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Isis receives $4 million in milestone payment from Achaogen for initiation of plazomicin Phase 3 study

Isis Pharmaceuticals, Inc. announced that it has earned a $4 million milestone payment from Achaogen, Inc. associated with the initiation of a Phase 3 study of plazomicin in patients with serious multi-drug resistant (MDR), gram-negative bacterial infections.

17 Sep 2014

UMass Amherst doctoral student in chemistry receives USP's 2014-15 Global Fellowship Award

University of Massachusetts Amherst doctoral student in chemistry Khaja Muneeruddin is one of three promising young scientists to recently receive the 2014-15 Global Fellowship Award from the United States Pharmacopeial Convention, dual publishers of the official pharmacopeia and National Formulary (NF), the book of directions for identifying compound medicines.

17 Sep 2014

Curie-Cancer, Inventiva launch Epicure project that aims to develop epigenetic targets for cancer

Curie-Cancer, the body responsible for developing Institut Curie’s industry partnership activities, and Inventiva, a drug discovery company that focuses on therapeutic approaches involving transcription factors and epigenetic targets, today announce the launch of the Epicure project, which has just received financial backing from France’s national research agency, the ANR [Agence Nationale pour la Recherche].

17 Sep 2014

NIH awards grant to scientist to link drugs, genes and diseases

The National Institutes of Health wants to make the process of finding new drugs faster and better. The effort will help all 27 of its research institutes and centers. So, the nation's medical research agency awarded Tudor Oprea, MD, PhD, a 2-year $4.9 million grant to develop a tool scientists can use to link information about drugs, diseases and genes.

17 Sep 2014

Adding common epilepsy drug to morphine can result in better pain control, say IU researchers

Adding a common epilepsy drug to a morphine regimen can result in better pain control with fewer side effects. Moreover, the combination can reduce the dosage of the opioid needed to be effective, according to a team of pain researchers at Indiana University.

17 Sep 2014

New report outlines cholesterol-targeted approach to treat people at risk for cardiovascular disease

A recent guideline for using statins to reduce atherosclerotic cardiovascular disease has wavered too far from the simple cholesterol goals that have saved thousands of lives in the past decade, and doesn't adequately treat patients as individuals, experts said today in a national report.

17 Sep 2014

Novel genetic discovery identifies new avenues for prostate cancer treatment

A genetic discovery out of the University of Pittsburgh School of Medicine is leading to a highly accurate test for aggressive prostate cancer and identifies new avenues for treatment.

17 Sep 2014

Warwick researchers discover novel drug target for treating postpartum haemorrhage

Researchers at the University of Warwick have discovered a new target for drugs that could prevent the deaths of thousands of women in the developing world due to heavy blood loss after childbirth.

17 Sep 2014

Study: Marijuana users may attempt to manage negative moods by using drug

Adolescents and young adults who smoke marijuana frequently may attempt to manage negative moods by using the drug, according to a study in September's Journal of Studies on Alcohol and Drugs.

17 Sep 2014

Denovo gains all rights from Lilly to develop, manufacture and commercialize enzastaurin drug

Denovo Biopharma, LLC, today announced that it has acquired enzastaurin, a late-stage oncology drug, from Eli Lilly and Company. Denovo gains all rights to develop, manufacture and commercialize enzastaurin globally, including transfer of all intellectual property and other rights, data, and information.

16 Sep 2014

FDA grants Breakthrough Therapy designation to EYLEA Injection for treatment of diabetic retinopathy

Regeneron Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration has granted EYLEA (aflibercept) Injection Breakthrough Therapy designation for the treatment of diabetic retinopathy in patients with diabetic macular edema (DME).

16 Sep 2014

Researchers uncover new pathways that transport sugar molecules to cells

Sugar is a vital source of energy for both plants and animals alike. Understanding just how sugar makes its way into the cell could lead to the design of better drugs for diabetes patients and an increase in the amount of fruits and vegetables farmers are able to grow.

