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Newborn screening can prevent lifelong disability

When your baby was born you likely heard a loud cry and examined your baby to make sure he/she had a full set of adorable fingers and toes. But just imagine a few days after you arrive home, your phone rings: your baby has screened positive for a genetic disorder.

24 Sep 2014

Tissue-level model of human airway musculature could pave way for patient-specific asthma treatments

The majority of drugs used to treat asthma today are the same ones that were used 50 years ago. New drugs are urgently needed to treat this chronic respiratory disease, which causes nearly 25 million people in the United States alone to wheeze, cough, and find it difficult at best to take a deep breath.

24 Sep 2014

UW-Madison and Morgridge researchers are creating tissue chip technology to screen neural toxins

A multidisciplinary team at the University of Wisconsin-Madison and the Morgridge Institute for Research is creating a faster, more affordable way to screen for neural toxins, helping flag chemicals that may harm human development.

24 Sep 2014

Alectinib promise for crizotinib-resistant NSCLC

Alectinib has shown promising antitumour activity in patients with ALK-rearranged non-small-cell lung cancer that is resistant to crizotinib, researchers report.

23 Sep 2014

Blocking AEG-1 gene expression halts development of liver cancer by regulating inflammation

Inflammation has been shown to be a driving force behind many chronic diseases, especially liver cancer, which often develops due to chronic inflammation caused by conditions such as viral hepatitis or alcoholism and has relatively few effective treatment options.

23 Sep 2014

KemPharm to initiate clinical trials in Canada for lead product candidate KP201

KemPharm, Inc., a clinical-stage specialty pharmaceutical company engaged in the discovery and development of proprietary new molecular entity (NME) prodrugs, announced today that it received a No Objection Letter (NOL) from Health Canada to begin clinical trials in Canada for its lead product candidate KP201 (benzhydrocodone hydrochloride and acetaminophen)

23 Sep 2014

Cedars-Sinai scientists test ELAD bioartificial liver support system for patients with acute liver failure

Cedars-Sinai physicians and scientists are testing a novel, human cell based, bioartificial liver support system for patients with acute liver failure, often a fatal diagnosis.

23 Sep 2014

Enable Injections named winner of 'Buzz of BIO Investor Forum' contest

Enable Injections, developer of a novel wearable 'bolus injector' that may soon make it easy and nearly painless for patients to self-inject large-dose biologic drugs in the comfort of their homes, has been named winner of the 'Buzz of BIO Investor Forum' contest recognizing highly innovative companies in the biotech sector.

23 Sep 2014

New evidence-based guidelines for prevention, treatment of POAF

The American Association for Thoracic Surgery has released new evidence-based guidelines for the prevention and treatment of perioperative and postoperative atrial fibrillation (POAF) and flutter for thoracic surgical procedures.

23 Sep 2014

Promising new approach for combating colorectal cancer

Scientists at the University of York are working on a promising new approach for tackling colorectal cancer, the second most common cause of cancer-related death.

23 Sep 2014

Caltech researcher explores link between variable heart rate, health and fitness

Although the heart beats out a very familiar "lub-dub" pattern that speeds up or slows down as our activity increases or decreases, the pattern itself isn't as regular as you might think. In fact, the amount of time between heartbeats can vary even at a "constant" heart rate-and that variability, doctors have found, is a good thing.

23 Sep 2014

Researchers develop T-MOC device to study complex environment surrounding tumors

Researchers have developed a chip capable of simulating a tumor's "microenvironment" and plan to use the new system to test the effectiveness of nanoparticles and drugs that target cancer.

23 Sep 2014

Immature blood vessels linked to poor sunitinib response

Patients with clear-cell renal cell carcinoma with relatively mature blood vessels respond better to sunitinib and have fewer metastatic sites than those with immature vessels, a study has found.

22 Sep 2014

Amgen seeks FDA approval for leukemia drug blinatumomab

Amgen today announced submission of a Biologics License Application (BLA) to the U.S. Food and Drug Administration seeking approval for its investigational bispecific T cell engager (BiTE) antibody construct, blinatumomab.

22 Sep 2014

C-Path renews grant to advance more effective drug treatments for TB

The Critical Path Institute, an independent, non-profit organization that works to accelerate the speed of drug and medical product development, today announced it has received a three-year grant renewal from the Bill & Melinda Gates Foundation.

22 Sep 2014

Phase IIa clinical trial data of ATL1102 in MS patients published in journal Neurology

Antisense Therapeutics is pleased to report the publication of previously generated Phase IIa clinical trial data on ATL1102 in the medical journal Neurology.

22 Sep 2014

MIT engineers find new strategy to combat superbugs

In recent years, new strains of bacteria have emerged that resist even the most powerful antibiotics. Each year, these superbugs, including drug-resistant forms of tuberculosis and staphylococcus, infect more than 2 million people nationwide, and kill at least 23,000. Despite the urgent need for new treatments, scientists have discovered very few new classes of antibiotics in the past decade.

22 Sep 2014

New study sheds light on longstanding question about role of mitochondria in motor neuron diseases

A new study by researchers at the University of Utah School of Medicine sheds light on a longstanding question about the role of mitochondria in debilitating and fatal motor neuron diseases and resulted in a new mouse model to study such illnesses.

22 Sep 2014

EYLEA Injection gets approval in Japan for treatment of myopic CNV

Regeneron Pharmaceuticals, Inc. today announced that Bayer HealthCare's Japanese subsidiary, Bayer Yakuhin, Ltd. has received approval from the Japanese Ministry of Health, Labour and Welfare for EYLEA (aflibercept) Injection for myopic choroidal neovascularization (myopic CNV).

22 Sep 2014

Viewpoints: Ezekiel Emanuel's choice of an age to die; new enrollment numbers still confusing

Seventy-five. That's how long I want to live: 75 years. This preference drives my daughters crazy. It drives my brothers crazy. My loving friends think I am crazy. They think that I can't mean what I say; that I haven't thought clearly about this, because there is so much in the world to see and do. To convince me of my errors, they enumerate the myriad people I know who are over 75 and doing quite well. They are certain that as I get closer to 75, I will push the desired age back to 80, then 85, maybe even 90. I am sure of my position.

22 Sep 2014

Drugs News and Research

Newborn screening can prevent lifelong disability

Tissue-level model of human airway musculature could pave way for patient-specific asthma treatments

UW-Madison and Morgridge researchers are creating tissue chip technology to screen neural toxins

Alectinib promise for crizotinib-resistant NSCLC

Blocking AEG-1 gene expression halts development of liver cancer by regulating inflammation

KemPharm to initiate clinical trials in Canada for lead product candidate KP201

Cedars-Sinai scientists test ELAD bioartificial liver support system for patients with acute liver failure

Enable Injections named winner of 'Buzz of BIO Investor Forum' contest

New evidence-based guidelines for prevention, treatment of POAF

Promising new approach for combating colorectal cancer

Caltech researcher explores link between variable heart rate, health and fitness

Researchers develop T-MOC device to study complex environment surrounding tumors

Immature blood vessels linked to poor sunitinib response

Amgen seeks FDA approval for leukemia drug blinatumomab

C-Path renews grant to advance more effective drug treatments for TB

Phase IIa clinical trial data of ATL1102 in MS patients published in journal Neurology

MIT engineers find new strategy to combat superbugs

New study sheds light on longstanding question about role of mitochondria in motor neuron diseases

EYLEA Injection gets approval in Japan for treatment of myopic CNV

Viewpoints: Ezekiel Emanuel's choice of an age to die; new enrollment numbers still confusing

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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