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Power grid failure inside injured cardiac cells triggers post-heart attack arrhythmias

Heart attack survivors often experience dangerous heart rhythm disturbances during treatment designed to restore blood flow to the injured heart muscle, a common and confounding complication of an otherwise lifesaving intervention.

9 Oct 2014

Higher doses of neuroleptics needed for pregnant women with psychiatric conditions

The new generation of neuroleptics for psychiatric conditions has the advantage over older medications of fewer adverse side effects. An investigation into their effectiveness in pregnant women has now discovered that higher doses are needed during pregnancy to maintain the desired effect.

9 Oct 2014

Online learning module for medical residents can improve care of substance use disorder patients

Online learning interventions and small group debriefings can improve medical residents' attitudes and communication skills toward patients with substance use disorders, and may result in improved care for these patients, according to a new study from the Perelman School of Medicine at the University of Pennsylvania and Drexel University College of Medicine published online in Academic Medicine.

9 Oct 2014

EPFL scientists discover two molecules that could overcome multidrug resistance in tuberculosis

Using a high-throughput screening assay, EPFL scientists have discovered two small molecules that could overcome the multidrug resistance of the bacterium that causes tuberculosis.

9 Oct 2014

Specific perceptual learning deficit associated with Fragile X Syndrome

Researchers at Children's Hospital Los Angeles have described for the first time a specific perceptual learning deficit in mice with a mutation of the same gene as found in children with Fragile X Syndrome (FXS).

9 Oct 2014

Viewpoints: Walmart's cuts in insurance grow from health law; online marketplace still lacks transparency

Wal-Mart gave lawmakers a concise lesson in economics Tuesday when it disclosed that it would no longer offer health insurance to yet more of its part-time employees. ... I'll just argue that what we're seeing is the entirely predictable result of the employer mandate in the 2010 Patient Protection and Affordable Care Act -- a mandate, by the way, that Wal-Mart lobbied for. The company was offering health benefits for most employees at the time, and may simply have been trying to force its competitors to do the same (Jon Healey, 10/7).

9 Oct 2014

Stiff rise in generic drug prices prompts probe by members of Congress

The prices have increased by more than 1,000 percent for some of the drugs. In other news about treatments, a study finds robotic surgery may not improve care for ovarian problems and the National Cancer Institute laments that insurers' concerns about cost are keeping some patients from proton therapy trials.

9 Oct 2014

TGen, NAU awarded patent for genomics-based test to detect H1N1 pandemic flu strain

The federal government has awarded a patent to the Translational Genomics Research Institute and Northern Arizona University for a test that can detect — and assist in the treatment of — the H1N1 pandemic flu strain.

9 Oct 2014

UCI to receive $8 million from NIH to study brain cell activity in motor neuron disorders

UC Irvine will receive $8 million from the National Institutes of Health to establish one of six national centers dedicated to creating a database of human cellular responses that will accelerate efforts to develop new therapies for many diseases.

9 Oct 2014

CMS directs insurers to begin testing healthcare.gov but maintain confidentiality

Testers are required to "acknowledge the confidentiality of the process" in order to gain access to the testing environment, according to The Wall Street Journal. Meanwhile, The New York Times reports on two studies that examine the health law's drug plans as a means to answer questions about how the overhaul is working.

9 Oct 2014

Researchers generate fruit fly model, unveil key genetic factors behind human colon cancer

Researchers at the Institute for Research in Biomedicine (IRB Barcelona) have managed to generate a fruit fly (Drosophila melanogaster) model that reproduces human colon cancer. With two publications appearing in PLoS One and EMBO Reports, the IRB team also unveil the function of a key gene in the development of the disease.

9 Oct 2014

Pointers for boosting prophylactic bipolar treatment reported

Patients with newly diagnosed bipolar disorder who have not previously used psychiatric drugs or have short hospital admissions should be targeted for prophylactic treatment, say researchers.