16 Sep 2014

Web based training effective at reducing sexual assaults on U.S. campuses

Web-based training targeted at college-aged men is an effective tool for reducing the number of sexual assaults on U.S. campuses, according to a researcher in the School of Public Health at Georgia State University.

16 Sep 2014

Collaborative study takes important step toward finding targeted treatments for bladder cancer

The story of cancer care seems so simple: find the mutated gene that causes cancer and turn it off or fix it. But rarely does a single gene cause cancer. More often, many genes are altered together to drive the disease. So the challenge becomes sorting out which altered genes are the most to blame in which cancers.

16 Sep 2014

Patients with particular genetic variation more prone to drug-induced pancreatitis

Doctors have discovered that patients with a particular genetic variation are four times more likely to develop pancreatitis if they are prescribed a widely used group of drugs.

16 Sep 2014

Benefits of blood pressure lowering drugs for low risk patients 'still open to question'

Dr Stephen Martin and colleagues argue that this strategy is failing patients and wasting healthcare resources. They call for a re-examination of the threshold and urge clinicians to be cautious about treating low risk patients with blood pressure lowering drugs.

16 Sep 2014

Cochrane Review rejects safety concerns regarding cheap alternative drug for treating eye disease

Health policies which favour using ranibizumab for treating eye disease in older people over safety concerns for a cheaper alternative should take account of a new Cochrane Review published today.

16 Sep 2014

Gilead to boost price of new hepatitis c drug

Gilead Sciences says its next generation drug to combat hepatitis C, slated to launch next month, will be more expensive than $1,000-a-pill Sovaldi, in part because the new treatment will be shorter and simpler. Gilead also struck a deal with Indian generic drugmakers to sell lower-cost versions of Sovaldi in poor countries.

From Baxter International Inc. 16 Sep 2014

MU researchers make new breakthrough in spinal muscular atrophy drug

According to recent studies, approximately one out of every 40 individuals in the United States is a carrier of the gene responsible for spinal muscular atrophy (SMA), a neurodegenerative disease that causes muscles to weaken over time.

16 Sep 2014

GHIT Fund announces new grants to tackle malaria, chagas disease and dengue

The Global Health Innovative Technology Fund, a new public health partnership that is bringing Japanese know-how and investment to the global fight against infectious diseases, today announced seven grant investments totaling US$15.3 million to speed the development of promising drugs and vaccines to battle three insect-borne diseases-malaria, dengue and Chagas disease.

16 Sep 2014

Drugs News and Research

Isis receives $4 million in milestone payment from Achaogen for initiation of plazomicin Phase 3 study

UMass Amherst doctoral student in chemistry receives USP's 2014-15 Global Fellowship Award

Curie-Cancer, Inventiva launch Epicure project that aims to develop epigenetic targets for cancer

NIH awards grant to scientist to link drugs, genes and diseases

Adding common epilepsy drug to morphine can result in better pain control, say IU researchers

New report outlines cholesterol-targeted approach to treat people at risk for cardiovascular disease

Novel genetic discovery identifies new avenues for prostate cancer treatment

Warwick researchers discover novel drug target for treating postpartum haemorrhage

Study: Marijuana users may attempt to manage negative moods by using drug

Denovo gains all rights from Lilly to develop, manufacture and commercialize enzastaurin drug

FDA grants Breakthrough Therapy designation to EYLEA Injection for treatment of diabetic retinopathy

Researchers uncover new pathways that transport sugar molecules to cells

Web based training effective at reducing sexual assaults on U.S. campuses

Collaborative study takes important step toward finding targeted treatments for bladder cancer

Patients with particular genetic variation more prone to drug-induced pancreatitis

Benefits of blood pressure lowering drugs for low risk patients 'still open to question'

Cochrane Review rejects safety concerns regarding cheap alternative drug for treating eye disease

Gilead to boost price of new hepatitis c drug

MU researchers make new breakthrough in spinal muscular atrophy drug

GHIT Fund announces new grants to tackle malaria, chagas disease and dengue

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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