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Nivolumab drug highly effective for Hodgkin's lymphoma

A phase I clinical trial of nivolumab found that the immune-boosting drug is a highly effective therapy for Hodgkin's lymphoma. The multi-institution study, led by Mayo Clinic, indicated that the drug was safe and led to an 87 percent response rate in patients who had failed on other treatments.

7 Dec 2014

Study shows link between cardiac abnormalities, sudden unexpected death in epilepsy

Groundbreaking findings describing the link between cardiac abnormalities and sudden unexpected death in epilepsy (SUDEP) will be presented at the American Epilepsy Society's Annual Meeting in December.

7 Dec 2014

New study explores reliability of optogenetics as method of intervention of temporal lobe seizures

Optogenetics is one of the hottest tools in biomedical research today, a method that uses gene therapy to deliver light-sensitive proteins into specific cells. This new tool allows researchers to interact with a single cell or a network of cells with exquisite precision. Whereas imaging and other technologies allow researchers to watch the brain in action, optogenetics enables them to influence those actions.

7 Dec 2014

Study provides insights into genetic underpinnings of childhood epilepsies

Technological advances in genetic analysis have uncovered changes in single genes that account for a surprising number of infantile and early-childhood epilepsies. Though some of the affected genes have been identified, the physical manifestations of these alterations remain largely uncharacterized.

7 Dec 2014

New treatment combinations improve outcomes for vulnerable patient with hard-to-treat disease

New treatment combinations and targeted therapies for lymphoma and multiple myeloma are improving outcomes for vulnerable patient populations with hard-to-treat disease, according to studies presented today at the 56th American Society of Hematology Annual Meeting and Exposition.

7 Dec 2014

Scientists devise powerful algorithm to improve effectiveness of research technology harnessing RNAi

Scientists at Cold Spring Harbor Laboratory have devised a powerful algorithm that improves the effectiveness of an important research technology harnessing RNA interference, or RNAi.

7 Dec 2014

Study: Key protein may help prevent tumor growth, promote wound healing

A key protein may represent a new way to use the immune system to speed healing and counter inflammatory, infectious and autoimmune diseases, according to study led by researchers at the Icahn School of Medicine at Mount Sinai and published in the December issue of Cell Reports.

7 Dec 2014

Pediatric concussions increase significantly between 2003 and 2010 in Ontario

The number of children and youth treated for concussions in both emergency departments and physician's offices in Ontario increased significantly between 2003 and 2010, with falls, hockey and skating injuries identified as the leading causes of pediatric concussion, according to a new joint study out of York University and the Institute for Clinical Evaluative Sciences.

7 Dec 2014

BUSM's Carmela Abraham receives 2014 Massachusetts Neuroscience Consortium Award

Carmela Abraham, PhD, professor of biochemistry and pharmacology at Boston University School of Medicine, was one of six recipients of this year's Massachusetts Neuroscience Consortium Award out of nearly 60 applicants. The grant was awarded to her for her work on multiple sclerosis and the role of the life extension protein Klotho in the limited repair of white matter in the disease.

7 Dec 2014

Three-drug combination produces better results in multiple myeloma patients

In the treatment of multiple myeloma, the addition of carfilzomib to a currently accepted two-drug combination produced significantly better results than using the two drugs alone, according to a worldwide research team led by investigators from Mayo Clinic.

7 Dec 2014

Novel treatments show safe responses in patients with relapsed, treatment-resistant blood cancers

Novel treatments that harness the body's own immune cells to attack cancer cells demonstrate safe and durable responses in patients with relapsed and treatment-resistant blood cancers, according to data presented today at the 56th American Society of Hematology Annual Meeting and Exposition.

7 Dec 2014

NIH Collaboratory provides guide to success for pragmatic clinical trials

Pragmatic clinical trials--real-life tests done in real-world settings--are increasingly important for answering pressing questions about how best to deliver health care. But these pragmatic trials require close collaboration between two professional groups who often have contrasting styles. One group is researchers, who follow structure like classical musicians. The other is and health care providers and administrators, who may need to improvise like jazz musicians.

