lethal fungal, bacterial infections in immunocompromised people

Immunodeficiency is the condition where the capability of the immune system to fight against diseases has been compromised.

25 Sep 2019

Streamlining the compound ordering process for life scientists in the US

Molport has announced its expansion into the US with the opening of MolPort Inc., which will streamline the compound ordering process for US customers.

25 Sep 2019

Compound News and Research

University of Notre Dame receives funding to help launch diabetic ulcer drug over 'Valley of Death'

New way to prevent malaria bugs from breeding

Researchers determine how the colon prioritizes gas detox over energy use

New device can accelerate bone regeneration in difficult cases

GlobalData: Alternative livestock feed to aid in the production of sustainable meat

Experts discuss sex-specific sensitivity to key blood pressure hormone

A new delivery system for insoluble drugs

Short-term probiotic therapy regimen may improve symptoms of gout, kidney disease

New anticancer molecule shows therapeutic activity in preclinical models of various cancer types

UCR biochemist receives grant to develop novel lead compound to treat breast cancer

Innovative compound kills cancer cells, minimizes damage to normal tissues

Vaping-associated lung injury most likely caused by toxicity from noxious chemical fumes

Researchers create new material with antifungal and antitumor properties

Household bleach may be contributing to harmful indoor pollution

Skin-lightening cream put a woman into a coma. It could happen again.

Stem cells derived from patients could lead to new treatments for congenital muscular dystrophies

US Government supports Kinoxis Therapeutics to end opioid addiction

New technique can rapidly image synaptic proteins at high resolution

New compound could take on lethal fungal, bacterial infections in immunocompromised people

Streamlining the compound ordering process for life scientists in the US

Enhancing confidence in chemical ionization spectrometry data eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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