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Computer analysis of family photos could help diagnose rare genetic disorders

Computer analysis of photographs could help doctors diagnose which condition a child with a rare genetic disorder has, say Oxford University researchers.

24 Jun 2014

Microparticles in crab, shrimp and lobster shells may help prevent inflammatory bowel disease

Yoshimi Shibata, Ph.D., professor of biomedical science in the Charles E. Schmidt College of Medicine at Florida Atlantic University, has received a $380,552 grant from the National Institute of Complementary and Alternative Medicine of the National Institutes of Health to further investigate how microparticles called "chitin" found in crab, shrimp and lobster shells have anti-inflammatory mechanisms that could lead to the development of novel preventive and therapeutic strategies for individuals who suffer from inflammatory bowel disease (IBD) and others diseases.

24 Jun 2014

Ligand Pharmaceuticals, TG Therapeutics sign global license agreement for IRAK-4 inhibitors

Ligand Pharmaceuticals Incorporated announced the signing of an exclusive global license agreement with TG Therapeutics, Inc. for the development and commercialization of Ligand's Interleukin-1 Receptor Associated Kinase-4 (IRAK-4) inhibitors.

24 Jun 2014

Mersana and Merck KGaA develop next-generation antibody-drug conjugates

Mersana Therapeutics, Inc., and the biopharmaceutical division of Merck KGaA, Darmstadt, Germany, which operates as EMD Serono in the United States and Canada, announced today an agreement to collaboratively develop next-generation antibody-drug conjugates (ADCs).

24 Jun 2014

State highlights: Ohio managed care plans launch; Bluecross Blueshield plan faces Ore. lawsuit; N.Y. policy on unvaccinated children upheld

A selection of health policy stories from Ohio, Oregon, New York, Colorado, Iowa, New Jersey, North Carolina, Georgia, California and Minnesota.

24 Jun 2014

Scientists turn to old class of antibiotics to fight superbugs resistant to modern medicine

Scientists at the University at Buffalo are turning to an old class of antibiotics to fight new superbugs resistant to modern medicine.

24 Jun 2014

Obese Americans report far greater overall satisfaction with weight loss surgery, medications

Obese and overweight Americans who have tried losing weight report far greater overall satisfaction with weight loss surgery and prescription weight loss medications than with diet, exercise and other self-modification methods, an Internet survey finds.

24 Jun 2014

Clusters of protein linked to cancer warp cell membranes

Supercomputer simulations have shown that clusters of a protein linked to cancer warp cell membranes, according to scientists at The University of Texas Health Science Center at Houston (UTHealth) Medical School.

24 Jun 2014

Education campaign fails to improve guideline adherence in paediatric AOM

Swedish researchers report that overall adherence to treatment guidelines for acute otitis media in children is good, at 70–90%, but that adherence to watchful waiting is poor.

23 Jun 2014

Study on digestion of milk could lead to development of new formulas for premature babies

A new study on the digestion of milk could lead to the development of new formulas for premature babies, weight loss drinks and potentially new drug delivery systems.

23 Jun 2014

Study paves way to develop novel therapies for nasopharyngeal cancer

A team of scientists from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore, National University Cancer Institute Singapore (NCIS) and National University Hospital Singapore (NUH), discovered a distinct mutational signature and nine significantly mutated genes associated with nasopharyngeal cancer, paving the way to developing novel therapies for this deadly disease.

23 Jun 2014

Study explores new ways to improve medications to treat type 2 diabetes

A better understanding of how the transcription factor Peroxisome Proliferator-Activated Receptor Gamma (PPARgamma) works is critical to find new ways to improve medications to treat type 2 diabetes.

23 Jun 2014

Italian Medicines Agency grants marketing authorization to ILUVIEN for chronic DME treatment

pSivida Corp., a leader in the development of sustained release, drug delivery products for treating eye diseases, today announced that the Italian Medicines Agency (Agenzia Italiana del Farmaco) has granted marketing authorization to ILUVIEN for the treatment of vision impairment associated with chronic diabetic macular edema (DME) considered insufficiently responsive to available therapies.

