Malignant News and Research

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NUS researchers discover promising treatment for anaplastic thyroid carcinoma

Anaplastic thyroid carcinoma is an aggressive type of cancer with a poor prognosis for which there is currently no effective treatment. Researchers from the National University of Singapore have discovered for the first time that an epithelial basement membrane protein, called laminin-5 gamma-2 (LAMC2), has the potential to be an ideal target for the treatment of ATC.

18 Feb 2014

Researchers use new technique that can partially move tumors from inoperable locations in brain

One factor that makes glioblastoma cancers so difficult to treat is that malignant cells from the tumors spread throughout the brain by following nerve fibers and blood vessels to invade new locations.

17 Feb 2014

Improper handling of intravenous saline leads to rare bacteria outbreak

Improper handling of intravenous saline at a West Virginia outpatient oncology clinic was linked with the first reported outbreak of Tsukamurella spp., gram-positive bacteria that rarely cause disease in humans, in a new report from the Centers for Disease Control and Prevention (CDC). The report was published in the March issue of Infection Control and Hospital Epidemiology, the journal of the Society for Healthcare Epidemiology of America.

14 Feb 2014

New approach for treating leukemia

A group of researchers at the Institute for Research in Immunology and Cancer (IRIC) of Université de Montréal discovered a promising new approach to treating leukemia by disarming a gene that is responsible for tumor progression.

14 Feb 2014

Researchers discover promising new approach for leukemia treatment

A group of researchers at the Institute for Research in Immunology and Cancer of Universit- de Montr-al discovered a promising new approach to treating leukemia by disarming a gene that is responsible for tumor progression. That gene, known as Brg1 is a key regulator of leukemia stem cells that are the root cause of the disease, resistance to treatment and relapse.

13 Feb 2014

Researchers discover highly accurate, noninvasive test to identify benign pancreatic cysts

Researchers at the Indiana University School of Medicine have discovered a highly accurate, noninvasive test to identify benign pancreatic cysts, which could spare patients years of nerve-racking trips to the doctor or potentially dangerous surgery.

12 Feb 2014

Researchers discover that bladder cancer shares genetic similarities with two forms of breast cancer

Researchers at the UNC School of Medicine conducted a comprehensive genetic analysis of invasive bladder cancer tumors to discover that the disease shares genetic similarities with two forms of breast cancer.

12 Feb 2014

Combination of SYK and FLT3 enzymes promotes progression of acute myelogenous leukemia

Reinforcing the need to look beyond genomic alterations to understand the complexity of cancer, researchers from Dana-Farber/Boston Children's Cancer and Blood Disorders Center report that a normal enzyme called SYK pairs with FLT3, the most commonly mutated enzyme found in acute myelogenous leukemia (AML), to promote progression of the disease.

11 Feb 2014

Children who received radiation as part of treatment may have lower long-term survival rates, says study

The first comprehensive, large-scale cohort study of the long-term survival of children treated for low-grade gliomas, the most common pediatric brain tumor, finds that almost 90 percent are alive 20 years later and that few die from the tumor as adults.

4 Feb 2014

IDH1 gene mutation determines best treatment for malignant astrocytomas

Astrocytomas are the most common malignant brain tumors. While most patients' tumors prove to be quite aggressive, outcomes overall can vary widely, with some patients surviving for many years.

4 Feb 2014

RNAi-based screening offers MPM treatment hope

Research using RNA interference-based screening has identified several potential targets for the treatment of malignant pleural mesothelioma.

31 Jan 2014

Heart transplantation continues to be "gold standard" treatment for end-stage heart failure

Heart transplantation continues to be the "gold standard" treatment for end-stage heart failure, and a large number of patients now live 20 years or more after surgery, according to a study in the February 2014 issue of The Annals of Thoracic Surgery.

