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U of M researchers receive grant to map senescent cells in preclinical studies and human tissues

Researchers at the University of Minnesota Medical School and the Institute on the Biology of Aging and Metabolism were awarded a total of $19.3 million in grants from the National Institutes of Health Common Fund to map senescent cells in preclinical studies and human tissues as part of the SenNet Consortium.

16 Sep 2022

Father of modern corneal science honored with the 2022 António Champalimaud Vision Award

Claes H. Dohlman, MD, PhD, whose pioneering research at Mass Eye and Ear and in the Department of Ophthalmology at Harvard Medical School (HMS) has forever changed the way conditions of the cornea are understood and treated, has been presented with the 2022 António Champalimaud Vision Award for his vast contributions to vision research.

15 Sep 2022

Lifestyle interventions can help pediatricians meet the growing need for youth depression management

With rising prevalence of depression in adolescents, screening requirements are increasingly falling on pediatric primary care providers, who are encountering more at-risk patients.

15 Sep 2022

Researchers join forces to 'map' specific variations in more than 25 key cardiac disease genes

One in 100 people have genetic variations that can cause potentially life-threatening heart conditions, including high cholesterol (lipid disorders), heart muscle disease (cardiomyopathies), and abnormal heart rhythms (arrhythmias).

13 Sep 2022

Study investigates the prevalence of adrenal tumors in an unselected screening population

A cross-sectional study of more than 25,000 adults has found that with increased screening, the prevalence of adrenal tumors in an unselected community population was 1.4%. The prevalence increased with age, from 0.2% in adults aged 18 to 25 up to 3.2% in adults older than 65 years of age. However, approximately 70% of identified tumors were nonfunctioning, meaning they did not make extra hormones, regardless of the participant's age. The findings are published in Annals of Internal Medicine.

13 Sep 2022

SARS-CoV-2 breakthrough infection in vaccinated individuals induces virus-specific nasal T cells of broad specificity

Long-lasting immune cells that specifically recognize the SARS-CoV-2 virus were found in the noses of people who were infected following vaccination.

12 Sep 2022

Blocking FNDC5 prevents cancer-induced cachexia in mice

The severe muscle atrophy and weakness commonly associated with cancer growth (i.e., cachexia) can be prevented simply by being deprived of FNDC5, the precursor of the exercise hormone irisin, researchers from the Indiana University School of Medicine have found.

12 Sep 2022

Exercise hormone reduces protein levels linked to Parkinson's disease

Researchers from Johns Hopkins Medicine and the Dana Farber Cancer Institute in Boston have shown that a hormone secreted into the blood during endurance, or aerobic, exercise reduces levels of a protein linked to Parkinson's disease and halts movement problems in mice.

12 Sep 2022

Kessler Foundation receives grant to continue the long-running "MS Fellowship in Neuropsychological Rehabilitation" program

John DeLuca, PhD, senior vice president of research and training at Kessler Foundation, received a five-year, $468,019 grant from the National Multiple Sclerosis Society to continue the long-running "MS Fellowship in Neuropsychological Rehabilitation" program.

9 Sep 2022

Study helps understand how dietary therapies work for epilepsy

Calorie restriction has long been associated with reduced seizures in epilepsy. New research from Boston Children's Hospital helps explain how fasting affects neurons in the brain and could lead the way to new approaches that would avoid the need for fasting or restrictive diets. The findings were published August 30 in the journal Cell Reports.

9 Sep 2022

Study provides some important new clues to age-related memory decline

One of the most upsetting aspects of age-related memory decline is not being able to remember the face that accompanies the name of a person you just talked with hours earlier.

8 Sep 2022

Novel 3D-printed light-sensing medical device could help millions of lupus patients

A team of engineers and doctors at the University of Minnesota Twin Cities have designed a unique 3D-printed light-sensing medical device that is placed directly on the skin and gives real-time feedback to correlate light exposure with disease flare-ups.

8 Sep 2022

Triplet therapy slows progression of advanced kidney cancer

A targeted kinase inhibitor added to a two-drug immunotherapy combination slowed the progression of advanced kidney cancer in previously untreated patients, according to research led by an oncologist from Dana-Farber Cancer Institute.

8 Sep 2022

New agonistic antibody reduced the amyloid pathology in mice with Alzheimer's disease

A newly developed agonistic antibody reduced the amyloid pathology in mice with Alzheimer's disease, signaling its promise as a potential treatment for the disease, according to a team of researchers at UTHealth Houston.

8 Sep 2022

Medical school-based culinary medicine programs seek to improve nutrition education

Culinary medicine programs are emerging at medical schools to meet a critical need to improve nutrition education in an era of unprecedented diet-related health problems including obesity and cardiovascular disease, according to a review of programs by UT Southwestern researchers published in Academic Medicine, the journal of the Association of American Medical Colleges.

7 Sep 2022

New tool uses artificial intelligence to calculate harmful effects of medicines

Research led by the University of Exeter and Kent and Medway NHS and Social Care Partnership Trust, published in Age and Ageing, assessed a new tool designed to calculate which medicines are more likely to experience adverse anticholinergic effects on the body and brain.

7 Sep 2022

Study: Number of babies born with cytomegalovirus decreased during the COVID-19 pandemic

Published in JAMA, University of Minnesota Medical School researchers discovered the number of babies born in Minnesota with cytomegalovirus (CMV) decreased significantly during the COVID-19 pandemic.

6 Sep 2022

Cooler ambient temperatures in the tropics increase risk of heart attacks

Scientists have long known that temperature changes impact the incidence of heart attacks. However, most of the research done so far has been in temperate climates, where temperatures range widely.

2 Sep 2022

Private equity ownership of physician practices may impose measures to squeeze out more profits, research says

New research reveals private equity firms that acquire physician-owned medical practices appear to be imposing measures to squeeze out more profits.

2 Sep 2022

Rutgers scientists design a synthetic protein that quickly detects molecules of deadly nerve agent

A team that includes Rutgers scientists has designed a synthetic protein that quickly detects molecules of a deadly nerve agent that has been classified by the United Nations as a weapon of mass destruction and could be used in a chemical warfare attack.

1 Sep 2022

Medical School News and Research

U of M researchers receive grant to map senescent cells in preclinical studies and human tissues

Father of modern corneal science honored with the 2022 António Champalimaud Vision Award

Lifestyle interventions can help pediatricians meet the growing need for youth depression management

Researchers join forces to 'map' specific variations in more than 25 key cardiac disease genes

Study investigates the prevalence of adrenal tumors in an unselected screening population

SARS-CoV-2 breakthrough infection in vaccinated individuals induces virus-specific nasal T cells of broad specificity

Blocking FNDC5 prevents cancer-induced cachexia in mice

Exercise hormone reduces protein levels linked to Parkinson's disease

Kessler Foundation receives grant to continue the long-running "MS Fellowship in Neuropsychological Rehabilitation" program

Study helps understand how dietary therapies work for epilepsy

Study provides some important new clues to age-related memory decline

Novel 3D-printed light-sensing medical device could help millions of lupus patients

Triplet therapy slows progression of advanced kidney cancer

New agonistic antibody reduced the amyloid pathology in mice with Alzheimer's disease

Medical school-based culinary medicine programs seek to improve nutrition education

New tool uses artificial intelligence to calculate harmful effects of medicines

Study: Number of babies born with cytomegalovirus decreased during the COVID-19 pandemic

Cooler ambient temperatures in the tropics increase risk of heart attacks

Private equity ownership of physician practices may impose measures to squeeze out more profits, research says

Rutgers scientists design a synthetic protein that quickly detects molecules of deadly nerve agent

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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