Cancer Prevention News and Research

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Celebrex provides a two pronged attack against prostate cancer

Celecoxib, a selective COX-2 inhibitor with promising anti-cancer properties, has now been found to attack prostate cancer cells in a second way that differs from Vioxx (rofecoxib), another anti-inflammatory drug that also inhibits COX-2.

1 Mar 2005

Common epigenetic problem doubles cancer risk

In experiments with mice, a team of scientists from the United States, Sweden and Japan has discovered that having a double dose of one protein is sufficient to change the normal balance of cells within the lining of the colon, thereby doubling the risk that a cancer-causing genetic mutation will trigger a tumor there.

27 Feb 2005

Is it exercise or dieting that helps prevent cancer?

Scientists and health professionals have long believed that maintaining a healthy - or "ideal" - weight makes a difference in decreasing an individual's risk for cancer. But one lingering question is whether or not it's better, in terms of cancer prevention, if that weight is reached and maintained by dieting or by exercising.

23 Feb 2005

Vioxx doubles risk of heart attacks and strokes

The largest prospective trial ever examining the anti-inflammatory drug Vioxx as a chemoprevention agent found that the risk of developing a cardiovascular "event" - heart attacks and/or strokes - was almost double in patients who received the drug, compared to patients who took the placebo, according to a study out Feb. 15 on-line in The New England Journal of Medicine.

15 Feb 2005

Cancer pledge needs anti-smoking action

The community will question the Labor Government's commitment to boost spending on cancer prevention while it does little to stop passive smoking killing more and more West Australians, the AMA (WA) said today.

8 Feb 2005

Why some men develop aggressive prostate cancer that becomes resistant to hormone-withdrawal therapy

Researchers found that certain mutations in a protein called the androgen receptor cause advanced and invasive prostate cancer when put into otherwise healthy mice. The androgen receptor's normal function is to control growth of the prostate gland in response to cues from male hormones called androgens, which have long been thought to stimulate prostate tumors.

26 Jan 2005

Tobacco smoke triggers the production of COX-2

Tobacco smoke triggers the production of COX-2, a cellular protein linked to the development and progression of cancer, according to research published in the January 15 issue of the journal Cancer Research.

16 Jan 2005

Study links meat consumption to colon cancer

A major American Cancer Society study finds people who reported the highest consumption of red and processed meat had a significantly higher risk of colorectal cancer than those who reported the least consumption.

12 Jan 2005

Elevated glucose levels and diabetes associated with a greater risk for cancer

New research involving more than one million people indicates that having high fasting serum glucose levels and diabetes are risk factors for several major cancers, according to a study in the January 12 issue of JAMA.

12 Jan 2005

High consumption of red meat increases risk for colorectal cancer

High consumption of red and processed meat over a long period of time is associated with an increased risk for a certain type of colon cancer, according to a study in the January 12 issue of JAMA.

12 Jan 2005

Trial of naproxen and celecoxib suspended

Use of study drugs in a large, federally funded Alzheimer prevention trial has been suspended following a decision by the study's leadership on Dec. 17, 2004.

9 Jan 2005

Abraxane, first in a new class of albumin-bound nanotechnology for the treatment of metastatic breast cancer

Abraxane (paclitaxel protein-bound particles for injectable suspension), a next generation taxane, and the first in a new class of albumin-bound nanotechnology, was approved for the treatment of metastatic breast cancer.

9 Jan 2005

Direct modulation of progesterone signaling appears to influence ovarian cancer risk

A woman's risk of ovarian cancer rises significantly if she carries either of two previously unexamined variations in the gene that codes for the progesterone receptor, according to a team of researchers led by scientists from the Keck School of Medicine of the University of Southern California.

5 Jan 2005

Study investigates value of "Center of Excellence" designation

A new study says cancer surgery performed at a medical center designated by the National Cancer Institute (NCI) as a "center of excellence" is associated with less risk of death soon after surgery than if performed at a high-volume surgery center, but finds no difference in five-year survival rates.

27 Dec 2004

Vitamin E supplements may reduce the risk for death from amyotrophic lateral sclerosis (ALS)

Researchers from the Harvard School of Public Health and the American Cancer Society have found that regular use of vitamin E supplements may reduce the risk for death from amyotrophic lateral sclerosis (ALS) also known as Lou Gehrig’s Disease.

21 Dec 2004

PAHO - Cervical cancer kills almost a quarter-million women worldwide each year

The Pan American Health Organization (A regional office of the World Health Organization), as a member of the Alliance for Cervical Cancer Prevention (ACCP), has issued a new publication and reported that cervical cancer—while largely preventable—kills almost a quarter-million women worldwide each year.

20 Dec 2004

Many women at high risk for breast cancer are foregoing tamoxifen

Many women at high risk for breast cancer are foregoing tamoxifen, the first FDA-approved drug for prevention of breast cancer, due to concerns about side effects, increased risk of other cancers, and lack of information, a new study by researchers in Boston shows. The study was published in the December 14 in the Journal of Clinical Oncology.

20 Dec 2004

Celebrex suspension

The National Institutes of Health (NIH) announced that it has suspended the use of COX-2 inhibitor celecoxib (Celebrex™ Pfizer, Inc.) for all participants in a large colorectal cancer prevention clinical trial conducted by the National Cancer Institute (NCI).

19 Dec 2004

Genealogy in a cancer prevention curriculum for high school students

A team of researchers from Virginia Commonwealth University are using an old tool to teach new information about cancer: the family tree.

19 Dec 2004

Vegetables such as cabbage, broccoli, sprouts or cauliflower could help in the fight against cancer

Researchers from the Wales College Of Medicine, Cardiff University in the UK have discovered what may be a clue to the prevention and treatment of cancer. They have found that when vegetables such as cabbage, broccoli, sprouts or cauliflower are eaten, they could help in the fight against cancer.

16 Nov 2004