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Trastuzumab offers better outcome than lapatinib for HER2-positive breast cancer patients

Analysis of more than 8,000 women who participated in the world's largest study of two treatments for HER2-positive breast cancer reinforces other findings from the clinical trial showing that trastuzumab (Herceptin) should remain the standard of care for this cancer, says a Mayo Clinic researcher.

30 Sep 2014

UCSF gets CDC grant to provide expert guidance to clinicians who prescribe anti-HIV medications

The UCSF Clinician Consultation Center at San Francisco General Hospital and Trauma Center has been funded by the Centers for Disease Control and Prevention to provide a PrEPline, a telephone consultation service that gives expert guidance to healthcare providers across the nation who prescribe antiretroviral medications to HIV uninfected individuals to prevent HIV.

30 Sep 2014

AAN releases new position statement on opioids for chronic non-cancer pain

According to a new position statement from the American Academy of Neurology, the risk of death, overdose, addiction or serious side effects with prescription opioids outweigh the benefits in chronic, non-cancer conditions such as headache, fibromyalgia and chronic low back pain.

30 Sep 2014

Cedars-Sinai experts to present free conference on dystonia for patients, families and caregivers

A multidisciplinary team of experts affiliated with the Cedars-Sinai Movement Disorders Program will present a free conference for patients, families and caregivers on treatment options for dystonia, which causes painful and potentially crippling muscle contractions.

30 Sep 2014

VCU receives $6 million grant to develop safe, effective treatments for cocaine addiction

Virginia Commonwealth University has received a five-year, $6 million grant for clinical research and education directed toward the identification, evaluation and development of safe and effective treatments for cocaine addiction.

30 Sep 2014

Three institutions collaborate to study genetics of bipolar disorder, schizophrenia

Researchers at the University of Michigan School of Public Health and Medical School and collaborators at two other institutions will undertake the largest whole genome sequencing study funded to date, as they seek to better understand bipolar disorder and schizophrenia.

30 Sep 2014

Phase 3 COU-AA-302 results show ZYTIGA plus prednisone prolongs overall survival in men with chemotherapy-naive mCRPC

A final analysis of the Phase 3 COU-AA-302 trial presented today at the European Society for Medical Oncology (ESMO) 2014 Congress in Madrid, Spain showed that ZYTIGA® (abiraterone acetate) plus prednisone significantly prolonged overall survival (OS), compared to an active control of placebo plus prednisone, in men with chemotherapy-naive metastatic castration-resistant prostate cancer (mCRPC).

30 Sep 2014

Researchers explain how molecular structure of the heart muscle changes in heart failure

In a new study published in Proceedings of the National Academy of Sciences USA, researchers at the University of Alberta's Faculty of Medicine & Dentistry have explained how the function of a key protein in the heart changes in heart failure.

30 Sep 2014

State highlights: Calif. health insurers and contraception coverage; Alaska sues Xerox over Medicaid payment systems

Health insurance policies in California will have to cover all federally approved contraceptives for women by 2016 without charging co-payments under legislation signed this week by Gov. Jerry Brown, countering trends in other states and the U.S. Supreme Court. The bill, SB1053 by Sen. Holly Mitchell, D-Los Angeles, expands state laws that required coverage for most birth-control drugs and devices approved by the U.S. Food and Drug Administration. The new law mandates coverage for all FDA-approved contraception, prohibits co-payments and includes managed-care Medi-Cal plans, which are not expressly covered by current laws (Egelko, 9/27).

30 Sep 2014

Nivolumab drug achieves superior response rates in previously-treated advanced melanoma patients

The monoclonal antibody nivolumab achieves superior response rates and a longer duration of response than standard chemotherapy in patients whose melanoma has progressed after treatment with ipilimumab, according to phase III data presented at the ESMO 2014 Congress in Madrid, Spain.

30 Sep 2014

Combination therapy achieves greater progression-free survival, response rates in melanoma

Combination therapy with both BRAF inhibitor vemurafenib and MEK inhibitor cobimetinib achieves greater progression-free survival and response rates than vemurafenib plus placebo in BRAF-mutation positive melanoma, according to phase III data presented at the ESMO 2014 Congress in Madrid, Spain.

