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Receptor that detects heat of red chili pepper may help protect the brain after TBI

A receptor on our immune cells that can detect both the heat of a red chili pepper and the extreme physical heat of a pizza oven may help protect the brain following a traumatic brain injury, scientists say.

13 Apr 2018

Lithuanian researchers use freeze-drying technique to create sponge-like wound dressings

Group of researchers at Kaunas University of Technology, Lithuania are developing new generation sponge-like wound dressings with hyaluronic acid. Antimicrobial, antioxidant, anti-inflammatory wound dressings stimulate tissue regeneration and can be especially efficient in treating deep wounds that are difficult to heal.

12 Apr 2018

Research team identifies new mutation behind heart failure in South Asians

An international research team involving Karolinska Institutet has identified a new mutation in South Asians that, in combination with a known mutation in the same gene, increases the risk of cardiomyopathy and heart failure.

12 Apr 2018

Breast cancers more likely to spread after surgery finds study

Breast cancer patients are more likely to experience a return and spread of their cancer within 18 months after a mastectomy or removal of the breast tumour along with healthy breast tissues. The reason for this or this association has been hitherto unexplained. According to a new study from MIT and the Whitehead Institute, the process of healing of the surgical scar after surgery is the cause for spread of the cancer.

12 Apr 2018

Patient's mucus may help predict type of chronic sinusitis

By April, nearly one-third of the U.S. is already experiencing high pollen levels while the weather and temperatures continue to fluctuate, aggravating sinus symptoms. A patient's mucus may predict the type of his or her chronic sinusitis, which could help doctors determine whether surgery or medical treatments can produce the best outcomes, according to a recently published Vanderbilt study.

9 Apr 2018

Analysis does not reveal consistent link between NSAIDs use and exacerbation of inflammatory bowel disease

Contrary to generally accepted belief, a recent review and analysis of published studies did not reveal a consistent association between the use of nonsteroidal anti-inflammatory drugs (NSAIDs) or acetaminophen and exacerbation of Crohn's disease and ulcerative colitis.

5 Apr 2018

Researchers find unexpected anti-inflammatory effects in PCSK9 inhibitors

PCSK9 inhibition is a new therapeutic strategy for atherosclerosis which is known to lower LDL cholesterol.

5 Apr 2018

Two new studies highlight GABA's importance in type 1 and type 2 diabetes

Dynamic interactions between the nervous system, hormones and the immune system are normally on-going but in diabetes the balance is disturbed.

5 Apr 2018

Microscopic revelations could lead to new treatment options for deadly blood infections

Researchers at the University of Calgary's Cumming School of Medicine (CSM) have for the first time been able to observe -- live and in real-time -- how the human body responds to often lethal fungal blood infections in the lung.

4 Apr 2018

BWH bioengineers develop flare-responsive hydrogel to treat arthritis

Arthritis flares - the unpredictable and often sudden worsening of arthritis symptoms -- can be debilitating. These episodes can make the management of inflammatory arthritis, which includes rheumatoid arthritis and psoriatic arthritis, challenging for patients and physicians.

3 Apr 2018

Macrophages stimulated to produce potent anti-inflammatory molecule

Researchers have discovered that macrophages, which play a key role in inflammation, also produce an anti-inflammatory molecule called itaconate.

29 Mar 2018

Daily regimen of ibuprofen can ward off Alzheimer's disease, say neuroscientists

A Vancouver-based research team led by Canada's most cited neuroscientist, Dr. Patrick McGeer, has successfully carried out studies suggesting that, if started early enough, a daily regimen of the non-prescription NSAID (nonsteroidal anti-inflammatory drug) ibuprofen can prevent the onset of Alzheimer's disease.

26 Mar 2018

NSAID use linked to increased risk of atrial fibrillation

Use of nonsteroidal anti-inflammatory drugs (NSAIDs) was associated with an 18% increased risk of atrial fibrillation—an irregular, often rapid heart rate—in a study of middle-aged adults in Taiwan. The findings are published in the British Journal of Clinical Pharmacology.

21 Mar 2018

Study shows that omega-6 fatty acids could protect against premature death

Could omega-6 fatty acids protect you against premature death? The answer is yes, according to a new University of Eastern Finland study. While protecting against death, omega-6 fatty acids also keep cardiovascular diseases at bay.

19 Mar 2018

$Long-term PPI use not linked to increased hip fracture risk among Alzheimer's patients$

Long-term PPI use not linked to increased hip fracture risk among Alzheimer's patients

Long-term proton pump inhibitor (PPI) use does not increase the risk of hip fracture among persons with Alzheimer's disease, according to a new study from the University of Eastern Finland.

13 Mar 2018

New study examines origin of cryptococcosis within the central nervous system

A particular fungal infection is responsible for more than 220,000 cases of cryptococcosis worldwide each year in people with HIV and AIDS, with nearly 181,000 of those resulting in death.

8 Mar 2018

Parasitic tapeworm could someday help prevent or treat pediatric IBD

New research suggests that parasitic worms could someday help prevent or treat pediatric inflammatory bowel disease (IBD). The study, published ahead of print in the American Journal of Physiology-Gastrointestinal and Liver Physiology, was chosen as an APSselect article for March.

2 Mar 2018

Inflammatory bowel disease linked to elevated risk of heart attack

An analysis of medical-record data from more than 17.5 million patients found that people with inflammatory bowel disease (IBD) are at elevated risk for a heart attack, regardless of whether or not they have traditional risk factors for heart disease such as high cholesterol, high blood pressure and smoking.

1 Mar 2018

Celgene announces regulatory information about investigational compound for relapsing multiple sclerosis

Celgene Corporation today announced that it has received a Refusal to File letter from the United States Food and Drug Administration regarding its New Drug Application for ozanimod in development for the treatment of patients with relapsing forms of multiple sclerosis.

27 Feb 2018

New study lays foundation to obtain apple cubes enriched with probiotics

Researchers of the Universitat Politècnica de València and the Universidade Federal do Ceará (Brazil) have completed a study that lays the foundation to obtain apple cubes enriched with probiotics, namely Lactobacillus casei. The work has been published in the most recent edition of the Journal of Functional Foods.

27 Feb 2018