L.L. News and Research

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Genetic variations that increase PKC alpha activity may influence development of Alzheimer's disease

In Alzheimer's disease, plaques of amyloid beta protein accumulate in the brain, damaging connections between neurons.

11 May 2016

Simultaneous DNA, RNA and protein analysis to enhance cancer immunology studies: an interview with Dr Joseph Beechem

Cancer immunology is all about how your immune cells are going to fight and kill your tumor cells. If you look at the pure genetic code of a T-cell that's going to kill your tumor compared to the same cell that has been “put-to-sleep” (by the tumor), the pure genetic DNA content of those two cells are identical.

From NanoString Technologies 11 May 2016

Novel animal model helps understand mechanisms that lead to multiple myeloma

Researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have developed an animal model that allows them to better understand the mechanisms that lead to the development of multiple myeloma, a hematologic cancer of plasma cells, and the amyloidosis that sometimes accompanies it. The study was published in the journal Scientific Reports.

6 May 2016

Scientists discover how immune system molecule hijacks brain circuit to reduce appetite during illness

Loss of appetite during illness is a common and potentially debilitating phenomenon--in cancer patients, especially, it can even shorten lifespan.

5 May 2016

Enzyme previously thought beneficial could pose threat to developing embryos

A pair of Oklahoma Medical Research Foundation scientists have discovered that an enzyme previously thought only to be beneficial could, in fact, pose significant danger to developing embryos. The new research could have implications not only for prenatal development but also for treating lymphedema and liver damage resulting from acetaminophen overdose.

5 May 2016

Certain sugars in the body play key role in colitis, colon cancer development

An Oklahoma Medical Research Foundation scientist has discovered that certain sugars produced by the body play an important role in the development of colitis and, ultimately, colon cancer. The new finding could potentially lead to therapies for ulcerative colitis, Crohn's disease and colon cancer.

5 May 2016

Autistic children score almost exactly same as neurotypical kids in tests of learning new words

A new study has found that children with autism are capable of learning new words the same way any child would—by following someone's gaze as they name an object. They just take longer to pick up the skill.

4 May 2016

Advances in telemedicine: an interview with Dr Ameet Bakhai

Telemedicine is the art of improving patient care via managing data remotely, and in this spirit one of the earliest examples often not considered in this category, would be the permanent pacemaker, first implanted into a human being in 1958.

2 May 2016

New version of obesity drug could help people reduce weight without experiencing anxiety, depression

A new version of an obesity drug that caused serious psychiatric side effects could help people lose pounds without experiencing the anxiety, depression and suicidal thoughts previously associated with it. The research, published in Bioorganic and Medicinal Chemistry, shows that the new version of the drug can still work without reaching the brain in rats, avoiding the side effects.

29 Apr 2016

Quality of life assessment tools and measures not widely used in treatment of cancer patients

A new study, conducted by the not-for-profit research organisation RAND Europe, has found that measures and tools used to assess quality of life are not being used widely in the treatment and care of patients with cancer, despite being used more widely in clinical trials.

29 Apr 2016

Diagnosing heart attacks in 1 hour: an interview with Dr Richard Body

Cardiac troponin is a highly sensitive and specific biomarker for myocardial injury but concentrations in the blood rise over several hours after the onset of an acute myocardial infarction.

28 Apr 2016

New national database could help identify major influences on miscarriage

A new national database could help relieve the misery of miscarriage for thousands of women.

26 Apr 2016

Motivational interviewing can help reduce risky use of pain pills

As America battles an epidemic of deaths from misused pain pills, a new study suggests an inexpensive way to cut risky use of these drugs by people who have a high chance of overdosing.

21 Apr 2016

Using Proteomics to Understand Alzheimer’s: An Interview with Dr Renã Robinson

In our bioanalytical mass spectrometry lab we use proteomics techniques to try to understand more about Alzheimer's disease. The primary thrust of our research is that we're interested in understanding the changes that take place outside of the brain and how those correlate with what's taking place inside the brain

From Pittcon 21 Apr 2016

Daily dark chocolate consumption could help improve athletic performance

Dark chocolate has already been hailed for its positive effects on cardiovascular health - and now a study undertaken at London's Kingston University has found the tasty treat could help give sports enthusiasts an extra edge in their fitness training.

20 Apr 2016

Reducing hair loss during chemotherapy: an interview with Richard Paxman

The basic principle of chemotherapy is to damage the mitotic and metabolic processes in the cancer cells. The chemotherapy doesn't just target the cancer cells, it also targets the healthy cells, specifically ones that are rapidly dividing - our hair follicles are also rapidly dividing. We see damage to those hair cells, which then causes the hair to fall out.

From Paxman 19 Apr 2016

How will IoT impact healthcare? An interview with David Doherty

IoT is a term being used to help communicate the complex transition that's happening as Mobile transforms the Internet into a network of devices. The idea of the internet being something we go to and use a mouse to navigate is dead as we now can talk to SIRI on our mobiles to immediately summon Uber cars and buy things from Amazon that will arrive in just a few hours. Welcome to a new world!

18 Apr 2016

Combination of sugar and polyphenols may prevent occurrence of neurodegenerative disease

Catherine Aaron and Gabrielle Beaudry were 17 when they knocked on the door of the laboratory of Alex Parker, a neuroscience researcher at the University of Montreal Hospital Research Centre. While students at Collège Jean-de-Brébeuf in Montreal, they were looking for a mentor for an after-school research project. Two and half years later, the results of this scientific adventure were published today in the Journal of Agricultural and Food Chemistry.

13 Apr 2016

Tips to help treat corns and calluses

Ever wonder what causes corns and calluses? According to dermatologists from the American Academy of Dermatology, these hard, thickened areas of skin form as a result of friction or pressure on the skin. In fact, they say, corns and calluses develop naturally to help protect the skin underneath them.

13 Apr 2016

New U of T study shows that acetaminophen could impede error-detection in the brain

It's been known for more than a century that acetaminophen is an effective painkiller, but according to a new U of T study it could also be impeding error-detection in the brain.

11 Apr 2016

L.L. News and Research

Genetic variations that increase PKC alpha activity may influence development of Alzheimer's disease

Simultaneous DNA, RNA and protein analysis to enhance cancer immunology studies: an interview with Dr Joseph Beechem

Novel animal model helps understand mechanisms that lead to multiple myeloma

Scientists discover how immune system molecule hijacks brain circuit to reduce appetite during illness

Enzyme previously thought beneficial could pose threat to developing embryos

Certain sugars in the body play key role in colitis, colon cancer development

Autistic children score almost exactly same as neurotypical kids in tests of learning new words

Advances in telemedicine: an interview with Dr Ameet Bakhai

New version of obesity drug could help people reduce weight without experiencing anxiety, depression

Quality of life assessment tools and measures not widely used in treatment of cancer patients

Diagnosing heart attacks in 1 hour: an interview with Dr Richard Body

New national database could help identify major influences on miscarriage

Motivational interviewing can help reduce risky use of pain pills

Using Proteomics to Understand Alzheimer’s: An Interview with Dr Renã Robinson

Daily dark chocolate consumption could help improve athletic performance

Reducing hair loss during chemotherapy: an interview with Richard Paxman

How will IoT impact healthcare? An interview with David Doherty

Combination of sugar and polyphenols may prevent occurrence of neurodegenerative disease

Tips to help treat corns and calluses

New U of T study shows that acetaminophen could impede error-detection in the brain

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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