Gastroenterology News and Research

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Gastroenterology is the branch of medicine where the digestive system and its disorders are studied.

Majority of cancers are due to epigenetic influences

Dr. Ajay Goel, Ph.D., Director of Epigenetics and Cancer Prevention at the Gastrointestinal Research Center at Baylor University Medical Center in Dallas, TX, has announced plans for a series of upcoming studies to continue to unlock the mechanisms by which curcumin prevents cancer via its influence on epigenetic activity.

23 Jun 2011

FDA grants Fast Track designation for Repligen's RG3039 to treat Spinal Muscular Atrophy

Repligen Corporation announced today that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation for RG3039, a potential treatment for Spinal Muscular Atrophy.

23 Jun 2011

Telaprevir drug shows promise in curing hepatitis C infection

The drug telaprevir (Incivek) provides a dramatic improvement in the treatment of the most common form of hepatitis C infection, says an international team of investigators led by Dr. Ira M. Jacobson of NewYork-Presbyterian Hospital/Weill Cornell Medical Center.

23 Jun 2011

FDA approves ProStrakan's Rectiv for pain associated with anal fissures

ProStrakan Group plc, a subsidiary of Kyowa Hakko Kirin Co. Ltd., and an international specialty pharmaceutical company, today announces that it has received approval from the U.S. Food and Drug Administration (FDA) for Rectiv™ (nitroglycerin) Ointment 0.4 % for the treatment of moderate to severe pain associated with chronic anal fissures.

22 Jun 2011

Veritract to develop 'Smart Feeding Tube' with live camera and steering mechanism

Feeding tubes are not as harmless as they seem. Every year in the U.S. over 40,000 feeding tubes are mistakenly placed into a patient's lungs, which results in an estimated 6,000 deaths. But a University of Utah startup company, Veritract Inc., hopes to end these risks by making the placement of feeding tubes much safer and faster.

20 Jun 2011

ClinTec opens fully registered offices in China, Singapore and Thailand for clinical research

UK based Global Clinical Research Organisation (CRO), ClinTec International has continued its international expansion by opening fully registered offices in China, Singapore and Thailand - consolidating its presence in the Asia Pacific region.

16 Jun 2011

Children's Medical Center to open new $21M Specialty Care Center in Southlake

Children's Medical Center will debut its new Specialty Care Center in Southlake on June 18, a $21 million expansion which will serve children in one of the state's fastest-growing cities and the surrounding communities.

16 Jun 2011

USPTO issues patent to EndoSphere's noninvasive device for treatment of obesity

EndoSphere Inc., a medical technology company that holds 23 U.S. and international issued and pending patents, announced today that the U.S. Patent and Trademark Office has issued the company a patent covering the use of its endoscopically implantable devices for the treatment of metabolic diseases, including obesity and type 2 diabetes.

16 Jun 2011

Liver stiffness measurement could replace liver biopsy for evaluation of hepatitis C

Non-invasive tests for liver fibrosis, such as liver stiffness measurement or the FibroTest, can predict survival of patients with chronic hepatitis C, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute.

15 Jun 2011

Alios, Vertex sign worldwide license agreement to develop new hepatitis C combination medicines

Vertex Pharmaceuticals Incorporated and Alios BioPharma, Inc. today announced an exclusive worldwide licensing agreement that will add two distinct nucleotide analogues to Vertex's hepatitis C portfolio.

13 Jun 2011

AGA honors outstanding high school students with 2011 research fellowship awards

The American Gastroenterological Association (AGA) Research Foundation has announced the 2011 Student Research Fellowship Award recipients. Funded by The Eli and Edythe Broad Foundation, the awards are intended to stimulate interest in research careers in digestive diseases.

10 Jun 2011

Repligen total revenue increases 30% to $27,291,000 for fiscal year 2011

Repligen Corporation today reported results for the fourth quarter and fiscal year 2011, ended March 31, 2011.

9 Jun 2011

Hepatitis C virus (HCV)-associated liver disease after liver transplantation

Hepatitis C virus (HCV)-associated liver disease continues to be the most common indication for liver transplantation (LT) in the United States accounting for nearly 50% of all liver transplants. Recurrence is universal in patients viremic at the time of transplantation with histological hepatitis developing in the majority of patients. Although the natural history of recurrent HCV is difficult to predict, it is widely accepted that cirrhosis from recurrent HCV occurs in up to 30% of patients within five years of transplantation.

