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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

New drug target may prevent consequences of ACL tear in athletes

Striking the likes of Chicago Bulls' Derrick Rose, L.A. Lakers' Kobe Bryant and Detroit Tigers' Victor Martinez, tears in the anterior cruciate ligament (ACL) are one of the most rampant and serious knee injuries among athletes.

14 Jun 2013

CSHL scientists solve the mystery of why some infants born with grave syndrome

By identifying a protein that acts as a genetic modifier, scientists at Cold Spring Harbor Laboratory have solved the mystery of why some infants are born with a grave syndrome consisting of cleft palate and major deformities of the skin and limbs, while other infants bearing the same predisposing genetic mutation bear little or no sign of the illness, called EEC.

14 Jun 2013

Pew Charitable Trusts selects NYU professor as Pew Scholar in Biomedical Sciences

Fei Li, an assistant professor in New York University's Department of Biology, has been selected as a Pew Scholar in the Biomedical Sciences by The Pew Charitable Trusts.

14 Jun 2013

Study provides new insight into how pyrazinamide works

Pyrazinamide (PZA)-a frontline tuberculosis drug-kills dormant persister bacteria and plays a critical role in shortening TB therapy. PZA is used for treating both drug susceptible and multi-drug resistant TB but resistance to PZA occurs frequently and can compromise treatment.

14 Jun 2013

Penn Medicine researchers identify key molecular player in recurrent breast cancer

According to the American Cancer Society, nearly 40,000 women in the United States will succumb to breast cancer this year. Most of these women will die not from the primary tumor but rather tumor recurrence - the reappearance of the disease following treatment.

14 Jun 2013

Depression, antidepressant use may increase risk for diabetes and CVD in postmenopausal women

Postmenopausal women who use antidepressant medication or suffer from depression might be more likely to have a higher body mass index, larger waist circumference and inflammation-all associated with increased risk for diabetes and cardiovascular disease, according to a study led by University of Massachusetts Medical School investigator Yunsheng Ma, PhD, MD, MPH, and published in the June 13 issue of the American Journal of Public Health.

14 Jun 2013

Nervous system and nerve-growth factor play major role in arthritis

Arthritis is a debilitating disorder affecting one in 10 Canadians, with pain caused by inflammation and damage to joints.

14 Jun 2013

Xgeva receives FDA approval for treating giant cell tumor of the bone

The U.S. Food and Drug Administration today expanded the approved use of Xgeva (denosumab) to treat adults and some adolescents with giant cell tumor of the bone, a rare and usually non-cancerous tumor.

14 Jun 2013

Perfinity, Thermo Fisher Scientific sign co-marketing agreement for automated online biopharmaceutical analysis system

Perfinity Biosciences Inc. has announced the signing of an agreement with Thermo Fisher Scientific Inc., the world leader in serving science, to co-market an automated protein sample preparation and analysis system.

From Thermo Fisher Scientific Inc. 13 Jun 2013

PRISM Pharma announces closing of $15 million Series C financing

PRISM Pharma Co., Ltd., a drug discovery company focused on developing small molecule technologies that modulate protein-protein interactions, today announced the close of an approximately $15 million (approximately ¥1.4 billion) Series C financing.

13 Jun 2013

New data on PROLOR Biotech's hGH-CTP and MOD-6030 to be presented at ENDO 2013

PROLOR Biotech, Inc., today announced that the company will present new data on its long-acting human growth hormone (hGH-CTP) in Phase III development for the treatment of growth hormone deficiency and its long acting oxyntomodulin (MOD-6030) in preclinical development for the treatment of obesity and type 2 diabetes at ENDO 2013, the 95th Annual Meeting of the Endocrine Society.

13 Jun 2013

Omeros gets regulatory clearance to begin Phase 1 clinical trial of OMS721

Omeros Corporation today announced that it has obtained regulatory clearance to start the Phase 1 clinical trial evaluating OMS721, the Company's lead human monoclonal antibody from its mannan-binding lectin-associated serine protease-2 (MASP-2) program.

