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Penn’s immunotherapy receives FDA's Breakthrough Therapy designation for ALL treatment

A University of Pennsylvania-developed personalized immunotherapy has been awarded the U.S. Food and Drug Administration's Breakthrough Therapy designation for the treatment of relapsed and refractory adult and pediatric acute lymphoblastic leukemia (ALL).

7 Jul 2014

Cheaper drug could potentially improve heart attack patient outcomes and save health services millions

A new study published in The Lancet compares outcomes for two drugs used to prevent blood clot formation during emergency heart attack treatment. The study suggests that use of one of the drugs, heparin, could result in improved outcomes (such as a reduced rate of repeat heart attacks), compared to the other drug tested, bivalirudin, which is in widespread use in high-income countries, and is around 400 times more expensive than heparin.

7 Jul 2014

AutoGenomics, Genomas sign agreement to develop DNA-guided diagnostic systems

AutoGenomics, Inc, a leader in automated microarray technology for molecular diagnostics, and Genomas, a biomedical company enabling DNA-guided medicine for personal healthcare, announced today that they have signed an agreement to jointly develop genetic tests and DNA-guided diagnostic systems for optimal selection of statins and for improved delivery of statin therapy for the treatment of cardiovascular disease, obesity and diabetes.

7 Jul 2014

Treating ulcerative colitis and Crohn’s disease

Ulcerative colitis and Crohn’s disease are idiopathic (we don’t know the cause) inflammatory diseases (IBD) of the colon and/or small bowel. They are chronic in that we do not have a medical cure and are differentiated from IBS (irritable bowel syndrome) by inflammation that causes ulcerations of the GI tract.

7 Jul 2014

Study analyzes effects of antidepressant drugs on well-being in children and adolescents

In an article published in the current issue of Psychotherapy and Psychosomatics the effects of antidepressant drugs on well-being in children and adolescents are analyze.

7 Jul 2014

Scientists develop chip for detection of RNA strand of dengue fever virus

Scientists at the Center for Research and Advanced Studies (Cinvestav) in Mexico developed a chip (also known as cDNA microarray) that allows detection of the RNA strand of the dengue fever virus.

7 Jul 2014

Hospira acquires API manufacturing and R&D facilities from Orchid for about $218 million

Hospira, Inc., the world's leading provider of injectable drugs and infusion technologies, today announced it has completed the acquisition of an active pharmaceutical ingredient (API) manufacturing facility and an associated research and development (R&D) facility from Orchid Chemicals & Pharmaceuticals Ltd., a leading Indian pharmaceuticals company, for approximately $218 million, after settling prior advances of approximately $30 million.

7 Jul 2014

Standard risk factors stratify already high-risk diabetic patients

Cardiovascular disease risk factors are associated with mortality even among patients with Type 2 diabetes who are already at high risk due to having high coronary artery calcified plaque, say researchers.

4 Jul 2014

OHSU professor recognized with AAAS Martin and Rose Wachtel Cancer Research Award

Jeffrey Tyner, Ph.D., assistant professor of Cell, Developmental & Cancer Biology for Oregon Health & Science University (OHSU) and a researcher with OHSU's Knight Cancer Institute, has won a distinguished award from the American Association for the Advancement of Science (AAAS) for the development of a research program that more rapidly identifies the mutations driving a patient's cancer and accelerates development of precision treatments.

4 Jul 2014

MEF2 gene: A potential therapeutic target to protect neuronal loss in Alzheimer's, Parkinson's

A new study by researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) has identified a chemical "switch" that controls both the generation of new neurons from neural stem cells and the survival of existing nerve cells in the brain.

4 Jul 2014

Transcription factor IRF4 plays key role in brown fat's thermogenic process

The body contains two types of fat cells, easily distinguished by color: White and brown. While white fat serves to store excess calories until they're needed by the body, brown adipocytes actually burn fat by turning it into heat.

4 Jul 2014

Researchers discover mechanical threshold that regulates angiogenesis

Angiogenesis, the sprouting of new blood vessels from pre-existing ones, is essential to the body's development. As organs grow, vascular networks must grow with them to feed new cells and remove their waste.

