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Researchers report new signaling exchange that mediates normal mammary gland development

The human body develops most tissue types during fetal development, in a mother's uterus. Yet one only tissue develops after birth: the mammary gland.

18 May 2018

Researchers discover mutation that can protect against Alzheimer's disease in mice

Researchers at the RIKEN Center for Brain Science have discovered a mutation that can protect against Alzheimer's disease in mice. Published in the scientific journal Nature Communications, the study found that a specific mutation can reduce the characteristic accumulation of the amyloid-beta peptide that occurs.

16 May 2018

Researchers use body odor to diagnose malaria

An international team of researchers recently discovered that malaria could be diagnosed through changes in body odor.

15 May 2018

New study to explore link between diet, intestinal microbiota and cognitive decline

Are abnormal intestinal microorganisms a risk factor for developing cognitive impairment? Researchers at Rush University Medical Center are trying to answer that question with a new study that will explore how the intestinal microbiota – the bacteria in the intestine –influence the progression of cognitive decline and the development of Alzheimer's disease.

14 May 2018

Enhancing the effects of vitamin D to curb type 2 diabetes

More than 27 million people in the United States are living with type 2 diabetes, according to the Centers for Disease Control and Prevention. As the population ages and a growing percentage of people become overweight or obese, that number is expected to increase.

10 May 2018

Researchers manipulate bacterial species in the gut using diet

Scientists from Stanford University School of Medicine have shown that by manipulating diet in a mouse model, it is possible to favor the engraftment of a specific bacterial strain over others.

10 May 2018

Johns Hopkins researchers identify protein clumps in diseased hearts

Similar to how protein clumps build up in the brain in people with some neurodegenerative diseases such as Alzheimer's and Parkinson's diseases, protein clumps appear to accumulate in the diseased hearts of mice and people with heart failure, according to a team led by Johns Hopkins University researchers.

9 May 2018

Study finds new molecular mechanism for neurodegeneration in frontotemporal dementia

A new study in Biological Psychiatry reports that dementia-related and psychiatric-related proteins cluster together to form aggregates in the brain, leading to abnormal cell function and behavior.

8 May 2018

Nuclear pore complexes are critical for survival of circulating T cells, study shows

Nuclear pore complexes in the nuclear membrane not only control the transport of molecules into and out of the nucleus- they play an essential role in the survival of T cells.

8 May 2018

New eye drop may be potentially effective in treating seasonal eye allergies

A recent study shows that a new eye drop may be a potentially effective treatment for seasonal eye allergies, a condition affecting millions of people worldwide.

4 May 2018

Novel PET tracer could provide early detection of rheumatoid arthritis

A novel PET tracer developed by Korean researchers can visualize joint inflammation and could provide early diagnosis of rheumatoid arthritis, a common autoimmune disease that causes chronic inflammation of joints and can lead to deformity and dysfunction.

3 May 2018

Therapeutic RNA corrects error in genetic processing that leads to familial dysautonomia

Scientists at Cold Spring Harbor Laboratory have identified a therapeutic RNA molecule that corrects the error in genetic processing that leads to familial dysautonomia, a rare inherited neurodegenerative disorder.

30 Apr 2018

Gene therapy is the best stratagem to impact the course of GM2 gangliosidosis

Since its clinical description in 1881, Tay-Sachs disease has had almost totemic significance as a cruel and relentless genetic condition that destroys the developing brain of babies and young children.

28 Apr 2018

Researchers uncover the mystery of B cell receptors

When a pathogen evades or overcomes our innate immune defenses, the adaptive immune system kicks into action. There are two types of adaptive immune responses: cell-mediated immunity mediated by T cells and humoral immunity mediated by antibodies produced by B cells.

27 Apr 2018

Scientists discover potential therapeutic target for devastating premature aging disease

Scientists from the University of Cambridge have identified a potential therapeutic target in the devastating genetic disease Hutchinson-Gilford Progeria Syndrome (HGPS), which is characterized by premature aging.

27 Apr 2018

New noninvasive technique uses blood test to detect brain tumor biomarkers

Taking a biopsy of a brain tumor is a complicated and invasive surgical process, but a team of researchers at Washington University in St. Louis is developing a way that allows them to detect tumor biomarkers through a simple blood test.

26 Apr 2018

Researchers uncover how obesity leads to cancer in epithelial cells

A new study led by researchers at Hokkaido University has shown that obesity may enhance the progression of cancer, while aspirin may protect against it.

26 Apr 2018

Researchers target telomerase for killing NRAS-mutant melanoma cells

Targeting telomerase was effective at killing NRAS-mutant melanoma cells, and the impact was further enhanced when the strategy was paired with an inhibitor of mitochondrial function, according to study results by The Wistar Institute published in Oncogene.

26 Apr 2018

MU researchers use new techniques to fight against diabetic retinopathy

Diabetic retinopathy is a retinal microvascular disease that often causes blindness in adults who have had diabetes mellitus for 10 years or more. Estimates are that 600 million people will have some sort of diabetic retinopathy by 2040.

25 Apr 2018

Scientists clarify casual role of oxidative stress in metabolically abnormal and healthy obesities

Scientists at Osaka University clarified that deletion of adipose oxidative stress (Fat ROS) decreased lipid accumulation in the liver, clinically improving insulin resistance and inducing metabolically healthy obesity.

25 Apr 2018

Mouse Model News and Research

Researchers report new signaling exchange that mediates normal mammary gland development

Researchers discover mutation that can protect against Alzheimer's disease in mice

Researchers use body odor to diagnose malaria

New study to explore link between diet, intestinal microbiota and cognitive decline

Enhancing the effects of vitamin D to curb type 2 diabetes

Researchers manipulate bacterial species in the gut using diet

Johns Hopkins researchers identify protein clumps in diseased hearts

Study finds new molecular mechanism for neurodegeneration in frontotemporal dementia

Nuclear pore complexes are critical for survival of circulating T cells, study shows

New eye drop may be potentially effective in treating seasonal eye allergies

Novel PET tracer could provide early detection of rheumatoid arthritis

Therapeutic RNA corrects error in genetic processing that leads to familial dysautonomia

Gene therapy is the best stratagem to impact the course of GM2 gangliosidosis

Researchers uncover the mystery of B cell receptors

Scientists discover potential therapeutic target for devastating premature aging disease

New noninvasive technique uses blood test to detect brain tumor biomarkers

Researchers uncover how obesity leads to cancer in epithelial cells

Researchers target telomerase for killing NRAS-mutant melanoma cells

MU researchers use new techniques to fight against diabetic retinopathy

Scientists clarify casual role of oxidative stress in metabolically abnormal and healthy obesities

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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