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Study shows that SRC-3 also regulates human immune T regulatory cells

A study led by researchers at Baylor College of Medicine reveals a novel role of the steroid receptor coactivator 3 (SRC-3/NCOA3), a protein crucial for steroid hormone function and a prognostic marker for aggressive human breast and other cancers.

12 Feb 2021

People previously infected with COVID-19 respond strongly to one dose of Pfizer vaccine

Although clinical trial data are encouraging, real-world evidence with regard to the COVID-19 vaccine remains scarce. In particular, response to the vaccine among those previously infected with SARS-CoV-2 is still not completely understood.

12 Feb 2021

Opioid use during pregnancy can cause long-lasting impairment in the infant's brain

As the number of pregnant women using opioid drugs continues to rise, questions have been raised about the long-term health effects on children exposed to these drugs in the womb.

12 Feb 2021

Researchers identify a pathway used by filoviruses to enter cells

It was once thought that Ebola and related filoviruses were more or less contained to Central Africa.

11 Feb 2021

Ionic liquid formulation kills cancer cells, allows uniform distribution of chemotherapy to tumors

A Mayo Clinic team, led by Rahmi Oklu, M.D., Ph.D., a vascular and interventional radiologist at Mayo Clinic, in collaboration with Samir Mitragotri, Ph.D., of Harvard University, report the development of a new ionic liquid formulation that killed cancer cells and allowed uniform distribution of a chemotherapy drug into liver tumors and other solid tumors in the lab.

11 Feb 2021

Non-symptomatic cases contribute to at least 50% of SARS-CoV-2 infection

A new study out of the University of Chicago has found that during the initial wave of the COVID-19 outbreak in New York City, only 1 in 5 to 1 in 7 cases of the virus was symptomatic.

11 Feb 2021

Research reveals vital clues for discovery of COVID-19 drugs

Research from the University of Kent, Goethe-University in Frankfurt am Main, and the Philipps-University in Marburg has provided crucial insights into the biological composition of SARS-CoV-2, the cause of COVID-19, revealing vital clues for the discovery of antiviral drugs.

11 Feb 2021

Addressing the health impacts of structural racism in racial and ethnic disparities research

Structural racism is a public health crisis in the U.S. and worldwide. The scientific publishing community can improve our understanding and address the significant health impacts of structural racism in racial and ethnic disparities research.

11 Feb 2021

Scent detection dogs can be used to screen and identify COVID-19-infected individuals

In a recent article in the Journal of Osteopathic Medicine, authors gathered previously published research to summarize current thinking on the feasibility and efficacy of using scent detection dogs to screen for the COVID-19 virus.

11 Feb 2021

STING activation may be a new approach to reduce graft-versus-host disease

MUSC Hollings Cancer Center researcher Yongxia Wu, Ph.D., identified a new target molecule in the fight against graft-versus-host disease (GVHD).

11 Feb 2021

Use of mobile stroke units linked to improved clinical outcomes

STEMOs (Stroke-Einsatz-Mobile) have been serving Berlin for ten years. The specialized stroke emergency response vehicles allow physicians to start treating stroke patients before they reach hospital.

11 Feb 2021

Duration of delirium in critically ill patients predicts mortality and disability

Delirium, a form of acute brain dysfunction, is widespread in critically ill patients in lower resourced hospitals, and the duration of delirium predicted both mortality and disability at six months after discharge, according to a study published in PLOS ONE.

11 Feb 2021

UC San Diego and County of San Diego test early alert system to detect SARS-CoV-2 at schools

In an effort to help schools reduce the risk of COVID-19 outbreaks as they resume in-person instruction, University of California San Diego and the County of San Diego are testing the Safer at School Early Alert system, an evidence-informed program to detect SARS-CoV-2 at schools and child care centers.

11 Feb 2021

New urine test could avoid unnecessary prostate cancer biopsies

A urine test based on University of Michigan Rogel Cancer Center research could have avoided one third of unnecessary prostate cancer biopsies while failing to detect only a small number of cancers, according to a validation study that included more than 1,500 patients.

11 Feb 2021

Researchers discover previously-unknown function in enzyme critical for cancer growth

Considered the most lethal form of DNA damage, double-strand breaks must be repaired to prevent cell death. In developing therapies for hard-to-treat breast and ovarian cancers in patients with BRCA gene mutations, scientists aim to identify ways to keep cancer cells from using DNA break repair pathways.

11 Feb 2021

Genomic test may help guide treatment decisions for patients with recurrent prostate cancer

A commercially available genomic test may help oncologists better determine which patients with recurrent prostate cancer may benefit from hormone therapy, according to new research from the Johns Hopkins Kimmel Cancer Center and 15 other medical centers.

11 Feb 2021

HIV self-testing increases testing uptake and frequency in trans people

HIV self-testing could reduce the time between HIV infection and HIV diagnosis amongst trans people when compared to standard testing services, suggests new research in EClinicalMedicine.

11 Feb 2021

Short duration, poor-quality sleep may increase risk of dementia and earlier death in elderly people

Sleep and health are inextricably connected. New research from investigators at Brigham and Women's Hospital explores the connection between sleep disturbances and deficiencies among older adults and risk of dementia and death, finding that risk of dementia was double among participants who reported getting less than five hours of sleep compared to those who reported 7-8 hours of sleep per night.

11 Feb 2021

Variants of nine genes induce a higher risk of developing Addison's disease

Variants of nine genes increase the risk of developing Addison's disease, a rare disease in which the immune system attacks the adrenal glands.

11 Feb 2021

Tech companies mobilize to schedule vaccine appointments, but often fall short

On Jan. 14 at 8:43 p.m., Patrick McKenzie tweeted a plea for tech engineers to help him set up a website to track covid-19 vaccine availability in California. McKenzie, who heads a Bay Area financial services tech company, issued the call to "anyone in California [who] wants to do a civtech project which matters."

11 Feb 2021

Medicine News and Research

Study shows that SRC-3 also regulates human immune T regulatory cells

People previously infected with COVID-19 respond strongly to one dose of Pfizer vaccine

Opioid use during pregnancy can cause long-lasting impairment in the infant's brain

Researchers identify a pathway used by filoviruses to enter cells

Ionic liquid formulation kills cancer cells, allows uniform distribution of chemotherapy to tumors

Non-symptomatic cases contribute to at least 50% of SARS-CoV-2 infection

Research reveals vital clues for discovery of COVID-19 drugs

Addressing the health impacts of structural racism in racial and ethnic disparities research

Scent detection dogs can be used to screen and identify COVID-19-infected individuals

STING activation may be a new approach to reduce graft-versus-host disease

Use of mobile stroke units linked to improved clinical outcomes

Duration of delirium in critically ill patients predicts mortality and disability

UC San Diego and County of San Diego test early alert system to detect SARS-CoV-2 at schools

New urine test could avoid unnecessary prostate cancer biopsies

Researchers discover previously-unknown function in enzyme critical for cancer growth

Genomic test may help guide treatment decisions for patients with recurrent prostate cancer

HIV self-testing increases testing uptake and frequency in trans people

Short duration, poor-quality sleep may increase risk of dementia and earlier death in elderly people

Variants of nine genes induce a higher risk of developing Addison's disease

Tech companies mobilize to schedule vaccine appointments, but often fall short

Everything there is to know about biosimilars eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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