Infectious Diseases News and Research

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Researchers reveal unique signature of genes expressed by hematopoietic stem cells

Hematopoietic stem cells (HSCs) have the capacity to both self-renew and differentiate into all mature blood cell types, making them promising treatments for a variety of diseases.

2 Mar 2022

Targeting necroptosis using a necroptosis inhibitor lessens myositis-induced muscle weakness

A new study has suggested that treatment to target necroptosis in muscle fibers using a necroptosis inhibitor lessens myositis-induced muscle weakness as well as muscle cell death and inflammation in the muscles. This has been shown to be a promising strategy for treating polymyositis.

2 Mar 2022

Study finds booster shot did produce effective levels of neutralizing antibodies against omicron

A new study using serum from human blood samples suggests neutralizing antibody levels produced by two-dose mRNA vaccines against the original and early variants of the SARS-CoV-2 virus wane substantially over time, and offer essentially no protection against the omicron variant.

2 Mar 2022

People in England limited contact with others even outside of lockdown periods, suggests study

Transmission of respiratory viruses depends partly on the rate of close social contacts in a population. A study publishing March 1st in PLOS Medicine by Amy Gimma at the London School of Hygiene and Tropical Medicine, United Kingdom, and colleagues suggests that during the most restrictive period of lockdown in the United Kingdom, the number of reported contacts decreased by 75% from pre-pandemic levels.

2 Mar 2022

Phase 2/3 study of oral RHB-107 in non-hospitalized COVID-19 patients shows promising results

RedHill Biopharma Ltd., a specialty biopharmaceutical company, today announced positive top-line results from the Phase 2 part of the Phase 2/3 study of once-daily oral RHB-107 (upamostat) in non-hospitalized symptomatic COVID-19 patients, predominantly conducted in the U.S. (60/61 patients) as well as South Africa.

1 Mar 2022

Face masks can play a crucial role in reducing the spread of Covid infection

An international research team from universities including Chalmers University of Technology, Sweden, the University of Padua and the University of Udine in Italy, and the University of Vienna, Austria, has developed a new theoretical model to better assess the risks of spreading viruses such as Covid-19 - with and without a face mask.

1 Mar 2022

Using AI to detect antibiotic resistance

In this interview, we speak to Professor Karsten Borgwardt and Professor Adrian Egli about their latest research that used AI to predict antibiotic resistance.

1 Mar 2022

Effectiveness of Pfizer-BioNTech, Moderna, and Oxford-AstraZeneca COVID-19 vaccines in preventing severe SARS-CoV-2 infection

A new study compared the effectiveness of the Pfizer-BioNTech, Moderna, and Oxford-AstraZeneca COVID-19 vaccines in preventing SARS-CoV-2 infections.

1 Mar 2022

J&J-vaxxed, mRNA-boosted, and pondering a third shot

Yes, we are all exhausted by the covid pandemic. Flummoxed by the constantly shifting science and guidelines. Worried about a succession of scary new variants, each with its own name, like hurricanes.

1 Mar 2022

Study identifies olfactory dysfunction as an early symptom of COVID-19

In a new study, scientists researched olfactory loss and dysfunction among COVID-19 patients to objectively characterize it as a symptom of COVID-19.

1 Mar 2022

New signature initiative on increasing alcohol taxes could benefit people’s health, reduce mortality

Across the Region, alcohol consumption leads to almost one million deaths each year from a wide range of causes, including cardiovascular diseases, cancers and other noncommunicable diseases (NCDs), as well as infectious diseases and injuries.

28 Feb 2022

Antibody prevalence found to be highest among secondary school students in England

Over three quarters of secondary school pupils and nearly half of primary schools pupils are estimated to have had antibodies against COVID-19 in December last year, according to new data from the Schools Infection Survey (SIS).

28 Feb 2022

Triple antibody cocktail is a promising candidate for immunotherapy against SARS-CoV-2 variants of concern

Researchers generated a panel of bnAbs against SARS-CoV, SARS-CoV-2, and its variant VOCs, including Omicron from sequentially immunized mice.

