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Lung cancer cells activate different signaling pathways in response to KRAS inhibitors

Genetic alterations of the KRAS gene are some of the most common mutations in lung cancer patients, but unfortunately these patients have few effective treatment options.

1 Mar 2021

A new hub established for development of oligonucleotide drugs

In recent years, techniques have been developed to treat diseases with what are known as oligonucleotide drugs, based on short DNA or RNA molecules.

1 Mar 2021

Study: Highly efficient and balanced immune response key to avoiding COVID-19 symptoms

By analyzing blood samples from individuals infected with SARS-CoV-2, researchers in Singapore have begun to unpack the different responses by the body's T cells that determine whether or not an individual develops COVID-19.

1 Mar 2021

Toxicological assessment of hemp-containing foods

In order to avoid the occurrence of such effects, the Federal Institute for Health Protection of Consumers and Veterinary Medicine (BgVV) recommended guidance values for maximum THC levels in various food groups in 2000.

1 Mar 2021

Study could offer a new way to treat Type 1 and Type 2 diabetes

Blocking cell receptors for glucagon, the counter-hormone to insulin, cured mouse models of diabetes by converting glucagon-producing cells into insulin producers instead, a team led by UT Southwestern reports in a new study.

1 Mar 2021

New technique uncovers the tricks used by cancer cells to evade immunotherapies

By harnessing the immune system against cancer, immunotherapies have revolutionized the way some types of cancer are treated. But most patients--across cancer types--do not respond, and in most cases, scientists are at a loss as to why.

1 Mar 2021

A region within GLI1 gene could potentially be targeted as cancer treatment

Scientists from the Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago found that a region within the DNA of the cancer-promoting GLI1 gene is directly responsible for regulating this gene's expression.

1 Mar 2021

Traumatic childhood and combat experiences associated with veterans' suicidal thoughts

The rate of suicide among post-9/11 military veterans has been rising for nearly a decade. While there are a number of factors associated with suicide, veterans have unique experiences that may contribute to them thinking about killing themselves.

1 Mar 2021

Researchers develop mutant gene-targeted immunotherapy approach to fight cancers

A novel targeted immunotherapy approach developed by researchers at the Ludwig Center, the Lustgarten Laboratory, and Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center employs new antibodies against genetically altered proteins to target cancers.

1 Mar 2021

Exposure to periods of low oxygen can result in underdeveloped jaw cartilage

Breathing in adequate amounts of oxygen is critical for human life. However, certain disorders can cause individuals to go through periods where they are exposed to periodical low levels of oxygen, called intermittent hypoxia (IH).

1 Mar 2021

New type of ultrasound scan could improve outcome from brain tumor surgery

A type of ultrasound scan can detect cancer tissue left behind after a brain tumor is removed more sensitively than surgeons, and could improve the outcome from operations, a new study suggests.

1 Mar 2021

Study discovers similarities between the genetic bases of various eating disorders

Anorexia nervosa, bulimia nervosa and binge-eating disorder are the three main eating disorders that 4 out of in 10 individuals living in Western Europe will experience at some point in their lives.

1 Mar 2021

ACGT awards $500,000 to advance immunotherapy approach for treating solid tumors

A scientific team led by Brian Brown, PhD, Professor of Genetics and Genomic Sciences and Associate Director of the Precision Immunology Institute at the Icahn School of Medicine at Mount Sinai (New York, New York), has been awarded $500,000 from Alliance for Cancer Gene Therapy to advance a promising immunotherapy approach to fight lung cancer and other solid tumor cancers.

1 Mar 2021

Early tracheostomy could reduce recovery time in critical COVID-19, say researchers

A new study by researchers at the Northwestern University Feinberg School of Medicine, USA, reports the findings of a study on the safety of tracheostomy of critically ill patients and the feasibility of decannulation in most survivors. The researchers view this as a means to improve care in these patients

1 Mar 2021

New paper discusses how smoking may affect risk for COVID-19

A new paper published online in the Annals of the American Thoracic Society discusses how smoking may affect risk for COVID-19 and the types of research that are needed to better understand the link between smoking and COVID-19 risk.

1 Mar 2021

In-person rapid mortality review process sparked improvements in patient care

An in-person multidisciplinary rapid mortality review (RMR) process helped identify specific areas to improve patient care at a Los Angeles hospital, according to a study published in American Journal of Critical Care.

1 Mar 2021

Black churches fill a unique role in combating vaccine fears

In the hospital with covid-19 in December, Lavina Wafer tired of the tubes in her nose and wondered impatiently why she couldn't be discharged. A phone call with her pastor helped her understand that the tube was piping in lifesaving oxygen, which had to be slowly tapered to protect her.

1 Mar 2021

Connecticut is doling out vaccines based strictly on age. It’s simpler, but is it fair?

With Covid vaccines expected to remain scarce into early spring, Connecticut has scrapped its complicated plans to prioritize immunizations for people under 65 with certain chronic conditions and front-line workers. Instead, the state will primarily base eligibility on age.

1 Mar 2021

‘Into the Covid ICU’: A new doctor bears witness to the isolation, inequities of pandemic

This week marks a grim milestone: Half a million Americans have died of Covid-19. KHN reporter Jenny Gold, in collaboration with Reveal from the Center for Investigative Reporting and PRX, spent eight months following one first-year medical resident working on the front lines of the pandemic.

1 Mar 2021

Study: Eating the right '5-a-day' mix of fruits and vegetables is likely optimal amount for longer life

Studies representing nearly 2 million adults worldwide show that eating about five daily servings of fruits and vegetables, in which 2 are fruits and 3 are vegetables, is likely the optimal amount for longer life, according to new research published today in the American Heart Association's flagship journal Circulation.

1 Mar 2021

Medicine News and Research

Lung cancer cells activate different signaling pathways in response to KRAS inhibitors

A new hub established for development of oligonucleotide drugs

Study: Highly efficient and balanced immune response key to avoiding COVID-19 symptoms

Toxicological assessment of hemp-containing foods

Study could offer a new way to treat Type 1 and Type 2 diabetes

New technique uncovers the tricks used by cancer cells to evade immunotherapies

A region within GLI1 gene could potentially be targeted as cancer treatment

Traumatic childhood and combat experiences associated with veterans' suicidal thoughts

Researchers develop mutant gene-targeted immunotherapy approach to fight cancers

Exposure to periods of low oxygen can result in underdeveloped jaw cartilage

New type of ultrasound scan could improve outcome from brain tumor surgery

Study discovers similarities between the genetic bases of various eating disorders

ACGT awards $500,000 to advance immunotherapy approach for treating solid tumors

Early tracheostomy could reduce recovery time in critical COVID-19, say researchers

New paper discusses how smoking may affect risk for COVID-19

In-person rapid mortality review process sparked improvements in patient care

Black churches fill a unique role in combating vaccine fears

Connecticut is doling out vaccines based strictly on age. It’s simpler, but is it fair?

‘Into the Covid ICU’: A new doctor bears witness to the isolation, inequities of pandemic

Study: Eating the right '5-a-day' mix of fruits and vegetables is likely optimal amount for longer life

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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