Genetic News and Research

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Alnylam begins dosing in Phase I clinical trial with ALN-TTRsc for treatment of ATTR

Alnylam Pharmaceuticals a leading RNAi therapeutics company, announced today that it has initiated dosing in its Phase I clinical trial with ALN-TTRsc, an RNAi therapeutic targeting transthyretin (TTR) for the treatment of TTR-mediated amyloidosis (ATTR).

19 Mar 2013

A Map of 'Shortcuts' simplifies the hunt for disease-causing genes

Some diseases are caused by single gene mutations. Current techniques for identifying the disease-causing gene in a patient produce hundreds of potential gene candidates, making it difficult for scientists to pinpoint the single causative gene.

19 Mar 2013

Research provides better understanding of microbiological factors of periodontitis

Microbes from the human mouth are telling Oak Ridge National Laboratory scientists something about periodontitis and more after they cracked the genetic code of bacteria linked to the condition.

19 Mar 2013

Research reveals immortality gene mutation plays pivotal role in brain tumors, other cancers

Newly identified mutations in a gene that makes cells immortal appear to play a pivotal role in three of the most common types of brain tumors, as well as cancers of the liver, tongue and urinary tract, according to research led by Duke Cancer Institute.

19 Mar 2013

Online chat rooms provide beneficial forum for chronic pain sufferers

The more than 100 million Americans living with chronic pain and daily suffering often have limited outlets to talk about their conditions with others who can understand and offer comfort. Online chatrooms may provide a beneficial forum where chronic pain sufferers can openly and safely communicate, as discussed in an article in Cyberpsychology, Behavior, and Social Networking, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

19 Mar 2013

Controlling hypertension earlier in life may limit brain changes associated with Alzheimer's disease

A study in the JAMA Neurology (formerly the Archives of Neurology) suggests that controlling or preventing risk factors such as hypertension earlier in life may limit or delay the brain changes associated with Alzheimer's disease and other age-related neurological deterioration.

19 Mar 2013

N.D. lawmakers pass 'heartbeat' abortion ban

North Dakota lawmakers have passed a bill that would ban abortions there, with few exceptions, after a fetal heartbeat can be detected -- after about six weeks. The ban would one of the most restrictive abortion laws in the nation.

19 Mar 2013

Columbia University Medical Center, NewYork-Presbyterian Hospital present research works at AAN meeting

The following research from Columbia University Medical Center and NewYork-Presbyterian Hospital is being presented at the 65th annual meeting of the American Academy of Neurology, March 16-23, 2013, in San Diego.

18 Mar 2013

Researchers find white blood cells produce and eliminate RBCs

Researchers at Albert Einstein College of Medicine of Yeshiva University and the Icahn School of Medicine at Mount Sinai have found that macrophages - white blood cells that play a key role in the immune response - also help to both produce and eliminate the body's red blood cells (RBCs).

18 Mar 2013

UCLA researchers predict hotspots for future outbreaks of influenza virus

This year's unusually long and rocky flu season would be nothing compared to the pandemic that could occur if bird flu became highly contagious among humans, which is why UCLA researchers and their colleagues are creating new ways to predict where an outbreak could emerge.

17 Mar 2013

New molecular sensor technique for cancer therapy detects lactate levels in individual cells

Cancer cells break down sugars and produce the metabolic acid lactate at a much higher rate than normal cells. This phenomenon provides a telltale sign that cancer is present, via diagnostics such as PET scans, and possibly offers an avenue for novel cancer therapies.

16 Mar 2013

Genetic score based on PCa risk-associated SNPs predicts prostate biopsy outcomes: Study

A genetic score based on PCa risk-associated single nucleotide polymorphisms is an independent predictor of prostate biopsy outcomes, suggest the results of a new study conducted by a group from the Department of Urology Huashan Hospital, Fudan University in Shanghai, China.

16 Mar 2013

Researchers identifiy elusive anti-cancer property of vitamin E

Researchers have identified an elusive anti-cancer property of vitamin E that has long been presumed to exist, but difficult to find. Many animal studies have suggested that vitamin E could prevent cancer, but human clinical trials following up on those findings have not shown the same benefits.

16 Mar 2013

Discovery could lead to new target for treatment of cocaine addiction

Scientists have discovered a molecular process in the brain triggered by cocaine use that could provide a target for treatments to prevent or reverse addiction to the drug.

16 Mar 2013

Historical review provides lessons for control of plague

Today archaeologists unearthed a 'Black Death' grave in London, containing more than a dozen skeletons of people suspected to have died from the plague. The victims are thought to have died during the 14th century and archaeologists anticipate finding many more as they excavate the site.

16 Mar 2013

Research suggests depression can increase risk of heart problems later in life

Teens who were depressed as children are far more likely than their peers to be obese, smoke cigarettes and lead sedentary lives, even if they no longer suffer from depression.

16 Mar 2013

Research shows changes in mouse coat color were the result of nine mutations within a single gene

For deer mice living in the Nebraska Sandhills, color can literally be the difference between life and death. When they first colonized the region, the dark-coated mice stood out starkly against the light-colored, sandy soil, making them easy prey for predators.

15 Mar 2013

Researchers receive AHRF grant to investigate genetic hearing screening program for newborns

Researchers at the Medical College of Wisconsin in Milwaukee, Wisconsin, have received a grant from the American Hearing Research Foundation to conduct a pilot study of genetic hearing screening for newborns at the Children's Hospital of Wisconsin to ensure the test can be performed and results shared with the parents in a timely and meaningful way.

15 Mar 2013

New hunt for intrinsic mechanism linked to schizophrenia

Since the 1960s, psychiatrists have been hunting for substances made by the body that might accumulate in abnormally high levels to produce the symptoms associated with schizophrenia. In particular, there was a search for chemicals that might be related to the hallucinogens phencyclidine (PCP) or lysergic acid diethylamide (LSD), which could explain the emergence of psychotic symptoms in schizophrenia.

15 Mar 2013

Researchers identify enzymes that activate coronavirus for infection

Scientists all over the world are on a quest for an antidote since the first patient died from the new coronavirus in summer 2012. Infection Researchers from the German Primate Center have now identified enzymes that activate the virus for infection.

15 Mar 2013

Genetic News and Research

Alnylam begins dosing in Phase I clinical trial with ALN-TTRsc for treatment of ATTR

A Map of 'Shortcuts' simplifies the hunt for disease-causing genes

Research provides better understanding of microbiological factors of periodontitis

Research reveals immortality gene mutation plays pivotal role in brain tumors, other cancers

Online chat rooms provide beneficial forum for chronic pain sufferers

Controlling hypertension earlier in life may limit brain changes associated with Alzheimer's disease

N.D. lawmakers pass 'heartbeat' abortion ban

Columbia University Medical Center, NewYork-Presbyterian Hospital present research works at AAN meeting

Researchers find white blood cells produce and eliminate RBCs

UCLA researchers predict hotspots for future outbreaks of influenza virus

New molecular sensor technique for cancer therapy detects lactate levels in individual cells

Genetic score based on PCa risk-associated SNPs predicts prostate biopsy outcomes: Study

Researchers identifiy elusive anti-cancer property of vitamin E

Discovery could lead to new target for treatment of cocaine addiction

Historical review provides lessons for control of plague

Research suggests depression can increase risk of heart problems later in life

Research shows changes in mouse coat color were the result of nine mutations within a single gene

Researchers receive AHRF grant to investigate genetic hearing screening program for newborns

New hunt for intrinsic mechanism linked to schizophrenia

Researchers identify enzymes that activate coronavirus for infection

Genetics & Genomics - Second Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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