Infectious Diseases News and Research

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WVU researchers use machine learning and GIS to predict where COVID-19 testing will be most crucial

The National Institutes of Health has called COVID-19 testing "the key to getting back to normal." Yet testing rates have dropped nationwide, even as the Delta and Omicron variants accelerated the virus' spread.

10 Mar 2022

Single dose of new drug nirsevimab provides safe protection against RSV in healthy infants

The new drug nirsevimab showed 74.5 percent efficacy against medically attended lower respiratory tract infections caused by respiratory syncytial virus (RSV) in healthy infants, according to an international, randomized, placebo-controlled phase 3 clinical trial published in the New England Journal of Medicine.

9 Mar 2022

IPD pooled analysis quantifies the underlying hematological response following malaria infection

A new malaria study using a very large analysis of pooled individual patient data (IPD) from more than 70,000 patients of all ages, has been published today in BMC Medicine.

9 Mar 2022

Increasing trend of antimicrobial resistance in Eastern Mediterranean Region of World Health Organization

Researchers investigated the rising antimicrobial resistance in the Eastern Mediterranean Region of the World Health Organization from 2017 to 2019.

9 Mar 2022

Mathematical model for evaluating factors driving SARS-CoV-2 transmission and pathogenesis

A new study provides an overview of the use of mathematical modeling to determine severe acute respiratory syndrome coronavirus 2 kinetics.

9 Mar 2022

Study suggests recent common cold may actually lead to worse COVID-19 disease

A new study published in the Journal of Infectious Diseases shines an unexpected light on the notion that pre-existing immunity to common cold coronaviruses can protect us from coronavirus disease 2019 (COVID-19) – and reveals that this may actually put certain individuals at risk of more severe clinical presentations.

8 Mar 2022

Thermostable next-generation vaccine candidate against SARS-CoV-2 variants of concern studied in mice

Researchers developed a highly thermo-tolerant vaccine candidate that elicited high nAb titers in mice against several SARS-CoV-2 variants of concerns.

8 Mar 2022

Study to examine the risks for brain disorders from repetitive head impacts in contact sports

Internationally-renowned researchers from Boston University and the University of California, San Francisco) are launching a new study, called the Head Impact & Trauma Surveillance Study (HITSS).

7 Mar 2022

The relative dynamics of infection with the Delta and Omicron SARS-CoV-2 variants in aged and young Syrian hamsters

Researchers demonstrated the relative pathogenicity of SARS-CoV-2 Omicron and Delta variants of concern in Syrian hamsters.

7 Mar 2022

Microneedle treatments could significantly desensitize people with food allergies

Treating peanut allergy with microneedles could significantly improve desensitization by directly targeting the allergen to the skin, providing greater protection from severe allergic reactions for millions of people, a new study suggests.

4 Mar 2022

Over a third vaccinated-but-unboosted adults have reservations about vaccinating children

While the vast majority of U.S. adults who are fully vaccinated and boosted against Covid-19 would be likely to recommend vaccinating a 5- to 11-year-old, over a third of fully vaccinated adults who have not had a booster shot have reservations about Covid-19 vaccination for a child that age, according to survey data analysis by the Annenberg Public Policy Center of the University of Pennsylvania.

3 Mar 2022

Study shows the impact of COVID-19 restrictions on dengue cases in 2020

Nearly three quarters of a million fewer global cases of dengue occurred in 2020, which could be linked to COVID-19 disruptions limiting human mobility and contact, according to a new study published in Lancet Infectious Diseases.

3 Mar 2022

First dose SARS-CoV-2 vaccination coverage among younger children in America

Researchers recently investigated the differences in first dose coverage of coronavirus disease 2019 vaccination among children aged five to 11 years in the United States.

3 Mar 2022

Study explores coronavirus surveillance in bats from Argentina

In a new study, researchers monitored the circulation of coronaviruses in bats from the central and northern provinces of Argentina.

3 Mar 2022

Some oral bacteria associated with development of high blood pressure in postmenopausal women

Some oral bacteria were associated with the development of hypertension, also known as high blood pressure, in postmenopausal women, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

2 Mar 2022

Researchers reveal unique signature of genes expressed by hematopoietic stem cells

Hematopoietic stem cells (HSCs) have the capacity to both self-renew and differentiate into all mature blood cell types, making them promising treatments for a variety of diseases.

2 Mar 2022

Targeting necroptosis using a necroptosis inhibitor lessens myositis-induced muscle weakness

A new study has suggested that treatment to target necroptosis in muscle fibers using a necroptosis inhibitor lessens myositis-induced muscle weakness as well as muscle cell death and inflammation in the muscles. This has been shown to be a promising strategy for treating polymyositis.

2 Mar 2022

Study finds booster shot did produce effective levels of neutralizing antibodies against omicron

A new study using serum from human blood samples suggests neutralizing antibody levels produced by two-dose mRNA vaccines against the original and early variants of the SARS-CoV-2 virus wane substantially over time, and offer essentially no protection against the omicron variant.

2 Mar 2022

People in England limited contact with others even outside of lockdown periods, suggests study

Transmission of respiratory viruses depends partly on the rate of close social contacts in a population. A study publishing March 1st in PLOS Medicine by Amy Gimma at the London School of Hygiene and Tropical Medicine, United Kingdom, and colleagues suggests that during the most restrictive period of lockdown in the United Kingdom, the number of reported contacts decreased by 75% from pre-pandemic levels.

2 Mar 2022

Phase 2/3 study of oral RHB-107 in non-hospitalized COVID-19 patients shows promising results

RedHill Biopharma Ltd., a specialty biopharmaceutical company, today announced positive top-line results from the Phase 2 part of the Phase 2/3 study of once-daily oral RHB-107 (upamostat) in non-hospitalized symptomatic COVID-19 patients, predominantly conducted in the U.S. (60/61 patients) as well as South Africa.

1 Mar 2022

Infectious Diseases News and Research

WVU researchers use machine learning and GIS to predict where COVID-19 testing will be most crucial

Single dose of new drug nirsevimab provides safe protection against RSV in healthy infants

IPD pooled analysis quantifies the underlying hematological response following malaria infection

Increasing trend of antimicrobial resistance in Eastern Mediterranean Region of World Health Organization

Mathematical model for evaluating factors driving SARS-CoV-2 transmission and pathogenesis

Study suggests recent common cold may actually lead to worse COVID-19 disease

Thermostable next-generation vaccine candidate against SARS-CoV-2 variants of concern studied in mice

Study to examine the risks for brain disorders from repetitive head impacts in contact sports

The relative dynamics of infection with the Delta and Omicron SARS-CoV-2 variants in aged and young Syrian hamsters

Microneedle treatments could significantly desensitize people with food allergies

Over a third vaccinated-but-unboosted adults have reservations about vaccinating children

Study shows the impact of COVID-19 restrictions on dengue cases in 2020

First dose SARS-CoV-2 vaccination coverage among younger children in America

Study explores coronavirus surveillance in bats from Argentina

Some oral bacteria associated with development of high blood pressure in postmenopausal women

Researchers reveal unique signature of genes expressed by hematopoietic stem cells

Targeting necroptosis using a necroptosis inhibitor lessens myositis-induced muscle weakness

Study finds booster shot did produce effective levels of neutralizing antibodies against omicron

People in England limited contact with others even outside of lockdown periods, suggests study

Phase 2/3 study of oral RHB-107 in non-hospitalized COVID-19 patients shows promising results

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