Drugs News and Research

RSS

Myriad Genetics' Tumor BRACAnalysis CDx identifies 44% more candidates for PARP therapy

Myriad Genetics, Inc. today announced that its Tumor BRACAnalysis CDx- companion diagnostic test significantly improved the detection of cancer-causing BRCA1/2 mutations by 44 percent in women with ovarian cancer. Data from this new study were presented at the 2014 European Society for Medical Oncology annual meeting in Madrid, Spain.

29 Sep 2014

Scientists discover mechanism that resists cancer drugs in estrogen-positive breast cancer

Scientists have discovered a previously unknown mechanism by which estrogen prepares cells to divide, grow and, in the case of estrogen-positive breast cancers, resist cancer drugs. The researchers say the work reveals new targets for breast cancer therapy and will help doctors predict which patients need the most aggressive treatment.

29 Sep 2014

Lung-MAP, ALCHEMIST clinical trials offer innovative study designs for lung cancer patients

The recent launch of two clinical trials offer innovative study designs for patients with lung cancer. These clinical trials are the direct result of a National Cancer Institute sponsored workshop chaired by Drs. Fred R. Hirsch, Shakun Malik and Claudio Dansky- Ullman, that brought together the NCI Thoracic Malignancies Steering Committee, the US Food and Drug Administration, academicians, clinicians as well as industry and government stakeholders to discuss issues and challenges related to clinical trial design and biomarkers for lung cancer targeted-therapies.

29 Sep 2014

Anamorelin drug safe and well tolerated in advanced non-small cell lung cancer, Phase III trial reveals

A new drug, anamorelin, improves appetite and body mass in patients with advanced lung cancer who are suffering cancer anorexia and cachexia, according to phase III data presented at the ESMO 2014 Congress in Madrid, Spain.

29 Sep 2014

Crizotinib drug effectively halts growth of ROS1-positive lung tumors

Treatment with the targeted therapy drug crizotinib effectively halts the growth of lung tumors driven by rearrangements of the ROS1 gene. In an article receiving Online First publication in the New England Journal of Medicine to coincide with a presentation at the European Society for Medical Oncology meeting, an international research team reports that crizotinib treatment led to significant tumor shrinkage in 36 of 50 study participants and suppressed tumor growth in another 9.

29 Sep 2014

NJHF awards grant to help launch drug discovery facility at Rutgers University

In its continuing effort to advance the biomedical sciences, New Jersey Health Foundation has awarded a pivotal $35,000 grant to the Office of Translational Sciences at Rutgers, The State University of New Jersey, to help launch a Fragment Based Drug Discovery (FBDD) core facility.

29 Sep 2014

Daiichi Sankyo, Ambit Biosciences enter into definitive merger agreement

Daiichi Sankyo Company, Ltd. (hereinafter Daiichi Sankyo) and Ambit Biosciences, jointly announced today that they have entered into a definitive merger agreement under which Daiichi Sankyo will acquire all of the outstanding common stock of Ambit Biosciences for $15 per share in cash through a tender offer followed by a merger with a subsidiary of Daiichi Sankyo, or approximately $315 million on a fully diluted basis.

29 Sep 2014

State highlights: Calif. gov. vetoes bill limiting Medi-Cal estate recovery, signs birth control, inmate bills

In a blow to tens of thousands of low-income Californians newly enrolled in Medi-Cal under a provision in the Affordable Care Act, Gov. Jerry Brown on Thursday vetoed a bill that would have limited the state's seizure of assets from their estates after they die -- a legal wrinkle that most only discovered after they had signed up for the health care plan for the poor (Seipel, 9/25).

27 Sep 2014

Viewpoints: 'Feud' over health care compact; humane end-of-life care

Never has an issue of The Best Times, Johnson County's monthly magazine for seniors, been so eagerly awaited. I know I've been on the edge of my seat. At first the draw was to read the article that had gotten some Kansas legislators so worked up that 11 of them stormed en masse into a meeting to berate the volunteer members of the Johnson County Commission on Aging for writing it.

27 Sep 2014

MIT researchers use disarmed version of anthrax toxin to deliver cancer drugs

Bacillus anthracis bacteria have very efficient machinery for injecting toxic proteins into cells, leading to the potentially deadly infection known as anthrax. A team of MIT researchers has now hijacked that delivery system for a different purpose: administering cancer drugs.

26 Sep 2014

Imperial scientists map proteins affected by NMT enzyme, suggest potential way to treat cancer

Imperial chemists have gained fresh insights into how a disease-causing enzyme makes changes to proteins and how it can be stopped.

26 Sep 2014

Australian researchers use hookworms to reduce symptoms of celiac disease

Australian researchers have achieved groundbreaking results in a clinical trial using hookworms to reduce the symptoms of celiac disease.

