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New fly model developed to study motor neuron degeneration

Researchers at the Babraham Institute and University of Massachusetts Medical School in the United States have developed a new model to study motor neuron degeneration and have used this to identify three genes involved in the neurodegeneration process. These findings could have relevance for understanding the progression of amyotrophic lateral sclerosis (ALS) and other forms of motor neuron disease (MND).

7 Aug 2015

Einstein and Montefiore researchers receive $1.2 million grant to advance spinal cord injury research

Researchers at Albert Einstein College of Medicine and Montefiore Health System have received a $1.2 million grant from New York State to advance their promising technology for treating paralysis and other effects of spinal cord injuries (SCI).

7 Aug 2015

Brain-controlled prosthesis could improve quality of life in people with spinal cord injuries

When we type or perform other precise tasks, our brains and muscles usually work together effortlessly. But when a neurological disease or spinal cord injury severs the connection between the brain and limbs, once-easy motions become difficult or impossible.

3 Aug 2015

Study on marine snails could help better understand underlying mechanisms of age-related memory loss

A new research study on marine snails uncovered the first cells in the nervous system to fail during aging. The University of Miami Rosenstiel School of Marine and Atmospheric Science researchers' findings are important to better understanding the underlying mechanisms of age-related memory loss in humans.

30 Jul 2015

Mice without specific brain chemical develop characteristics similar to bipolar disorder, shows study

Mice that have a particular brain chemical switched off become hyperactive and sleep for just 65 per cent of their normal time.

29 Jul 2015

Static synapses that lie between cell body and AIS critical for decreasing neuronal excitability

In biology, stability is important. From body temperature to blood pressure and sugar levels, our body ensures that these remain within reasonable limits and do not reach potentially damaging extremes.

25 Jul 2015

Researchers use gene-editing technique involving low-dose irradiation to repair human stem cells

For the first time, researchers have employed a gene-editing technique involving low-dose irradiation to repair patient cells, according to a study published in the journal Stem Cells Translational Medicine. This method, developed by researchers in the Cedars-Sinai Board of Governors Regenerative Medicine Institute, is 10 times more effective than techniques currently in use.

23 Jul 2015

Key differences identified among patients with ALS

Researchers on Mayo Clinic's Florida campus have identified key differences between patients with sporadic amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease) and those with the most common genetic form of ALS, a mutation in the C9orf72 gene.

21 Jul 2015

Neuroscientists interpret code the brain uses to make noisy neuronal circuits

By analyzing the signals of individual neurons in animals undergoing behavioral tests, neuroscientists at Rice University, Baylor College of Medicine, the University of Geneva and the University of Rochester have deciphered the code the brain uses to make the most of its inherently "noisy" neuronal circuits.

17 Jul 2015

New project aims to revolutionize application of optogenetics in neuroscience

The revolution that optogenetics technology has brought to biology -- neuroscience in particular -- could be transformed all over again if a new project getting underway at Brown University and Central Michigan University is successful.

17 Jul 2015

Neuronal activity in the brain's prefrontal cortex is nuanced and complex, new study finds

Results of a new study reported this week by David Moorman of the University of Massachusetts Amherst and Gary Aston-Jones of Rutgers University suggest that adjusting behavior based on previous events involves an unexpected mix of neurons working together in the brain's prefrontal cortex.

17 Jul 2015

Scientists discover protein that plays significant role in development of fragile X syndrome

Scientists at VIB and KU Leuven have discovered that the protein APP plays a significant role in the development of fragile X syndrome (FXS) at young stages. They identified an unexpected biological pathway as a promising target to ameliorate deficits associated with FXS and autism. The results have recently been published in Neuron, one of the most influential journals in the field of neuroscience.

16 Jul 2015

New research offers potential for early intervention to prevent neurodegenerative diseases

New research led by investigators at Beth Israel Deaconess Medical Center provides the first direct evidence linking traumatic brain injury to Alzheimer's disease and chronic traumatic encephalopathy (CTE) -- and offers the potential for early intervention to prevent the development of these debilitating neurodegenerative diseases.