6 Dec 2014

March of Dimes Celebration of Babies event raises record $1.1 million

March of Dimes, the leading non-profit organization for pregnancy and baby health, raised a record $1.1 million at their 9th annual March of Dimes Celebration of Babies: A Hollywood Luncheon event today at the Beverly Wilshire Hotel in Los Angeles. The 2014 honorees were actor/filmmaker Elizabeth Banks, who was presented with the March of Dimes Grace Kelly Award and Elizabeth Gabler, President, Fox 2000 who was named the March of Dimes Inspiring Woman of the Year.

6 Dec 2014

ACSM unveils strategic plan to improve health, fitness outcomes in Cincinnati

The American College of Sports Medicine, with support from the Anthem Blue Cross and Blue Shield Foundation, is expanding the ACSM American Fitness Index Technical Assistance Program to Cincinnati. Working with the Cincinnati Health Department's Creating Healthy Communities Coalition, ACSM unveiled a comprehensive strategic plan today that will guide the Cincinnati metro area toward improved health and fitness outcomes.

6 Dec 2014

Study links poor semen quality to higher risk of various health conditions

A study of more than 9,000 men with fertility problems has revealed a correlation between the number of different defects in a man's semen and the likelihood that the man has other health problems.

6 Dec 2014

Maria T. Lymberis to receive 2014 Gary S. Nye Award for Physician Health and Well-Being

Maria T. Lymberis, MD, a member of the Cooperative of American Physicians, Inc., will be honored with the 2014 Gary S. Nye Award for Physician Health and Well-Being for her longstanding commitment to physician health in her local community and in the state of California, as well as her career-long contributions to medical ethics.

6 Dec 2014

Ashish Nimgaonkar wins AGA-Boston Scientific Career Development Technology & Innovation Award

The American Gastroenterological Association Research Foundation is pleased to announce that Ashish Nimgaonkar, MBBS, MTech, MS, from John Hopkins University, has received the inaugural AGA-Boston Scientific Career Development Technology & Innovation Award. This award is graciously supported by a grant from Boston Scientific, a leading innovator of medical solutions.

5 Dec 2014

Janssen, American Diabetes Association team up to launch national educational campaign on diabetes

Janssen Pharmaceuticals, Inc. today announced a collaboration with the American Diabetes Association to launch Teaming Up to Take On Diabetes, a national educational campaign intended to help the nearly 30 million Americans living with diabetes better understand and manage the disease.

5 Dec 2014

New Crime Victims' Institute series explores human sex trafficking

Human sex trafficking is a serious problem both domestically and internationally and enhanced education is necessary to address the risk factors for entry into the sex trade, the physical and mental health consequences of victimization, and institutional responses to victims, according to a new series published by the Crime Victims' Institute at Sam Houston State University.

5 Dec 2014

Abstinence-induced changes in the brain could help predict relapse in smokers

Quitting smoking sets off a series of changes in the brain that Penn Medicine researchers say may better identify smokers who will start smoking again—a prediction that goes above and beyond today's clinical or behavioral tools for assessing relapse risk.

5 Dec 2014

Education News and Research

Nivolumab drug highly effective for Hodgkin's lymphoma

Study shows link between cardiac abnormalities, sudden unexpected death in epilepsy

New study explores reliability of optogenetics as method of intervention of temporal lobe seizures

Study provides insights into genetic underpinnings of childhood epilepsies

New treatment combinations improve outcomes for vulnerable patient with hard-to-treat disease

Scientists devise powerful algorithm to improve effectiveness of research technology harnessing RNAi

Study: Key protein may help prevent tumor growth, promote wound healing

Pediatric concussions increase significantly between 2003 and 2010 in Ontario

BUSM's Carmela Abraham receives 2014 Massachusetts Neuroscience Consortium Award

Three-drug combination produces better results in multiple myeloma patients

Novel treatments show safe responses in patients with relapsed, treatment-resistant blood cancers

NIH Collaboratory provides guide to success for pragmatic clinical trials

March of Dimes Celebration of Babies event raises record $1.1 million

ACSM unveils strategic plan to improve health, fitness outcomes in Cincinnati

Study links poor semen quality to higher risk of various health conditions

Maria T. Lymberis to receive 2014 Gary S. Nye Award for Physician Health and Well-Being

Ashish Nimgaonkar wins AGA-Boston Scientific Career Development Technology & Innovation Award

Janssen, American Diabetes Association team up to launch national educational campaign on diabetes

New Crime Victims' Institute series explores human sex trafficking

Abstinence-induced changes in the brain could help predict relapse in smokers

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