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Mapping neuronal IL-1R1 expression reveals insights into brain function

Interleukin-1 (IL-1) is a key molecule involved in inflammation and plays an important role in both healthy and diseased states.

17 Jan 2025

Breakthrough reveals how DNA and RNA epigenetics work together to control genes

Our genes contain all the instructions our body needs to function, but their expression must be finely regulated to guarantee that each cell performs its role optimally.

17 Jan 2025

New rabbit model provides insights into CF-related pancreatic endocrine pathology

Cystic fibrosis (CF) is a life-threatening genetic disease affecting multiple organ systems, with pancreatic dysfunction representing a critical and often overlooked complication.

17 Jan 2025

Researchers investigate myocarditis in preschoolers caused by parvovirus B19 outbreak

Researchers document the harmful consequences of myocarditis in preschool students, caused by a regional outbreak of parvovirus B19 in northern Greece.

17 Jan 2025

New probes offer insight into cholesterol's role in Alzheimer's disease

The search for answers to Alzheimer's disease and other neurodegenerative disorders remains one of the most pressing goals in brain research. Maciej J. Stawikowski, Ph.D., an assistant professor of chemistry and biochemistry at Florida Atlantic University's Charles E. Schmidt College of Science, believes the key may lie in understanding how cholesterol and other lipids move through cells and affect their communication.

17 Jan 2025

New clinical trial aims to extend survival for bile duct cancer patients

A new clinical trial, sponsored by UCL and UCLH, aims to extend survival for some patients with cancer in the biliary tract by treating them with therapies specifically tailored to the genetic profile of their tumor.

17 Jan 2025

NIMH awards $1.5 million grant for long COVID neurological research

The National Institute of Mental Health has awarded a significant grant of $1.5 million to Jianyang Du, PhD, of the University of Tennessee Health Science Center, for a research study aimed at uncovering the cellular and molecular mechanisms that lead to neurological disorders caused by long COVID-19.

16 Jan 2025

Protein CD74 could predict immunotherapy response in bowel cancer

Researchers at the Francis Crick Institute and Barts Cancer Institute, Queen Mary University of London, have shown that the amount of a protein called CD74 can indicate which people with bowel cancer may respond best to immunotherapy.

16 Jan 2025

Researchers discover a major driver of osteosarcoma

A major driver of the bone cancer osteosarcoma has been discovered by researchers from UCL, EMBL EBI and the Royal National Orthopaedic Hospital, providing insights that could help to predict cancer severity and how patients will respond to treatment.

16 Jan 2025

AstraZeneca's Pioneering Research in Heart Failure and ATTR-CM

Mina Makar highlights AstraZeneca's commitment to advancing heart failure research and innovative therapies, addressing critical needs in cardiovascular health.

16 Jan 2025

Pittcon to make historic first appearance in Boston’s world-leading scientific hub

Pittcon 2025 in Boston: a landmark event uniting industry and academia to advance analytical chemistry and foster groundbreaking scientific collaboration.

From Pittcon 16 Jan 2025

Targeting tertiary lymphoid structures for cancer treatment

A research team at Memorial Sloan Kettering Cancer Center (MSK) has made new insights into how the body forms immune cell clusters called tertiary lymphoid structures (TLSs) in response to foreign threats such as cancer.

16 Jan 2025

Mouse protein disrupts cancer-causing epigenetic changes in human colorectal cancer

A little-known mouse protein disrupts cancer-causing chemical changes to genes associated with human colorectal cancer cells and potentially could be used to treat solid tumors, according to a new study from researchers at the Johns Hopkins Kimmel Cancer Center and the Chinese Academy of Sciences.

16 Jan 2025

Tiny vesicles offer powerful new approach for cancer treatment

A new twist on a decades-old anticancer strategy has shown powerful effects against multiple cancer types in a preclinical study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

16 Jan 2025

Sapio Sciences introduces new tools for chemistry, molecular biology, GMP workflows, and immunogenicity

Sapio Sciences, the science-aware™ lab informatics platform, today announced the launch of Release 24.12, introducing new tools for chemistry, molecular biology, GMP workflows, and immunogenicity.

15 Jan 2025

New target identified for potential colorectal cancer treatment

Colorectal cancer (CRC) is a type of cancer that begins in the colon (large intestine) or rectum, which are parts of the digestive system.

15 Jan 2025

Scientists discover how specific protein regions contribute to breast cancer

Researchers at Case Western Reserve University School of Medicine have discovered how specific protein regions contribute to breast cancer.

15 Jan 2025

Semaglutide improves glycemic control with automated insulin delivery

Semaglutide combined with automated insulin delivery enhances glucose control in type 1 diabetes, lowering insulin requirements and aiding weight management.

15 Jan 2025

CN Bio signs strategic partnership with Primetech Corporation to establish distribution channel for OOC solutions in Japan

CN Bio, a leading provider of Organ-on-a-chip (OOC) systems and solutions that accelerate drug discovery and development workflows, today announced it has entered into a strategic partnership with Japanese life sciences research equipment distributor, Primetech.

From CN Bio 15 Jan 2025

Genetic risk factor linked to increased susceptibility to SARS-CoV-2 infection

Researchers have identified a novel genetic risk factor for SARS-CoV-2 infection, providing new insights into the virus' ability to invade human cells. SARS-CoV-2 is the virus that spreads COVID-19.

15 Jan 2025