8 Jun 2011

Overweight increases risk of liver cirrhosis in men

Overweight carries a greatly increased risk of cirrhosis of the liver in men, reveals a new study from the Sahlgrenska Academy. "Given the increasing problem of overweight in Sweden, there is reason to fear that more people will develop cirrhosis of the liver," says Jerzy Kaczynski, docent at the University of Gothenburg and doctor at Sahlgrenska University Hospital.

8 Jun 2011

Hepatitis C patients with chronic liver disease may benefit from drinking coffee during treatment

Advanced hepatitis C patients with chronic liver disease may benefit from drinking coffee during treatment, according to a new study in Gastroenterology, the official journal of the American Gastroenterological Association (AGA) Institute.

8 Jun 2011

Shire Canada receives expanded indication for MEZAVANT for treatment of ulcerative colitis

Shire Canada Inc., a division of Shire plc, the global specialty biopharmaceutical company, is proud to announce that MEZAVANT® (mesalamine delayed and extended release tablets), the first and only once-daily mesalamine indicated for the induction of clinical and endoscopic remission in patients with mild-to-moderate, active ulcerative colitis (UC), has received an expanded indication to include maintenance of clinical and endoscopic remission (mucosal healing) in patients with ulcerative colitis.

7 Jun 2011

Trifunctional antibody Catumaxomab triggers vaccination effect against cancer

TRION Pharma GmbH has announced that the results from two different studies demonstrate catumaxomab’s capacity to activate the immune system in a way that can otherwise only be achieved through vaccination. The data were obtained by two independent research teams using catumaxomab in malignant ascites and gastric cancer, respectively. The results were recently presented at the annual meeting of the American Society of Clinical Oncology (ASCO).

6 Jun 2011

Gleevec shows significant overall survival benefit for patients w/ GIST after 3 years of adjuvant treatment vs. 1 year

Novartis announced new data today showing a significant improvement in both recurrence-free survival and overall survival for patients taking Gleevec® (imatinib mesylate)* tablets for three years after surgery to remove KIT (CD117)-positive gastrointestinal stromal tumors (KIT+ GIST) compared to one year of treatment. These data will be presented at the 47th American Society of Clinical Oncology (ASCO) plenary session on Sunday, June 5.

6 Jun 2011

EUS-guided GI biopsies with Cook Medical's new, large-core biopsy needle overcomes limitations

Results from a multicenter European study suggest that a new, large-core biopsy needle designed for use with an endoscopic ultrasound (EUS) scope may help to overcome limitations of current EUS methods for biopsies of lesions in the gastrointestinal (GI) tract and surrounding tissue.

6 Jun 2011

American College of Gastroenterology offers resources on foodborne illness, tips for food safety

For consumers in the United States concerned by the outbreak of E. coli in Europe, the American College of Gastroenterology offers background on foodborne illness, tips for food safety, and expert insight from its resources on digestive health on what to do in the case of foodborne illness.

4 Jun 2011

Gastroenterology News and Research

Further Reading

Majority of cancers are due to epigenetic influences

FDA grants Fast Track designation for Repligen's RG3039 to treat Spinal Muscular Atrophy

Telaprevir drug shows promise in curing hepatitis C infection

FDA approves ProStrakan's Rectiv for pain associated with anal fissures

Veritract to develop 'Smart Feeding Tube' with live camera and steering mechanism

ClinTec opens fully registered offices in China, Singapore and Thailand for clinical research

Children's Medical Center to open new $21M Specialty Care Center in Southlake

USPTO issues patent to EndoSphere's noninvasive device for treatment of obesity

Liver stiffness measurement could replace liver biopsy for evaluation of hepatitis C

Alios, Vertex sign worldwide license agreement to develop new hepatitis C combination medicines

AGA honors outstanding high school students with 2011 research fellowship awards

Repligen total revenue increases 30% to $27,291,000 for fiscal year 2011

Hepatitis C virus (HCV)-associated liver disease after liver transplantation

Overweight increases risk of liver cirrhosis in men

Hepatitis C patients with chronic liver disease may benefit from drinking coffee during treatment

Shire Canada receives expanded indication for MEZAVANT for treatment of ulcerative colitis

Trifunctional antibody Catumaxomab triggers vaccination effect against cancer

Gleevec shows significant overall survival benefit for patients w/ GIST after 3 years of adjuvant treatment vs. 1 year

EUS-guided GI biopsies with Cook Medical's new, large-core biopsy needle overcomes limitations

American College of Gastroenterology offers resources on foodborne illness, tips for food safety

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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