8 Oct 2014

Large-scale study results of cardiac arrest cases now available on ScienceDirect

The results of a four-year international study of 2060 cardiac arrest cases across 15 hospitals published and available now on ScienceDirect.

8 Oct 2014

Researchers use computer based predictions to combat AIDS

The battle against AIDS cannot be won in the laboratory alone. To fight the potentially deadly virus that 34 million people are suffering from we need help from computers.

8 Oct 2014

Boehringer Ingelheim announces availability of Striverdi Respimat Inhalation Spray 5 mcg in the U.S.

Boehringer Ingelheim today announced that Striverdi Respimat (olodaterol) Inhalation Spray 5 mcg is now available by prescription in pharmacies across the United States.

8 Oct 2014

MicroRNA molecule plays crucial role in managing cell survival and growth

Researchers at the University of California, San Diego School of Medicine have identified a microRNA molecule as a surprisingly crucial player in managing cell survival and growth.

8 Oct 2014

Gerresheimer Q3 revenues up 2.2% to EUR 323.9m

Gerresheimer AG again increased revenues in the third quarter of financial year 2014.

8 Oct 2014

FDA grants QIDP and Fast Track designation to Nabriva's lefamulin for treatment of CABP, ABSSSI

Nabriva Therapeutics AG, a biotechnology company focused on developing pleuromutilins, a new class of antibiotics for the treatment of serious infections caused by resistant Gram-positive and Gram-negative pathogens, announced today that the United States Food and Drug Administration has granted Qualified Infectious Disease Product (QIDP) as well as Fast Track status designation to Nabriva's lead product lefamulin, for the treatment of community-acquired bacterial pneumonia (CABP) and acute bacterial skin and skin structure infections (ABSSSI).

8 Oct 2014

Finesse Solutions launches SmartFactory for single-use facilities

Finesse Solutions, Inc., Santa Clara, CA, a manufacturer of measurement and control solutions for life sciences process applications, announced the launch of SmartFactory, which is a uniquely configurable design architecture for single-use facilities.

8 Oct 2014

Case Western Reserve researcher lands Director's New Innovator Awards from NIH

For the second consecutive year, a Case Western Reserve University School of Medicine researcher has landed one of the year's much-coveted Director's New Innovator Awards from the National Institutes of Health. Principal investigator Rong Xu, PhD, assistant professor of medical informatics, will receive $2,377,000 for five years, starting immediately, to initiate computational analysis of thousands of drugs and their effects.

8 Oct 2014

Drugs News and Research

Power grid failure inside injured cardiac cells triggers post-heart attack arrhythmias

Higher doses of neuroleptics needed for pregnant women with psychiatric conditions

Online learning module for medical residents can improve care of substance use disorder patients

EPFL scientists discover two molecules that could overcome multidrug resistance in tuberculosis

Specific perceptual learning deficit associated with Fragile X Syndrome

Viewpoints: Walmart's cuts in insurance grow from health law; online marketplace still lacks transparency

Stiff rise in generic drug prices prompts probe by members of Congress

TGen, NAU awarded patent for genomics-based test to detect H1N1 pandemic flu strain

UCI to receive $8 million from NIH to study brain cell activity in motor neuron disorders

CMS directs insurers to begin testing healthcare.gov but maintain confidentiality

Researchers generate fruit fly model, unveil key genetic factors behind human colon cancer

Pointers for boosting prophylactic bipolar treatment reported

Large-scale study results of cardiac arrest cases now available on ScienceDirect

Researchers use computer based predictions to combat AIDS

Boehringer Ingelheim announces availability of Striverdi Respimat Inhalation Spray 5 mcg in the U.S.

MicroRNA molecule plays crucial role in managing cell survival and growth

Gerresheimer Q3 revenues up 2.2% to EUR 323.9m

FDA grants QIDP and Fast Track designation to Nabriva's lefamulin for treatment of CABP, ABSSSI

Finesse Solutions launches SmartFactory for single-use facilities

Case Western Reserve researcher lands Director's New Innovator Awards from NIH

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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