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Genetic basis of uterine fibroids uncovered

A mutation located near the fatty acid synthase gene is associated with an increased predisposition for uterine leiomyomata or fibroids, suggest US study findings.

8 Oct 2012

Researchers discover smallest and fastest-known RNA switches

A University of Michigan biophysical chemist and his colleagues have discovered the smallest and fastest-known molecular switches made of RNA, the chemical cousin of DNA. The researchers say these rare, fleeting structures are prime targets for the development of new antiviral and antibiotic drugs.

8 Oct 2012

Researchers discover 8 new loci associated with susceptibility to atopic dermatitis

Researchers at the RIKEN Center for Genomic Medicine (CGM) and their colleagues have identified 8 new loci associated with susceptibility to atopic dermatitis in the Japanese population.

8 Oct 2012

Researchers decipher how AP-1 gene regulator controls survival of liver tumor-initiating cells

Researchers headed by Erwin Wagner, the Director of the BBVA Foundation-CNIO Cancer Cell Biology Programme at the Spanish National Cancer Research Centre (CNIO), have deciphered how a stress-inducible gene regulator, AP-1, controls the survival of liver tumor-initiating cells. These results, published in the online edition of Nature Cell Biology, could provide new preventive strategies and identify potentially targetable molecules to prevent liver cancer.

8 Oct 2012

Kaneka to launch new Protein A Chromatography Resin for purification of therapeutic antibodies

Kaneka Corporation on 19/09/2012, announces the launch of KANEKA KanCapA, a new Protein A Chromatography Resin for the purification of therapeutic antibodies.

8 Oct 2012

FDA clears Fenwal's new plasma products

Fenwal Inc., a global leader specializing in separation technologies for blood and cell collection and therapy, announced today it has received clearance from the U.S. Food and Drug Administration for two new indications for collection of plasma products on the Fenwal Alyx and Amicus systems.

8 Oct 2012

Translational Genomics Research Institute creates new center for rare childhood disorders

The Translational Genomics Research Institute (TGen) today announced the creation of a new center that could have life changing effects on the lives of potentially thousands of children and their families.

6 Oct 2012

Researchers identify mechanism that protects from developing uncontrollable fear

Researchers from the University of Exeter Medical School have for the first time identified the mechanism that protects us from developing uncontrollable fear.

6 Oct 2012

Study demonstrates efficacy of genotyping technology in identifying source of clinic infection outbreak

Researchers from East Carolina University used a new technique of genotyping to identify the source of a hematology clinic outbreak of Mycobacterium mucogenicum, a gram-positive, acid-fast bacteria found in tap water. This is the first outbreak of M. mucogenicum in an ambulatory care setting; five other outbreaks have been reported in hospital settings since 1995.

6 Oct 2012

BUSM leads genome-wide evaluation of genetic variants associated with Parkinson's disease

Boston University School of Medicine investigators have led the first genome-wide evaluation of genetic variants associated with Parkinson's disease (PD). The study, which is published online in PLOS ONE, points to the involvement of specific genes and alterations in their expression as influencing the risk for developing PD.

6 Oct 2012

Perplexing evolutionary history of malaria transmitting mosquito species

An African mosquito species with a deadly capacity to transmit malaria has a perplexing evolutionary history, according to discovery by researchers at the Fralin Life Science Institute at Virginia Tech.

6 Oct 2012

Progress toward preventing initial and recurrent episodes of C. diff infection

Surgeons are making progress toward preventing initial and recurrent episodes of clostridium difficile colitis (C. difficile or C. diff), a vicious bacterial infection that is estimated to affect about 336,000 people each year, typically patients on antibiotics.

6 Oct 2012

GRID1 thalamo-cortical gene variations absent in schizophrenia

Genetic variation in the glutamate receptor delta 1 gene affects gray matter of the anterior thalamus and left lateral prefrontal cortex in healthy individuals but not among patients with schizophrenia, suggest findings published in the Journal of Psychiatric Research.

5 Oct 2012

Article explores safety and efficacy of aerosol delivery of drugs in ICU patients

Essential medications can be delivered as inhaled drugs to critically ill patients in the Intensive Care Unit (ICU) who require mechanical ventilation to breathe. Aerosol drug delivery is highly complex, however, and if not done properly the medication will not reach the lungs and therapy will be ineffective.

5 Oct 2012

Researchers identify genetic risk allele for uterine fibroids

Uterine fibroids are the most common type of pelvic tumors in women and are the leading cause of hysterectomy in the United States. Researchers from Brigham and Women's Hospital (BWH) are the first to discover a genetic risk allele (an alternative form of a gene) for uterine fibroids in white women using an unbiased, genome-wide approach.

5 Oct 2012

Study links PI3Kgamma molecule with multiple sclerosis

A University of Adelaide researcher has published results that suggest a possible new mechanism to control multiple sclerosis (MS).

5 Oct 2012

Newborn mice use mum's unique odour to begin breastfeeding

Researchers show for the first time that a mammal begins to suckle its mother's milk through a learned response built on learning her unique combination of smells. When it is born, the newborn is exposed to the smell of its mother's amniotic fluid and the baby then responds to those smells to feed.

5 Oct 2012

New prototype mouse model duplicates the human response in rheumatoid arthritis

Researchers at Northwestern University Feinberg School of Medicine have developed the first animal model that duplicates the human response in rheumatoid arthritis (RA), an important step that may enable scientists to discover better medicines to treat the disease.

5 Oct 2012

Vulnerability to ‘thin ideal’ may be genetic

Results from a study carried out in identical and nonidentical twins suggests that a woman’s risk for thin-ideal internalization may be genetic.

4 Oct 2012

Ketamine can help improve brain function in Rett syndrome mice

A promising study out today in the prestigious Journal of Neurosciences showed that in a mouse model of Rett syndrome, researchers were able to reverse abnormalities in brain activity and improve neurological function by treating the animals with an FDA-approved anesthesia drug, ketamine.

4 Oct 2012

Genetic News and Research

Genetic basis of uterine fibroids uncovered

Researchers discover smallest and fastest-known RNA switches

Researchers discover 8 new loci associated with susceptibility to atopic dermatitis

Researchers decipher how AP-1 gene regulator controls survival of liver tumor-initiating cells

Kaneka to launch new Protein A Chromatography Resin for purification of therapeutic antibodies

FDA clears Fenwal's new plasma products

Translational Genomics Research Institute creates new center for rare childhood disorders

Researchers identify mechanism that protects from developing uncontrollable fear

Study demonstrates efficacy of genotyping technology in identifying source of clinic infection outbreak

BUSM leads genome-wide evaluation of genetic variants associated with Parkinson's disease

Perplexing evolutionary history of malaria transmitting mosquito species

Progress toward preventing initial and recurrent episodes of C. diff infection

GRID1 thalamo-cortical gene variations absent in schizophrenia

Article explores safety and efficacy of aerosol delivery of drugs in ICU patients

Researchers identify genetic risk allele for uterine fibroids

Study links PI3Kgamma molecule with multiple sclerosis

Newborn mice use mum's unique odour to begin breastfeeding

New prototype mouse model duplicates the human response in rheumatoid arthritis

Vulnerability to ‘thin ideal’ may be genetic

Ketamine can help improve brain function in Rett syndrome mice

eBook: Using iPSCs models for human disease research and drug discovery eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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