23 Jun 2014

Private insurers clamp down on drug prices

More health plans are refusing to cover certain brand-name drugs unless drugmakers offer discounts for them, reports The New York Times.

23 Jun 2014

XenoPort initiates XP23829 Phase 2 clinical trial in patients with psoriasis

XenoPort, Inc. announced today that it has initiated a Phase 2 clinical trial of XP23829, its proprietary investigational next-generation fumaric acid product candidate. The trial is a multi-center, randomized, double-blind, placebo-controlled study designed to assess the efficacy and safety of XP23829 as a potential treatment of patients with moderate-to-severe chronic plaque-type psoriasis.

23 Jun 2014

Treatment with diabetes drug liraglutide improves cardiovascular risk factors

Treatment with the diabetes drug liraglutide, in combination with diet and exercise, led to a significant reduction in weight and improved a number of cardiovascular risk factors, including high blood pressure and high cholesterol, according to a multicenter study.

23 Jun 2014

BPA appears to increase proliferation of breast cancer cells, diminish effectiveness of treatments

Bisphenol A (BPA), a chemical commonly used in plastics, appears to increase the proliferation of breast cancer cells, according to Duke Medicine researchers presenting at an annual meeting of endocrine scientists.

23 Jun 2014

Aradigm begins Pulmaquin Phase III study for treatment of non-CF BE

Aradigm Corporation ("Aradigm" or the "Company") today announced the dosing of the first patient in the ORBIT-4 (Once-daily Respiratory Bronchiectasis Inhalation Treatment) Phase III pivotal clinical trial of Aradigm's proprietary formulation of inhaled ciprofloxacin (Pulmaquin®) for the treatment of non-cystic fibrosis bronchiectasis (non-CF BE).

23 Jun 2014

BioLineRx announces in-licensing of BL-1110 compound for treatment of neuropathic pain

BioLineRx Ltd., a clinical-stage biopharmaceutical company dedicated to identifying, in-licensing and developing promising therapeutic candidates, announced today it has in-licensed BL-1110, a novel compound for the treatment of neuropathic pain.

23 Jun 2014

First Edition: June 23, 2014

Today's early morning highlights from the major news organizations, including news stories about healthcare.gov management changes.

23 Jun 2014

Drugs News and Research

Computer analysis of family photos could help diagnose rare genetic disorders

Microparticles in crab, shrimp and lobster shells may help prevent inflammatory bowel disease

Ligand Pharmaceuticals, TG Therapeutics sign global license agreement for IRAK-4 inhibitors

Mersana and Merck KGaA develop next-generation antibody-drug conjugates

State highlights: Ohio managed care plans launch; Bluecross Blueshield plan faces Ore. lawsuit; N.Y. policy on unvaccinated children upheld

Scientists turn to old class of antibiotics to fight superbugs resistant to modern medicine

Obese Americans report far greater overall satisfaction with weight loss surgery, medications

Clusters of protein linked to cancer warp cell membranes

Education campaign fails to improve guideline adherence in paediatric AOM

Study on digestion of milk could lead to development of new formulas for premature babies

Study paves way to develop novel therapies for nasopharyngeal cancer

Study explores new ways to improve medications to treat type 2 diabetes

Italian Medicines Agency grants marketing authorization to ILUVIEN for chronic DME treatment

Private insurers clamp down on drug prices

XenoPort initiates XP23829 Phase 2 clinical trial in patients with psoriasis

Treatment with diabetes drug liraglutide improves cardiovascular risk factors

BPA appears to increase proliferation of breast cancer cells, diminish effectiveness of treatments

Aradigm begins Pulmaquin Phase III study for treatment of non-CF BE

BioLineRx announces in-licensing of BL-1110 compound for treatment of neuropathic pain

First Edition: June 23, 2014

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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