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University Hospitals Seidman Cancer Center launches new CAR-T therapy trial

University Hospitals Seidman Cancer Center launched a new clinical trial for CAR-T, joining a select group of hospitals offering the therapy and a smaller group of hospitals manufacturing the CAR-T cells.

14 Aug 2018

E-cigarettes not so safe but still better than cigarettes

According to latest research vaping using e-cigarettes can hasten the death of lung cells by up to fifty times and cause serious lung diseases later in life. This latest study was published in the journal Thorax.

14 Aug 2018

Duke researchers track missing T-cells in glioblastoma patients

Glioblastoma brain tumors can have an unusual effect on the body's immune system, often causing a dramatic drop in the number of circulating T-cells that help drive the body's defenses.

13 Aug 2018

Platelet-rich plasma does not enhance cartilage formation capabilities of stem cells

Platelet-rich plasma is believed to provide pain relief and help improve joint function in degenerative joint disease, but a new study has shown that it does not act by promoting stem cell proliferation or enhance the cartilage formation capabilities of mesenchymal stem cells

13 Aug 2018

Altered nitrogen metabolism may contribute to emergence of new cancer mutations

Nitrogen is a basic building block of all the body's proteins, RNA and DNA, so cancerous tumors are greedy for this element. Researchers at the Weizmann Institute of Science, in collaboration with colleagues from the National Cancer Institute and elsewhere, have now shown that in many cancers, the patient's nitrogen metabolism is altered, producing detectable changes in the body fluids and contributing to the emergence of new mutations in cancerous tissue.

13 Aug 2018

Researchers discover secret communication hotline between breast cancers and normal cells

Australian researchers have uncovered a secret communication hotline between breast cancers and the normal cells surrounding them. Importantly, the messages sent back and forth between the normal and tumour cells encourage the cancer to survive and to become more aggressive.

13 Aug 2018

Discovery could lead to new drugs against infection and inflammation

Researchers at Lund University in Sweden, have in collaboration with colleagues in Copenhagen and Singapore, mapped how the body's own peptides act to reduce infection and inflammation by deactivating the toxic substances formed in the process.

13 Aug 2018

UAB study shows how ion channel differentiates newborn and mature neurons in the brain

The dentate gyrus of the hippocampus is part of the brain that helps form memories. It is also one of just two areas in the adult brain where new neurons are continuously formed.

13 Aug 2018

MSU researchers uncover the effects of aging on regenerative ability of kidneys

Autophagy is a process of destruction and processing of damaged cell components by the cells themselves. It is used by a cell to clean itself of excessive organelles and sometimes for self-execution. This adaptive mechanism supports a healthy phenotype on the cellular level.

13 Aug 2018

NIH awards $6.5 million to establish multi-institution biomedical technology resource center

The National Institutes of Health have awarded $6.5 million to a consortium that includes the Icahn Institute for Genomics and Multiscale Biology at the Icahn School of Medicine at Mount Sinai, the University of Washington, the University of Connecticut, and the University of Auckland, New Zealand, to establish the Center for Reproducible Biomedical Modeling.

13 Aug 2018

Autoimmune response contributes to vision loss in glaucoma patients

A research team from Massachusetts Eye and Ear and MIT has shown that immune cells in the eye that developed in response to early exposure to bacteria are a key contributor to progressive vision loss from glaucoma, the second leading cause of irreversible blindness in the world.

10 Aug 2018

Novel blood-based marker may help predict kidney cancer years before clinical diagnosis

A critical biomarker of kidney disease may help predict clear cell kidney cancer - the most common form of kidney cancer - years before clinical diagnosis. Kidney-injury-molecule-1 can be detected in the urine and blood and is generally present at low levels in healthy individuals.

10 Aug 2018

Researchers uncover new details in how the olfactory epithelium develops

Dogs, known for their extraordinarily keen senses of smell, can be trained to use their sensitive sniffers to find drugs, bombs, bed bugs, missing hikers and even cancer. Among dogs and other animals that rely on smell, at least one factor that may give them an advantage is a sheet of tissue in the nasal cavity.

10 Aug 2018

PARP inhibitors show promise for treating and preventing brain disorders

A class of cancer drugs called PARP inhibitors could be useful for treating and preventing brain disorders, including amyotrophic lateral sclerosis, also called Lou Gehrig's disease, and some forms of frontotemporal degeneration, by halting the misplacement of specific proteins that affect nerve cells, according to a study published in Molecular Cell by researchers in the the School of Arts and Sciences and the Perelman School of Medicine at the University of Pennsylvania.

10 Aug 2018

Researchers find potential therapeutic target for treating obesity and diabetes

A newly published study by researchers from the University of Colorado School of Medicine has identified a potential therapeutic target for treating obesity and diabetes.

10 Aug 2018

Biomarkers responsible for exhaustion in cancer linked to fatigue in Parkinson's disease

Biological markers responsible for extreme exhaustion in patients with cancer have now been linked to fatigue in those with Parkinson's disease, according to new research from Rice University.

10 Aug 2018

Scientists define key binding characteristics of protein associated with heart disease and breast cancer

Galectins attach to other proteins via the carbohydrates on their surfaces (sugar-binding proteins). As such they impact on a range of processes in the cell associated with a number of diseases, including heart disease and breast cancer – the most common cancer in women worldwide, with 1.7 million new cases diagnosed in 2012 alone.

10 Aug 2018

B Cell News and Research

University Hospitals Seidman Cancer Center launches new CAR-T therapy trial

E-cigarettes not so safe but still better than cigarettes

Duke researchers track missing T-cells in glioblastoma patients

Platelet-rich plasma does not enhance cartilage formation capabilities of stem cells

Altered nitrogen metabolism may contribute to emergence of new cancer mutations

Researchers discover secret communication hotline between breast cancers and normal cells

Discovery could lead to new drugs against infection and inflammation

UAB study shows how ion channel differentiates newborn and mature neurons in the brain

MSU researchers uncover the effects of aging on regenerative ability of kidneys

NIH awards $6.5 million to establish multi-institution biomedical technology resource center

Autoimmune response contributes to vision loss in glaucoma patients

Novel blood-based marker may help predict kidney cancer years before clinical diagnosis

Researchers uncover new details in how the olfactory epithelium develops

PARP inhibitors show promise for treating and preventing brain disorders

Researchers find potential therapeutic target for treating obesity and diabetes

Biomarkers responsible for exhaustion in cancer linked to fatigue in Parkinson's disease

Scientists define key binding characteristics of protein associated with heart disease and breast cancer

Study: Rare lymphoid cells play key role in development of inflammatory arthritis

One-two punch of powerful antibodies may be best way to stop Ebola virus

GSS sensors provide stable CO2 control for laboratory incubator applications

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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