30 Jan 2014

Spontaneous tumorigenic transformation of human MSCs can occur during cell culture expansion

Researchers at Erasmus University Medical Center Rotterdam, The Netherlands, led by Dr. Qiuwei Pan and Dr. Luc van der Laan, have discovered that spontaneous tumorigenic transformation of human mesenchymal stem/stromal cells (MSCs) can occur during cell culture expansion, although the frequency is relatively low and often only observed after extensive passage in culture.

30 Jan 2014

Findings on molecular defects behind bladder cancer may pave way for new, targeted treatments

The once sketchy landscape of the molecular defects behind bladder cancer now resembles a road map to new, targeted treatments thanks to the unified efforts of scientists and physicians at 40 institutions.

30 Jan 2014

Research shows promise for developing a method of clearly identifying cancerous tissue during surgery

First-of-its-kind research by the Innovation Institute at Henry Ford Hospital shows promise for developing a method of clearly identifying cancerous tissue during surgery on one of the most common and deadliest types of brain tumor.

30 Jan 2014

UNC researchers develop new radiation-free ultrasound technique to detect, monitor cancer

While ultrasound provides a less expensive and radiation-free alternative to detecting and monitoring cancer compared to technologies such as X-rays, CT scans, and MRIs, ultrasound has seen limited use in cancer treatment due to clarity and resolution issues.

29 Jan 2014

Veterans with exposure to Agent Orange may be at higher risk for skin cancer

Vietnam War veterans with prior exposure to the herbicide Agent Orange may be at higher risk for certain types of skin cancer, suggests a report in the February issue of Plastic and Reconstructive Surgery-, the official medical journal of the American Society of Plastic Surgeons (ASPS).

29 Jan 2014

Researchers identify therapeutic target for cervix cancer

Gene related to the proliferation of cancerous cells blocked through molecular technology. A group of researchers from Mexico's General Hospital, Health Secretariat, Medicine Faculty and the Institute of Cellular Physiology of the National Autonomous University of Mexico (UNAM) identified a therapeutic target for cervix cancer: gene CDKN3.

28 Jan 2014

Specific compounds found in exhaled breath may help diagnose lung cancer in early stages

Specific compounds found in exhaled breath may help diagnose lung cancer in its early stages, according to a study released today at the 50th Annual Meeting of The Society of Thoracic Surgeons.

28 Jan 2014

BioTime: OncoCyte initiates clinical development of bladder cancer diagnostic test in U.S, China

BioTime, Inc. and its subsidiary OncoCyte Corporation today announced that OncoCyte has initiated clinical development of its bladder cancer diagnostic test in both the United States and China.

28 Jan 2014

Malignant News and Research

NUS researchers discover promising treatment for anaplastic thyroid carcinoma

Researchers use new technique that can partially move tumors from inoperable locations in brain

Improper handling of intravenous saline leads to rare bacteria outbreak

New approach for treating leukemia

Researchers discover promising new approach for leukemia treatment

Researchers discover highly accurate, noninvasive test to identify benign pancreatic cysts

Researchers discover that bladder cancer shares genetic similarities with two forms of breast cancer

Combination of SYK and FLT3 enzymes promotes progression of acute myelogenous leukemia

Children who received radiation as part of treatment may have lower long-term survival rates, says study

IDH1 gene mutation determines best treatment for malignant astrocytomas

RNAi-based screening offers MPM treatment hope

Heart transplantation continues to be "gold standard" treatment for end-stage heart failure

Spontaneous tumorigenic transformation of human MSCs can occur during cell culture expansion

Findings on molecular defects behind bladder cancer may pave way for new, targeted treatments

Research shows promise for developing a method of clearly identifying cancerous tissue during surgery

UNC researchers develop new radiation-free ultrasound technique to detect, monitor cancer

Veterans with exposure to Agent Orange may be at higher risk for skin cancer

Researchers identify therapeutic target for cervix cancer

Specific compounds found in exhaled breath may help diagnose lung cancer in early stages

BioTime: OncoCyte initiates clinical development of bladder cancer diagnostic test in U.S, China

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