16 Jul 2015

Gene therapy provides life-long protection to photoreceptor cells in animal model of retinitis pigmentosa

A collaboration between scientists in the UK and the USA has shown that gene therapy can give life-long protection to the light-sensitive photoreceptor cells responsible for colour vision in a mouse model of the most common inherited eye disorder.

15 Jul 2015

Studies using MRI techniques can reveal brain connectivity differences in people with ASD

Studies using magnetic resonance imaging (MRI) techniques are beginning to reveal differences in brain connectivity--the ways that different parts of the brain are connected to each other and work together--in people with autism spectrum disorders (ASD), reports a review in the Harvard Review of Psychiatry.

15 Jul 2015

Salk professor receives Allen Distinguished Investigator award to uncover biology of Alzheimer's disease

The Salk Institute today announced that Rusty Gage, Salk professor in the Laboratory of Genetics, has been selected as one of five recipients of the Paul G. Allen Family Foundation's Allen Distinguished Investigator (ADI) program and will be awarded $1.5 million to conduct his research. These researchers have projects aimed at uncovering the elusive biological foundations of Alzheimer's disease.

15 Jul 2015

Paul G. Allen Family Foundation announces ADI grants for Alzheimer's disease research

The Paul G. Allen Family Foundation announced today the award of Allen Distinguished Investigator (ADI) grants to five teams of researchers with projects that will open new and innovative avenues of research in Alzheimer's disease by uncovering its elusive biological roots.

14 Jul 2015

Isis Pharmaceuticals receives $2.15 million milestone payment to advance ISIS-SMN Rx study in children with SMA

Isis Pharmaceuticals, Inc. announced today that it has earned a $2.15 million milestone payment from Biogen related to advancing the ongoing pivotal Phase 3 study (CHERISH) evaluating ISIS-SMN Rx in children with spinal muscular atrophy (SMA).

14 Jul 2015

SISSA scientists create synthetic enzymes that can differentiate between active and inactive genes

Certain genetic diseases arise from a deficit of specific genes. An enzyme that amplifies gene transcription could be a viable therapy in these cases, as long as genes are not stimulated to work on the wrong part of the body. SISSA scientists have created synthetic "intelligent" enzymes which are able to differentiate between active and inactive genes and selectively stimulate the former ones.

8 Jul 2015

Cedars-Sinai researchers test new methods for preserving cognition in laboratory mice

Cedars-Sinai researchers have successfully tested two new methods for preserving cognition in laboratory mice that exhibit features of Alzheimer's disease by using white blood cells from bone marrow and a drug for multiple sclerosis to control immune response in the brain.

8 Jul 2015

Neuron News and Research

New fly model developed to study motor neuron degeneration

Einstein and Montefiore researchers receive $1.2 million grant to advance spinal cord injury research

Brain-controlled prosthesis could improve quality of life in people with spinal cord injuries

Study on marine snails could help better understand underlying mechanisms of age-related memory loss

Mice without specific brain chemical develop characteristics similar to bipolar disorder, shows study

Static synapses that lie between cell body and AIS critical for decreasing neuronal excitability

Researchers use gene-editing technique involving low-dose irradiation to repair human stem cells

Key differences identified among patients with ALS

Neuroscientists interpret code the brain uses to make noisy neuronal circuits

New project aims to revolutionize application of optogenetics in neuroscience

Neuronal activity in the brain's prefrontal cortex is nuanced and complex, new study finds

Scientists discover protein that plays significant role in development of fragile X syndrome

New research offers potential for early intervention to prevent neurodegenerative diseases

Gene therapy provides life-long protection to photoreceptor cells in animal model of retinitis pigmentosa

Studies using MRI techniques can reveal brain connectivity differences in people with ASD

Salk professor receives Allen Distinguished Investigator award to uncover biology of Alzheimer's disease

Paul G. Allen Family Foundation announces ADI grants for Alzheimer's disease research

Isis Pharmaceuticals receives $2.15 million milestone payment to advance ISIS-SMN Rx study in children with SMA

SISSA scientists create synthetic enzymes that can differentiate between active and inactive genes

Cedars-Sinai researchers test new methods for preserving cognition in laboratory mice

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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