Immune Response News and Research

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New data-driven mechanistic approach can help reduce drug costs and treat diseases

A new data-driven mechanistic approach that predicts cell types within tissue will help to reduce drug costs and treat diseases that were difficult to develop drugs for, according to a West Virginia University scientist.

14 Apr 2022

Exploring strategies for successful delivery of messenger RNA therapeutics

Researchers reviewed the material properties and administration routes that could successfully deliver a messenger ribonucleic acid therapeutic agent to its targeted site.

14 Apr 2022

Dietary influences on long COVID in children

A new study discusses possible mechanisms of long COVID in children and how they might relate to their dietary intake of important vitamins and elements.

13 Apr 2022

Structural differences between SARS-CoV-1 and SARS-CoV-2 RBDs

A new study compares the SARS-CoV-2 RBD to the SARS-CoV RBD using computational methods to understand their binding affinities to ACE2.

13 Apr 2022

Novel transdermal vaccine delivery for COVID-19 and cancer

Researchers assess the efficacy of a fluorocarbon modified chitosan system for the development of SARS-CoV-2 vaccines and tumor immunotherapy.

13 Apr 2022

Additional booster doses of COVID-19 vaccine help protect solid organ transplant recipients

Additional booster doses of vaccine against COVID-19 are particularly important for those who are immunosuppressed, namely those who have had solid organ transplants, a new study shows.

13 Apr 2022

Mayo Clinic researchers devise a combination approach to more effectively target solid tumors

Researchers at Mayo Clinic's Center for Individualized Medicine have devised an immunotherapy technique that combines chimeric antigen receptor-T cell therapy, or CAR-T cell therapy, with a cancer-killing virus to more effectively target and treat solid cancer tumors.

13 Apr 2022

Impact of COVID-19 infection and vaccination on antibody response

A new study assessed the impact of COVID-19 and vaccination on antibody responses.

13 Apr 2022

Researchers identify certain gene regulation signatures in CAR T-resistant leukemia patients

Acute lymphoblastic leukemia (ALL) cells from patients whose cancers did not respond to CD19-targeted CAR T therapy had gene regulation signatures that could potentially facilitate treatment resistance, according to results presented at the AACR Annual Meeting 2022, held April 8-13.

13 Apr 2022

Zika virus can mutate to become more infective and dangerous, finds study

LA JOLLA, CA - Researchers at La Jolla Institute for Immunology (LJI) have found that Zika virus can mutate to become more infective - and potentially break through pre-existing immunity.

13 Apr 2022

Treg cell Notch receptors drive SARS-CoV-2-induced MIS-C

In a recent study under consideration at Nature Portfolio Journal and posted to the Research Square* preprint server, researchers demonstrated the evolution of multi-system inflammatory syndrome in children (MIS-C) following acute severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

12 Apr 2022

Antibody response following Omicron BA.2 infection is lower than BA.1

In a recent report posted to the medRxiv* preprint server, researchers determined immune responses generated by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.2 and BA.1 sublineage infections in prior virus-infected and naïve subjects.

12 Apr 2022

Innovative imaging technique may pave the way for better understanding and treatment of spinal cord injury

A research team led by scientists from the Hong Kong University of Science and Technology has developed an innovative technology for in vivo imaging of the important biological processes involved in the injury and repair of spinal cords, paving the way for a better understanding of the pathology and potential treatment of spinal cord injury (SCI).

12 Apr 2022

New COVID-19 vaccine induces T-cell immune responses in most patients with B-cell deficiencies

CoVac-1, a new vaccine against SARS-CoV-2, induced T-cell immune responses in 93 percent of patients with B-cell deficiencies, including many patients with leukemia and lymphoma, according to results presented at the AACR Annual Meeting 2022, held April 8-13.

12 Apr 2022

Injection-free dermally delivered subunit vaccine strongly neutralizes SARS-CoV-2 variants

Researchers in Australia have evaluated the vaccine candidature of HexaPro S protein subunit vaccine against SARS-CoV-2.

12 Apr 2022

Decoy nanoparticles could provide a quick, effective treatment for COVID-19

They might look like cells and act like cells. But a new potential COVID-19 treatment is actually a cleverly disguised trickster, which attracts viruses and binds them, rendering them inactive.

12 Apr 2022

Heart complications uncommon for children and young adults after SARS-CoV-2 infection

Heart complications are uncommon, yet treatable for children and young adults after COVID-19 disease or SARS-CoV-2 infection, according to a new scientific statement from the American Heart Association that details what has been learned about how to treat, manage and even prevent cardiovascular complications from the SARS-CoV-2 virus in youth.

12 Apr 2022

Researchers elucidate how ovarian tumors defy immunotherapy

Researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health, with collaborators at La Jolla Institute for Immunology and elsewhere, have further elucidated how ovarian cancer tumors defy immunotherapy, identifying new molecular targets that might boost immune response.

12 Apr 2022

Experimental tool can precisely pick out interactions between immune cell and target antigen

The human body has millions of unique B and T cells that roam the body, looking for microbial invaders. These immune cells' ability to recognize harmful microbes is critical to successfully fighting off infection.

12 Apr 2022

Scientists find critical role for Hippo signaling pathway in COVID-19 pathogenesis

A recent article posted to the bioRxiv* preprint server illustrated that the activation of the Hippo signaling pathway upon severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection aids the host antiviral response.

11 Apr 2022

Immune Response News and Research

New data-driven mechanistic approach can help reduce drug costs and treat diseases

Exploring strategies for successful delivery of messenger RNA therapeutics

Dietary influences on long COVID in children

Structural differences between SARS-CoV-1 and SARS-CoV-2 RBDs

Novel transdermal vaccine delivery for COVID-19 and cancer

Additional booster doses of COVID-19 vaccine help protect solid organ transplant recipients

Mayo Clinic researchers devise a combination approach to more effectively target solid tumors

Impact of COVID-19 infection and vaccination on antibody response

Researchers identify certain gene regulation signatures in CAR T-resistant leukemia patients

Zika virus can mutate to become more infective and dangerous, finds study

Treg cell Notch receptors drive SARS-CoV-2-induced MIS-C

Antibody response following Omicron BA.2 infection is lower than BA.1

Innovative imaging technique may pave the way for better understanding and treatment of spinal cord injury

New COVID-19 vaccine induces T-cell immune responses in most patients with B-cell deficiencies

Injection-free dermally delivered subunit vaccine strongly neutralizes SARS-CoV-2 variants

Decoy nanoparticles could provide a quick, effective treatment for COVID-19

Heart complications uncommon for children and young adults after SARS-CoV-2 infection

Researchers elucidate how ovarian tumors defy immunotherapy

Experimental tool can precisely pick out interactions between immune cell and target antigen

Scientists find critical role for Hippo signaling pathway in COVID-19 pathogenesis

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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