30 Sep 2014

New approach to solve global challenges in food security, emerging diseases and biodiversity loss

Solving global challenges in food security, emerging diseases and biodiversity loss requires evolutionary thinking, argues a new study published online in Science Express that was co-authored by Bruce Tabashnik of the University of Arizona College of Agriculture and Life Sciences.

30 Sep 2014

Apexus secures HRSA contract, continues to serve as prime vendor of 340B Drug Pricing Program

Apexus, LLC, the prime vendor for the 340B Drug Pricing Program, has announced that it has been selected by the Health Resources and Services Administration (HRSA) to continue serving in its role as the prime vendor through September 29, 2019.

30 Sep 2014

Antibiotic exposure in infancy linked to childhood obesity

Repeated exposure to broad-spectrum antibiotics in the first two years of life is associated with early childhood obesity, say researchers from The Children's Hospital of Philadelphia in a retrospective study based on data from electronic health records from the extensive CHOP Care Network.

30 Sep 2014

Targeted combination drug therapy can extend life, halt disease in metastatic melanoma patients

A world-first study in today's New England Journal of Medicine heralds the efficacy of a targeted combination drug therapy after reporting major declines in the risk of disease progression and death in people with metastatic melanoma.

29 Sep 2014

Drugmakers boost generic drug prices

A big increase in generic drug prices is forcing some patients to go without, reports CBS Boston. Meanwhile, U.S. News & World Report teases out some of the reasons for the slowdown in health care costs.

29 Sep 2014

Christiana Care Health System wins 2014 Health Devices Achievement Award

ECRI Institute is pleased to announce Christiana Care Health System, Wilmington, DE, as the winner of its 9th Annual Health Devices Achievement Award.

29 Sep 2014

Avanir Pharmaceuticals closes public offering of 20,930,000 shares of common stock

Avanir Pharmaceuticals, Inc. today announced the closing of its previously announced public offering of 20,930,000 shares of its common stock, including 2,730,000 shares sold pursuant to the underwriters' full exercise of their option to purchase additional shares, at a price to the public of $11.00 per share, before underwriting discounts.

29 Sep 2014

Spring Mountain Capital leads financing round for Oncoceutics with additional private investors' participation

Spring Mountain Capital, LP, a New York-based investment management firm, announced today that its private equity group structured and led a financing round for Oncoceutics, Inc. with additional private investors' participation.

29 Sep 2014

Aptose joins Beat AML research collaboration

Aptose Biosciences Inc., a clinical-stage company developing new therapeutics and molecular diagnostics that target the underlying mechanisms of cancer, the Knight Cancer Institute at Oregon Health & Science University and The Leukemia & Lymphoma Society today announced that Aptose has joined the Beat AML collaboration.

29 Sep 2014

Drugs News and Research

Trastuzumab offers better outcome than lapatinib for HER2-positive breast cancer patients

UCSF gets CDC grant to provide expert guidance to clinicians who prescribe anti-HIV medications

AAN releases new position statement on opioids for chronic non-cancer pain

Cedars-Sinai experts to present free conference on dystonia for patients, families and caregivers

VCU receives $6 million grant to develop safe, effective treatments for cocaine addiction

Three institutions collaborate to study genetics of bipolar disorder, schizophrenia

Phase 3 COU-AA-302 results show ZYTIGA plus prednisone prolongs overall survival in men with chemotherapy-naive mCRPC

Researchers explain how molecular structure of the heart muscle changes in heart failure

State highlights: Calif. health insurers and contraception coverage; Alaska sues Xerox over Medicaid payment systems

Nivolumab drug achieves superior response rates in previously-treated advanced melanoma patients

Combination therapy achieves greater progression-free survival, response rates in melanoma

New approach to solve global challenges in food security, emerging diseases and biodiversity loss

Apexus secures HRSA contract, continues to serve as prime vendor of 340B Drug Pricing Program

Antibiotic exposure in infancy linked to childhood obesity

Targeted combination drug therapy can extend life, halt disease in metastatic melanoma patients

Drugmakers boost generic drug prices

Christiana Care Health System wins 2014 Health Devices Achievement Award

Avanir Pharmaceuticals closes public offering of 20,930,000 shares of common stock

Spring Mountain Capital leads financing round for Oncoceutics with additional private investors' participation

Aptose joins Beat AML research collaboration

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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