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Sphere Fluidics closes $2 million USD (c. £1.5 million GBP) investment round

Sphere Fluidics, announced that is has closed a $2 million (circa £1.5 million) investment round.

From Fluidic Sciences and Sphere Bio 16 Oct 2019

Sphere Fluidics collaborates with Peak Analysis and Automation to increase throughput in antibody discovery and cell line development

Sphere Fluidics, and Peak Analysis and Automation, will collaborate to offer automated micro-plate handling capabilities for single cell analysis.

From Fluidic Sciences and Sphere Bio 16 Oct 2019

The Scientist names Cyto-Mine technology #1 in the Top 10 Innovations of 2018

We are delighted to announce that Cyto-Mine is one of the winners of The Scientist 2018 Top 10 Innovations!

From Fluidic Sciences and Sphere Bio 16 Oct 2019

Study: Natural loss of foot muscles in rodents shares similarities with skeletal muscle atrophy

New insight on how the natural loss of foot muscles occurred in rodents and other species during their evolution has been published today in the open-access journal eLife.

16 Oct 2019

Researcher explores biological processes that cause fertility problems in humans

With significant funding from the National Institutes of Health (NIH), a researcher at The University of Texas at Arlington is investigating fundamental biological processes that lead to fertility problems in humans.

16 Oct 2019

Study: Genetic differences in the immune system shape bacteria that colonize the digestive system

Genetic differences in the immune system shape the collections of bacteria that colonize the digestive system, according to new research by scientists at the University of Chicago.

16 Oct 2019

Inactive receptor prevents cancer drugs from reactivating the immune system

The aim of immunotherapies is to enable the immune system once again to fight cancer on its own. Drugs known as checkpoint inhibitors are already in clinical use for this purpose.

15 Oct 2019

Drug-light combination could offer better control over CAR T-cell treatments

Bioengineers at the University of California San Diego are a step closer to making CAR T-cell therapy safer, more precise and easy to control.

15 Oct 2019

Heavier babies more likely to develop childhood allergies

A new study shows that babies who weigh more at any gestational age have a higher risk of later developing food allergies or eczema in childhood. However, there was no increase in the risk of hay fever. The paper published in the Journal of Allergy and Clinical Immunology found that the risk of food allergy went up by 44% and of eczema by 17% for each kilogram of added weight. On the other hand, restricted growth in the womb appears to be protective.

15 Oct 2019

Researchers track cell family trees to discover their role in tissue scarring and liver disease

Researchers have discovered that a key cell type involved in liver injury and cancer consists of two cellular families with different origins and functions.

15 Oct 2019

Koalas protect their germline cells against retroviral attack

In a new study published in the journal Cell, scientists have found that koala DNA is protected against attack by retroviruses by a special type of immune response, which distinguishes foreign DNA from the host genome and destroys it before it can proliferate. This finding could help us understand both how koalas survive these infections, and the mechanics of adaptive gene change.

15 Oct 2019

Study explains why some people who take heart medication develop sore, aching muscles

A study from McMaster University has found a potential mechanism explaining why some people who take drugs to lower their cholesterol develop sore, aching muscles.

15 Oct 2019

Engineered communities of cells make long-distance calls

The search for effective biological tools is a marathon, not a sprint, even when the distances are on the microscale. A discovery at Rice University on how engineered communities of cells communicate is a long step in the right direction.

15 Oct 2019

CRISPR helps find difficult to detect cancer cells

Immunotherapy is one of the latest and most effective armaments against various types of cancers. Some of the immunotherapy drugs such as PD-1 inhibitor Keytruda from Merck can block certain proteins in the cancer cells that can make the cells invisible to the immune system normally. Some of the cancers cells can now develop other ways to disguise themselves from being killed by the immune system.

15 Oct 2019

New technique reveals how the brain responds to light signals received by the retina

In recent decades, scientists have learned a great deal about how different neurons connect and send signals to each other. But it's been difficult to trace the activity of individual nerve fibers known as axons, some of which can extend from the tip of the toe to the head.

15 Oct 2019

A protein could play key role in neurodegenerative diseases, research suggests

Research led by Queen Mary University of London and the University of Seville around one protein's role in regulating brain inflammation could improve our understanding of neurodegenerative diseases.

15 Oct 2019

UCLA researchers discover new way to eliminate leukemia stem cells

The introduction of the drug imatinib in 2001 revolutionized the treatment of a type of cancer called chronic myelogenous leukemia. In more than 80% of people with CML who received the drug, the disease went into complete remission.

15 Oct 2019

PerkinElmer introduces PG-Seq Rapid Non-Invasive PGT-A kit as alternative to IVF embryo biopsies

PerkinElmer, Inc., a global leader committed to innovating for a healthier world, today introduced its PG-Seq Rapid Non-Invasive Preimplantation Genetic Testing for Aneuploidy (PGT-A) kit. This solution tests spent embryo culture media for chromosomal abnormalities during in vitro fertilization treatment.

From Revvity 15 Oct 2019

Gene mutations in the ClC-2 chloride channel cause high blood pressure, kidney damage

When the adrenal gland produces too much aldosterone, this often leads to high blood pressure and kidney damage (hyperaldosteronism). It has only recently emerged that several patients harbor a mutation in the gene for the ClC-2 chloride channel.

15 Oct 2019

Researchers reveal mechanism involved in altering DNA methylation in cancer

Understanding the mechanisms that mediate widespread DNA damage in the cancer genome is of great interest to cancer physicians and scientists because it may lead to improved treatments and diagnosis. In this study, a multi-institutional team led by researchers at Baylor College of Medicine has brought attention to genomic structural variation as a previously unappreciated mechanism involved in altering DNA methylation, a form of gene control, in human cancers.

15 Oct 2019

Cell News and Research

Sphere Fluidics closes $2 million USD (c. £1.5 million GBP) investment round

Sphere Fluidics collaborates with Peak Analysis and Automation to increase throughput in antibody discovery and cell line development

The Scientist names Cyto-Mine technology #1 in the Top 10 Innovations of 2018

Study: Natural loss of foot muscles in rodents shares similarities with skeletal muscle atrophy

Researcher explores biological processes that cause fertility problems in humans

Study: Genetic differences in the immune system shape bacteria that colonize the digestive system

Inactive receptor prevents cancer drugs from reactivating the immune system

Drug-light combination could offer better control over CAR T-cell treatments

Heavier babies more likely to develop childhood allergies

Researchers track cell family trees to discover their role in tissue scarring and liver disease

Koalas protect their germline cells against retroviral attack

Study explains why some people who take heart medication develop sore, aching muscles

Engineered communities of cells make long-distance calls

CRISPR helps find difficult to detect cancer cells

New technique reveals how the brain responds to light signals received by the retina

A protein could play key role in neurodegenerative diseases, research suggests

UCLA researchers discover new way to eliminate leukemia stem cells

PerkinElmer introduces PG-Seq Rapid Non-Invasive PGT-A kit as alternative to IVF embryo biopsies

Gene mutations in the ClC-2 chloride channel cause high blood pressure, kidney damage

Researchers reveal mechanism involved in altering DNA methylation in cancer

What are the challenges of cell line development? eBook

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