13 Jun 2013

Scientists measure major difference between brains of patients with Alzheimer's disease and healthy family members

Scientists at Washington University School of Medicine in St. Louis have measured a significant and potentially pivotal difference between the brains of patients with an inherited form of Alzheimer's disease and healthy family members who do not carry a mutation for the disease.

13 Jun 2013

Pregnancy carried to childbirth increases risk of ACPA-negative RA

Epidemiological data presented today at EULAR 2013, the Annual Congress of the European League Against Rheumatism, demonstrate that pregnancy carried to childbirth (parity) increases the risk of ACPA-negative rheumatoid arthritis.

13 Jun 2013

Study: Depression indicators are stronger predictors of work disability in early arthritis

Data presented today at EULAR 2013, the Annual Congress of the European League Against Rheumatism, demonstrate that indicators of depression are stronger predictors of work disability in early arthritis than disease activity or response to therapy.

13 Jun 2013

Slowdowns in transport of important molecules may contribute to development of ALS

Slowdowns in the transport and delivery of nutrients, proteins and signaling molecules within nerve cells may contribute to the development of the neurodegenerative disorder ALS, according to researchers at the University of Illinois at Chicago College of Medicine.

13 Jun 2013

Effective method to restore sight to patients with blinding diseases

Researchers at the University of California, Berkeley, have developed an easier and more effective method for inserting genes into eye cells that could greatly expand gene therapy to help restore sight to patients with blinding diseases ranging from inherited defects like retinitis pigmentosa to degenerative illnesses of old age, such as macular degeneration

13 Jun 2013

Common medications reduce brain plaques in mice

Multiple drug classes commonly prescribed for common medical conditions are capable of influencing the onset and progression of Alzheimer's disease, according to researchers at The Mount Sinai Medical Center. The findings are published online in the journal PLoS One.

13 Jun 2013

New study shows treatment with brodalumab demonstrates clinical response in subjects with PsA

A new study presented today at EULAR 2013, the Annual Congress of the European League Against Rheumatism, shows that treatment with brodalumab demonstrates significant clinical response and an acceptable safety profile in subjects with psoriatic arthritis.

13 Jun 2013

SAP and TUM decode human proteome and provide data for biomedical research

As personalized medicine is on the rise, the healthcare field is discovering the opportunities of "big data" analysis. The result of a joint project between the TUM Chair of Proteomics and Bioanalytics, SAP and the SAP Innovation Center, ProteomicsDB, is a major step forward in human proteomics.

12 Jun 2013

Protein News and Research

Further Reading

New drug target may prevent consequences of ACL tear in athletes

CSHL scientists solve the mystery of why some infants born with grave syndrome

Pew Charitable Trusts selects NYU professor as Pew Scholar in Biomedical Sciences

Study provides new insight into how pyrazinamide works

Penn Medicine researchers identify key molecular player in recurrent breast cancer

Depression, antidepressant use may increase risk for diabetes and CVD in postmenopausal women

Nervous system and nerve-growth factor play major role in arthritis

Xgeva receives FDA approval for treating giant cell tumor of the bone

Perfinity, Thermo Fisher Scientific sign co-marketing agreement for automated online biopharmaceutical analysis system

PRISM Pharma announces closing of $15 million Series C financing

New data on PROLOR Biotech's hGH-CTP and MOD-6030 to be presented at ENDO 2013

Omeros gets regulatory clearance to begin Phase 1 clinical trial of OMS721

Scientists measure major difference between brains of patients with Alzheimer's disease and healthy family members

Pregnancy carried to childbirth increases risk of ACPA-negative RA

Study: Depression indicators are stronger predictors of work disability in early arthritis

Slowdowns in transport of important molecules may contribute to development of ALS

Effective method to restore sight to patients with blinding diseases

Common medications reduce brain plaques in mice

New study shows treatment with brodalumab demonstrates clinical response in subjects with PsA

SAP and TUM decode human proteome and provide data for biomedical research

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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