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Submicroscopic particles could make MRI far more powerful tool to detect disease

Submicroscopic particles that contain even smaller particles of iron oxide could make magnetic resonance imaging (MRI) a far more powerful tool to detect and fight disease.

16 Jun 2014

States, insurance plans wrestle over decisions to offer costly hepatitis C drug

The medication, named Sovaldi, has shown great promise in fighting the deadly disease, but it is very expensive: The treatment regimen runs about $84,000 per patient.

16 Jun 2014

Canola bread diet experiences reduction in blood glucose levels and LDL cholesterol

Canola is Canada's oil and new research from St. Michael's Hospital suggests it should also be one of the oils of choice for people with Type 2 diabetes.

16 Jun 2014

Kids with rare mutations in two genes are 4 times more likely to develop severe scoliosis

Children with rare mutations in two genes are about four times more likely to develop severe scoliosis than their peers with normal versions of the genes, scientists have found.

16 Jun 2014

First Edition: June 13, 2014

Today's headlines include various updates on what Virginia lawmakers did in an attempt to resolve the state's budget impasse and Medicaid expansion debate.

13 Jun 2014

PD MED trial: Levodopa drug better for long-term treatment of newly diagnosed PD

For long-term treatment of newly diagnosed Parkinson’s disease (PD), the old drug levodopa provides better mobility and a higher quality of life than the two main alternatives, dopamine agonists (DA) and monoamine oxidase type B inhibitors (MAOBI), according to the largest-ever trial of PD treatment (PD MED), published in The Lancet.

13 Jun 2014

Specific enzyme helps protect good commensal bacteria from harmful effects of antibiotics

Researchers from Case Western Reserve University in Cleveland have discovered that populating the gastrointestinal (GI) tracts of mice with Bacteroides species producing a specific enzyme helps protect the good commensal bacteria from the harmful effects of antibiotics.

13 Jun 2014

Research finds food addicts lacking psychological inhibition

Women with weight problems were more impulsive than average in a food-related psychology test, a new research paper has shown.

13 Jun 2014

Study uncovers why statins increase diabetes risk

McMaster University researchers may have found a novel way to suppress the devastating side effect of statins, one of the worlds' most widely used drugs to lower cholesterol and prevent heart disease.

13 Jun 2014

Investigators isolate protein that is responsible for fungus' ability to cross blood-brain barrier

In a remarkable series of experiments on a fungus that causes cryptococcal meningitis, a deadly infection of the membranes that cover the spinal cord and brain, investigators at UC Davis have isolated a protein that appears to be responsible for the fungus' ability to cross from the bloodstream into the brain.

13 Jun 2014

BioAnalytix now fills critical gap in area of biologic drug development

Biologic drugs are highly complex, but they may be the answer to many medical illnesses and conditions that currently have no treatment available.

13 Jun 2014

Excessive abuse of alcohol causes structural damage at molecular level to the brain

Joint research between the University of the Basque Country (UPV/EHU) and the University of Nottingham has identified, for the first time, the structural damage caused at a molecular level to the brain by the chronic excessive abuse of alcohol.

13 Jun 2014

Scientists are now one step closer to pill against obesity

Obesity and diabetes are among the fastest growing health problems in the world, and the hunt is in for a pill that can fight the problem.

13 Jun 2014

Co-ops struggle to enroll people

Elsewhere, Oregon officials are planning on limiting access to a new, pricey hepatitis C drug to state health plan members. Also, UnitedHealthcare is considering entering Georgia's health care exchange next year.

13 Jun 2014

State highlights: Calif. jails face problems with inmates with mental illness; Conn. patients to get 'facility fee' notice

Supervisor Mark Ridley-Thomas said board members and their staffs were not privy to communications sent by the U.S. Justice Department to Sheriff's Department and county mental health officials regarding ongoing problems until September. That's when county officials received a letter announcing a federal civil-rights investigation of the jail system (Sewell, 6/10).

12 Jun 2014

BRI researchers use tetramer technology to find T cells that drive rheumatoid arthritis

Researchers at Benaroya Research Institute at Virginia Mason used cutting-edge tetramer technology developed at BRI to find the T cells that drive rheumatoid arthritis (RA). "By using tetramer technology, we were able to examine whether T cells in people with rheumatoid arthritis were increased in number or were unique in other ways," says BRI Associate Director Jane Buckner, MD, who led the study with BRI Tetramer Core Laboratory Manager Eddie James, PhD.

12 Jun 2014

Osteoarthritis patients treated with SoluMatrix meloxicam report greater pain relief

Iroko Pharmaceuticals, LLC, a global specialty pharmaceutical company dedicated to advancing the science of analgesia, today will present Phase 3 results that showed osteoarthritis (OA) patients treated with investigational SoluMatrix meloxicam 5 mg and 10 mg, a low dose nonsteroidal anti-inflammatory drug (NSAID), reported significantly greater pain relief compared with placebo.

12 Jun 2014

New path may lead to powerful adjunctive novel therapy for PTSD treatment

There are currently only two FDA-approved medications for the treatment of posttraumatic stress disorder (PTSD) in the United States. Both of these medications are serotonin uptake inhibitors. Despite the availability of these medications, many people diagnosed with PTSD remain symptomatic, highlighting the need for new medications for PTSD treatment.

12 Jun 2014

DNA methylation identified as potential anti-TNF response biomarker for RA

DNA methylation has been identified as a potential biomarker of response to etanercept and adalimumab in patients with rheumatoid arthritis (RA) according to preliminary results from one of the largest methylome-wide investigations of treatment response to anti-TNF therapies.

12 Jun 2014

Mass. to spend $20 million to combat opioid use

Governor Deval Patrick announced the plan Tuesday that will also team with five other New England states to upgrade treatment and expand coverage abuse of the drugs.

12 Jun 2014

Drugs News and Research

Submicroscopic particles could make MRI far more powerful tool to detect disease

States, insurance plans wrestle over decisions to offer costly hepatitis C drug

Canola bread diet experiences reduction in blood glucose levels and LDL cholesterol

Kids with rare mutations in two genes are 4 times more likely to develop severe scoliosis

First Edition: June 13, 2014

PD MED trial: Levodopa drug better for long-term treatment of newly diagnosed PD

Specific enzyme helps protect good commensal bacteria from harmful effects of antibiotics

Research finds food addicts lacking psychological inhibition

Study uncovers why statins increase diabetes risk

Investigators isolate protein that is responsible for fungus' ability to cross blood-brain barrier

BioAnalytix now fills critical gap in area of biologic drug development

Excessive abuse of alcohol causes structural damage at molecular level to the brain

Scientists are now one step closer to pill against obesity

Co-ops struggle to enroll people

State highlights: Calif. jails face problems with inmates with mental illness; Conn. patients to get 'facility fee' notice

BRI researchers use tetramer technology to find T cells that drive rheumatoid arthritis

Osteoarthritis patients treated with SoluMatrix meloxicam report greater pain relief

New path may lead to powerful adjunctive novel therapy for PTSD treatment

DNA methylation identified as potential anti-TNF response biomarker for RA

Mass. to spend $20 million to combat opioid use

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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