immunity News and Research

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New cold perfusion approach to isolate hepatic stellate cells from fatty liver-associated tumors

Obesity can give rise to a variety of health concerns. Nonalcoholic steatohepatitis (NASH) - a type of fatty liver disease that might progress to cancer - is particularly prevalent among obese people.

12 Sep 2022

Review: Arthritogenic alphaviruses and host type I IFN responses

Announcing a new article publication for Zoonoses journal. Arthritogenic alphaviruses, such as Ross River virus, chikungunya virus and O'nyong-nyong virus, cause endemic disease globally and are a major public health concern.

12 Sep 2022

Are antibodies induced by historic smallpox vaccination cross-reactive with the monkeypox virus?

esearchers measured the monkeypox virus-neutralizing antibodies produced by the vaccinia virus vaccine, modified vaccinia virus Ankara vaccine, and monkeypox virus to understand the efficacy of the MVA-Bavarian Nordic vaccine currently being used against monkeypox.

12 Sep 2022

Did the US jump the gun with the new omicron-targeted vaccines?

Last month, the FDA authorized omicron-specific vaccines, accompanied by breathless science-by-press release and a media blitz.

12 Sep 2022

Dissecting vaccinia virus and monkeypox virus-specific T cell responses in humans

In a new study, a team of researchers studied different antigens targeted by vaccinia virus (VACV)- and monkeypox virus (MPXV)-specific T cells.

12 Sep 2022

SARS-CoV-2 Omicron BA.4.6 resistant to many therapeutic monoclonal antibodies in clinical use

In a recent study posted to the bioRxiv* preprint server, researchers in Taiwan and the United States explore the resistance of a newly emergent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sub-variant BA.4.6 to the therapeutic monoclonal antibodies currently being used to treat coronavirus disease 2019 (COVID-19).

12 Sep 2022

Self-replicating intradermal RNA vaccine against SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, researchers assessed the efficiency of a controllable self-replicating ribonucleic acid (c-srRNA) vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

12 Sep 2022

Vaccinia virus-based vaccines mount a robust immune response against the monkeypox virus

New research has suggested that recommended vaccinia virus (VACV)-based vaccines will mount a robust immune response against the monkeypox virus observed in the current outbreak (MPXV-2022).

12 Sep 2022

Brain injury a common consequence of both COVID-19 and influenza

In a recent study published in the journal Brain, researchers reported that brain injury is common in coronavirus disease 2019 (COVID-19) and influenza.

12 Sep 2022

Tumor-derived factors stimulate effector trogocytosis and inhibit CAR T cells

The immune system is equipped to respond not just to external invaders - think viruses, bacteria, and parasites - but also to internal threats, namely, cancer. Yet, frequently, malignancies overcome the immune system's defenses and evade detection.

12 Sep 2022

Antibody escape less pronounced with BA.2.75 compared to BA.4/5

In a recent study published in the Lancet, researchers evaluated the antibody neutralization sensitivity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.2.75 subvariant.

11 Sep 2022

A new monkeypox vaccine is needed to prevent global transmission

In a recent study published in the journal Vaccines, scientists reviewed all relevant literature to find the available vaccines and therapeutics to prevent MPV.

11 Sep 2022

Novel antifungal medications urgently needed to control COVID-19-associated fungal infections

Every day we inhale thousands of potentially pathogenic fungal spores, but our immune system simply eliminates them.

9 Sep 2022

Duke researchers identify chlamydia’s stealthy cloaking device

Chlamydia, the leading cause of sexually transmitted bacterial infections, evades detection and elimination inside human cells by use of a cloaking device. But Duke University researchers have grasped the hem of that invisibility cloak and now hope they can pull it apart.

9 Sep 2022

Distribution of platinum after chemotherapy may help predict resistance to ovarian cancer treatment

A team of researchers from Japan has discovered that the distribution of platinum within a tumor following platinum-based chemotherapy treatment of ovarian cancer may predict whether the tumor will be resistant to further treatment.

9 Sep 2022

Monkeypox can sometimes lead to encephalitis, confusion or seizures

Monkeypox can sometimes lead to neurological complications such as encephalitis (brain inflammation), confusion or seizures, finds a new review of evidence led by a UCL researcher.

9 Sep 2022

Scientists observe how SARS-CoV-2 protein dismantles critical immunity pathway

Over the past two years, scientists have studied the SARS-CoV-2 virus in great detail, laying the foundation for developing COVID-19 vaccines and antiviral treatments.

9 Sep 2022

Research on the antimicrobial effects of human milk oligosaccharides

In a recent review published in the journal Current Opinion in Chemical Biology, researchers discussed the latest advances in the antimicrobial properties of human milk.

9 Sep 2022

Study provides a potential game-changer in assessing treatment response in pancreatic cancer patients

The statistics for pancreatic cancer are sobering. With a five-year survival rate of only 9%, incidence of the most common type, pancreatic ductal adenocarcinoma (PDAC), is growing and projected to be the second cause of cancer deaths by 2030.

8 Sep 2022

Promising anti-cancer agent may also prevent SARS-CoV-2 from replication

Based on findings from a new study by a Johns Hopkins Medicine-led research team, an effective means of fighting SARS-CoV-2, the virus that causes COVID-19, may be possible that circumvents the problem of waning immunity often observed when current vaccines deal with emerging COVID variants.

8 Sep 2022

immunity News and Research

New cold perfusion approach to isolate hepatic stellate cells from fatty liver-associated tumors

Review: Arthritogenic alphaviruses and host type I IFN responses

Are antibodies induced by historic smallpox vaccination cross-reactive with the monkeypox virus?

Did the US jump the gun with the new omicron-targeted vaccines?

Dissecting vaccinia virus and monkeypox virus-specific T cell responses in humans

SARS-CoV-2 Omicron BA.4.6 resistant to many therapeutic monoclonal antibodies in clinical use

Self-replicating intradermal RNA vaccine against SARS-CoV-2

Vaccinia virus-based vaccines mount a robust immune response against the monkeypox virus

Brain injury a common consequence of both COVID-19 and influenza

Tumor-derived factors stimulate effector trogocytosis and inhibit CAR T cells

Antibody escape less pronounced with BA.2.75 compared to BA.4/5

A new monkeypox vaccine is needed to prevent global transmission

Novel antifungal medications urgently needed to control COVID-19-associated fungal infections

Duke researchers identify chlamydia’s stealthy cloaking device

Distribution of platinum after chemotherapy may help predict resistance to ovarian cancer treatment

Monkeypox can sometimes lead to encephalitis, confusion or seizures

Scientists observe how SARS-CoV-2 protein dismantles critical immunity pathway

Research on the antimicrobial effects of human milk oligosaccharides

Study provides a potential game-changer in assessing treatment response in pancreatic cancer patients

Promising anti-cancer agent may also prevent SARS-CoV-2 from replication

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