4 Jul 2014

Study shows how psychedelic drug alters brain activity to produce unusual psychological effects

New research shows that our brain displays a similar pattern of activity during dreams as it does during a mind-expanding drug trip.

4 Jul 2014

State highlights: N.C. lawmakers reach Medicaid agreement; Idaho asks SCOTUS to take up Medicaid reimbursement

For the past few weeks, two big issues have kept the two chambers of the General Assembly from reaching an agreement on next year's state budget: teacher salaries and Medicaid. But on Wednesday, the Senate and the House of Representatives finally moved closer to agreement on their Medicaid forecasts, loosening a logjam that's kept legislators in Raleigh past July 1, the beginning of the fiscal year (Hoban, 7/3).

4 Jul 2014

Metal-free chemical reaction for anti-HIV, anti-cancer and anti-bacterial drugs

A team of researchers from KU Leuven, in Belgium, has developed an economical, reliable and heavy metal-free chemical reaction that yields fully functional 1,2,3-triazoles. Triazoles are chemical compounds that can be used as building blocks for more complex chemical compounds, including pharmaceutical drugs.

4 Jul 2014

Discovery points the way to potential new strategies to treat blood disorders

Like a line of falling dominos, a cascade of molecular events in the bone marrow produces high levels of inflammation that disrupt normal blood formation and lead to potentially deadly disorders including leukemia, an Indiana University-led research team has reported.

4 Jul 2014

Acute kidney injury and chronic kidney disease are interconnected, say GW researchers

For more than 40 years, physicians have treated diminished kidney function as two distinct syndromes: acute kidney injury (AKI) and chronic kidney disease (CKD). However, recent epidemiologic and mechanistic studies suggest the two syndromes are not distinct entities, but interconnected.

4 Jul 2014

Two life-threatening adverse drug reactions that affect the skin likely to recur

Individuals who are hospitalized for the skin conditions of Stevens-Johnson syndrome and toxic epidermal necrolysis appear to have a high risk of recurrence, according to a study in the June 4 issue of JAMA.

4 Jul 2014

Researchers discover new way by which metabolism is linked to regulation of DNA

A research team at the Faculty of Medicine & Dentistry at the University of Alberta have discovered a new way by which metabolism is linked to the regulation of DNA, the basis of our genetic code. The findings may have important implications for the understanding of many common diseases, including cancer.

4 Jul 2014

Scientists produce drug compound with potential to block HIV transmission in women

Scientists at the University of Nebraska-Lincoln College of Engineering's Biological Process Development Facility have successfully produced a drug compound with potential to block HIV transmission in women.

4 Jul 2014

Drugs News and Research

Penn’s immunotherapy receives FDA's Breakthrough Therapy designation for ALL treatment

Cheaper drug could potentially improve heart attack patient outcomes and save health services millions

AutoGenomics, Genomas sign agreement to develop DNA-guided diagnostic systems

Treating ulcerative colitis and Crohn’s disease

Study analyzes effects of antidepressant drugs on well-being in children and adolescents

Scientists develop chip for detection of RNA strand of dengue fever virus

Hospira acquires API manufacturing and R&D facilities from Orchid for about $218 million

Standard risk factors stratify already high-risk diabetic patients

OHSU professor recognized with AAAS Martin and Rose Wachtel Cancer Research Award

MEF2 gene: A potential therapeutic target to protect neuronal loss in Alzheimer's, Parkinson's

Transcription factor IRF4 plays key role in brown fat's thermogenic process

Researchers discover mechanical threshold that regulates angiogenesis

Study shows how psychedelic drug alters brain activity to produce unusual psychological effects

State highlights: N.C. lawmakers reach Medicaid agreement; Idaho asks SCOTUS to take up Medicaid reimbursement

Metal-free chemical reaction for anti-HIV, anti-cancer and anti-bacterial drugs

Discovery points the way to potential new strategies to treat blood disorders

Acute kidney injury and chronic kidney disease are interconnected, say GW researchers

Two life-threatening adverse drug reactions that affect the skin likely to recur

Researchers discover new way by which metabolism is linked to regulation of DNA

Scientists produce drug compound with potential to block HIV transmission in women

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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