Genes News and Research

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Scientists describe elaborate system of gene control triggered by chemical damage to DNA

Scientists describe for the first time a web of inter-related responses that cells use to avoid becoming diseased or cancerous after being exposed to a powerful mutagen.

7 Jun 2006

Centrosomes may contain ribonucleic acid

Despite more than a century of study, scientists know relatively little about the inner workings of centrosomes - organelles essential to cell division in humans and animals.

7 Jun 2006

Gene mutation potentially involved in breast cancer initiation

Researchers have found evidence suggesting that a mutation in a gene that normally helps block the formation of breast tumors could play a role in the initiation of a major form of breast cancer.

6 Jun 2006

Researchers increase bone mass by tweaking the shape of a regulatory protein

Howard Hughes Medical Institute (HHMI) researchers at Stanford University have found that they can increase bone mass in mice by tweaking the shape of a regulatory protein.

6 Jun 2006

New findings offer hope for vaccine against AIDS

AIDS patients' failure to clear HIV-1 might not be due to the inability of the human immune system to recognise the virus, as was previously thought.

6 Jun 2006

Researchers discover the presence of the genetic material RNA in the centrosome

Researchers have discovered the presence of the genetic material RNA in the centrosome, the organizing structure inside each cell that assures proper cell division.

6 Jun 2006

Potential new treatment for diabetic nerve damage

A potentially ground-breaking treatment for nerve damage caused by diabetes has shown promising results in preclinical and early patient trials.

From The University of Manchester 6 Jun 2006

Sunitinib therapy shows promise in children with metastatic gastrointenstinal stromal tumor

Children with a rare digestive-tract cancer that is resistant to front-line therapy have benefited from a newer targeted therapy that has been shown effective in adults, according to data from a small pilot study.

5 Jun 2006

Milstein gift seeks cure for antibiotic-resistant TB and malaria

A $7.25 million gift to Weill Medical College of Cornell University will establish the Abby and Howard P. Milstein Chemistry Core Facility and the Abby and Howard P. Milstein Program in Chemical Biology.

5 Jun 2006

Genes variations raise risk of heart disease after treatment for childhood cancer

Gene variations may raise the risk that survivors of childhood cancer will suffer congestive heart failure as a complication of drugs they received during cancer treatment.

5 Jun 2006

Humans are a cocktail of bacteria and human cells

Gene experts after studying the DNA of hundreds of different kinds of bacteria in the human gut have reached the conclusion that the human race may not be quite as human as we may think.

4 Jun 2006

Pituitary adenoma predisposition caused by germline mutations in the AIP gene

A recent Finnish study identifies a low-penetrance gene defect which predisposes carriers to intracranial tumors called pituitary adenomas. In particular individuals carrying the gene defect are susceptible to such tumors which secrete growth hormone.

1 Jun 2006

Nepalese Rhesus monkeys may provide new alternative for HIV/AIDS research

Rhesus monkeys in Nepal may provide a suitable alternative to alleviate a critical shortage of laboratory animals used in work to develop vaccines against diseases such as HIV/AIDS.

1 Jun 2006

Molecular pathway may contribute to age related diseases

A common molecular denominator in aging and many age-related diseases is oxidative stress.

1 Jun 2006

Two specific genes, Wnt4 and Fgf9 fight to determine sexual differentiation

Whether or not a fertilized mammalian egg ultimately develops into a male or female is determined by the winner of a tug of war between two different genes encoding signaling proteins and the divergent pathways they control.

1 Jun 2006

Scientists gain better understanding of Proteus mirabilis

Scientists now have inside information to use in the fight against Proteus mirabilis - a nasty bacterium that can cause kidney stones, as well as hard-to-treat urinary tract infections.

1 Jun 2006

Scientists use "small interfering RNAs" to block the spread of human colorectal cancer cells

Using one of the newest and most powerful tools of biomedical science, University of Texas Medical Branch at Galveston (UTMB) researchers have scored a dramatic success in the battle against colorectal cancer.

1 Jun 2006

Molecular diagnostic test for early-stage breast cancer

Researchers at Montefiore Medical Center are leading a nationwide clinical trial to determine whether a new genetic test can be used to personalize treatment for early-stage breast cancer.

1 Jun 2006

Exposure to environmental estrogens during development of the prostate gland in the male fetus may lead to later prostate cancer risk

A study in the June 1 issue of Cancer Research presents the first evidence that exposure to low doses of environmental estrogens during development of the prostate gland in the male fetus may result in a predisposition to prostate cancer later in life.

1 Jun 2006

Promising new vaccine delivery approach

The field of vaccine development is getting a boost from new research that has identified a promising vaccine delivery approach, which in animal studies produced long-term immune protection after just one immunization.

31 May 2006