28 Feb 2022

Study finds Omicron sublineage BA.2 is less pathogenic in rodent models than prior SARS-CoV-2 variants

Researchers evaluated the pathogenicity and replication potential of SARS-CoV-2 VOC Omicron lineage, BA.2 in immunocompetent mice and hamsters.

28 Feb 2022

Noncovalent protease inhibitors against SARS-CoV-2 and other coronaviruses

In a new study published in ACS Infectious Diseases journal, scientists biochemically and structurally evaluated the PLpro from a subgroup 2b bat coronavirus, BtSCoV-Rf1.2004, to identify unique structural features or enzymatic biases of the subgroup 2b.

28 Feb 2022

LJI researchers discover new genes in CD4+ "helper" T cell subsets

T cells play important roles in helping to fight infections and cancers - and they can also drive autoimmune diseases. Now researchers at La Jolla Institute for Immunology (LJI) have discovered new genes in CD4+ "helper" T cell subset that are linked to risk of autoimmune diseases.

25 Feb 2022

Dr. Dennis Ownby wins AAAAI's 2022 Distinguished Clinician Recognition Award

Dr. Dennis Ownby, former chief of the Section of Allergy, Immunology and Rheumatology at the Medical College of Georgia, is the recipient of the American Academy of Allergy, Asthma and Immunology's 2022 Distinguished Clinician Recognition Award.

25 Feb 2022

Research could pave the way for adoption of precision medicine approaches for COVID-19

The COVID-19 pandemic has revealed a frightening reality; the course of infection with this disease is highly variable. Some young patients have died from the virus, whereas several elderly people have survived without experiencing respiratory symptoms at all. Researchers are left wondering: why?

25 Feb 2022

A regional corner of Africa found to be a hotspot for highly infectious diseases

A regional corner of Africa is a hotspot for cases of HIV, tuberculosis and malaria, prompting researchers to call for targeted health support rather than a national response.

25 Feb 2022

Rarely-used antibiotic could be a safe and affordable treatment for neonatal sepsis

An antibiotic rarely used in infants admitted to hospitals could be a safe and affordable, life-saving treatment for neonatal sepsis, in the face of growing resistance to other drugs, a study finds.

24 Feb 2022

Infectious Diseases News and Research

Researchers reveal unique signature of genes expressed by hematopoietic stem cells

Targeting necroptosis using a necroptosis inhibitor lessens myositis-induced muscle weakness

Study finds booster shot did produce effective levels of neutralizing antibodies against omicron

People in England limited contact with others even outside of lockdown periods, suggests study

Phase 2/3 study of oral RHB-107 in non-hospitalized COVID-19 patients shows promising results

Face masks can play a crucial role in reducing the spread of Covid infection

Using AI to detect antibiotic resistance

Effectiveness of Pfizer-BioNTech, Moderna, and Oxford-AstraZeneca COVID-19 vaccines in preventing severe SARS-CoV-2 infection

J&J-vaxxed, mRNA-boosted, and pondering a third shot

Study identifies olfactory dysfunction as an early symptom of COVID-19

New signature initiative on increasing alcohol taxes could benefit people’s health, reduce mortality

Antibody prevalence found to be highest among secondary school students in England

Triple antibody cocktail is a promising candidate for immunotherapy against SARS-CoV-2 variants of concern

Study finds Omicron sublineage BA.2 is less pathogenic in rodent models than prior SARS-CoV-2 variants

Noncovalent protease inhibitors against SARS-CoV-2 and other coronaviruses

LJI researchers discover new genes in CD4+ "helper" T cell subsets

Dr. Dennis Ownby wins AAAAI's 2022 Distinguished Clinician Recognition Award

Research could pave the way for adoption of precision medicine approaches for COVID-19

A regional corner of Africa found to be a hotspot for highly infectious diseases

Rarely-used antibiotic could be a safe and affordable treatment for neonatal sepsis

NGS for Infectious Disease Surveillance eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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