26 Sep 2014

Researchers develop new strategy for reducing serious side effects of modern anticancer drugs

An interdisciplinary team of researchers from the University of Vienna (Institute of Inorganic Chemistry) and the Medical University of Vienna (Institute for Cancer Research) has successfully developed a new strategy for reducing the often serious side effects of an important class of modern anticancer drugs (tyrosine kinase inhibitors).

26 Sep 2014

Scientists discover new clues about drug used in treating blood cancer

Keck Medicine of USC scientists have discovered new clues about a drug instrumental in treating a certain blood cancer that may provide important targets for researchers searching for cures.

26 Sep 2014

Access to potentially life-extending cancer drugs varies worldwide

Access to potentially life-extending cancer drugs varies significantly in different regions of the world, two new studies show at the ESMO 2014 Congress in Madrid, Spain.

26 Sep 2014

Sumitomo Dainippon Pharma, SanBio to jointly develop SB623 in the U.S. and Canada

Sumitomo Dainippon Pharma Co., Ltd. and SanBio Co., Ltd., acting through its U.S. subsidiary SanBio, Inc., announced on September 26 that the two companies have entered into a joint development and license agreement for exclusive marketing rights in the U.S. and Canada ("Agreement") for SB623, a cell therapy for the treatment of patients with chronic stroke discovered and currently under development by SanBio.

26 Sep 2014

Thirteen research projects to explore nondrug approaches to manage pain, other health conditions

Thirteen research projects totaling approximately $21.7 million over 5 years will explore nondrug approaches to managing pain and related health conditions such as post-traumatic stress disorder (PTSD), drug abuse, and sleep issues. The effort seeks to enhance options for the management of pain and associated problems in U.S. military personnel, veterans, and their families.

26 Sep 2014

Longer looks: ACOs and job shifts; abortion's racial gap; having a stroke at 33

It is now nearly a year since the roll-out of Obamacare. The launch was a shambles, and Obamacare is a totem for every American who hates big government. Republicans will deride it, yet again, in the mid-term elections. Obamacare is indeed costly and overcomplicated. Yet it is not to blame for America's health mess, and it could just contain the beginnings of a partial solution to it. But that will only happen if politicians treat health care like a patient: first, diagnose the disease, then examine whether Barack Obama's treatment helped, and then ask what will make the patient better (9/20).

26 Sep 2014

Researchers awarded $16 million NIMH grant to create genetic resource for psychiatric disorders

A multi-institutional team of researchers studying schizophrenia and bipolar disorder has been awarded a $16 million grant from the National Institute of Mental Health to create the most extensive genetic resource to date for these two devastating psychiatric disorders, using data assembled by the University of Southern California.

26 Sep 2014

Study findings have potential to advance treatments for small cell lung cell cancer

Two recently published studies by a research team at University Hospitals Case Medical Center Seidman Cancer Center have the potential to advance treatments for small cell lung cell cancer (SCLC). This aggressive form of lung cancer has seen no treatment advances in 30 years and "is a disease in urgent need of new drug therapies," write the study's authors.

26 Sep 2014

Drugs News and Research

Myriad Genetics' Tumor BRACAnalysis CDx identifies 44% more candidates for PARP therapy

Scientists discover mechanism that resists cancer drugs in estrogen-positive breast cancer

Lung-MAP, ALCHEMIST clinical trials offer innovative study designs for lung cancer patients

Anamorelin drug safe and well tolerated in advanced non-small cell lung cancer, Phase III trial reveals

Crizotinib drug effectively halts growth of ROS1-positive lung tumors

NJHF awards grant to help launch drug discovery facility at Rutgers University

Daiichi Sankyo, Ambit Biosciences enter into definitive merger agreement

State highlights: Calif. gov. vetoes bill limiting Medi-Cal estate recovery, signs birth control, inmate bills

Viewpoints: 'Feud' over health care compact; humane end-of-life care

MIT researchers use disarmed version of anthrax toxin to deliver cancer drugs

Imperial scientists map proteins affected by NMT enzyme, suggest potential way to treat cancer

Australian researchers use hookworms to reduce symptoms of celiac disease

Researchers develop new strategy for reducing serious side effects of modern anticancer drugs

Scientists discover new clues about drug used in treating blood cancer

Access to potentially life-extending cancer drugs varies worldwide

Sumitomo Dainippon Pharma, SanBio to jointly develop SB623 in the U.S. and Canada

Thirteen research projects to explore nondrug approaches to manage pain, other health conditions

Longer looks: ACOs and job shifts; abortion's racial gap; having a stroke at 33

Researchers awarded $16 million NIMH grant to create genetic resource for psychiatric disorders

Study findings have potential to advance treatments for small cell lung cell cancer

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Latest News