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Highlights: Calif. insurance commissioner battle; food stamps and Medicaid in Calif.; Mo. and experimental drug therapies

Incumbent Democrat Dave Jones held a strong lead in Tuesday's primary election voting for state insurance commissioner, but he still faces a rematch in November against Republican challenger Ted Gaines (Lifsher, 6/3).

5 Jun 2014

New single-dose antibiotic is as effective as twice-daily infusion given for up to 10 days

In the battle against stubborn skin infections, including methicillin-resistant Staphylococcus aureus (MRSA), a new single-dose antibiotic is as effective as a twice-daily infusion given for up to 10 days, according to a large study led by Duke Medicine researchers.

5 Jun 2014

Study reveals molecular mechanism of cell death

Researchers at VIB and Ghent University have unraveled the mechanism of necroptosis. This is a type of cell death that plays a crucial role in numerous diseases, from viral infections and loss of auditory nerve cells to multiple sclerosis, acute heart failure and organ transplantation.

5 Jun 2014

States scramble to pay hefty tab for health exchange fixes

According to The Wall Street Journal, five states -- Maryland, Massachusetts, Minnesota, Nevada and Oregon -- will look to their own funds, remaining federal grants and new federal funding requests to pay these costs.

5 Jun 2014

Discovery of IDE may lead to new treatment approaches for diabetes

The discovery of an inhibitor of the Insulin Degrading Enzyme (IDE), a protein responsible for the susceptibility of diabetes because it destroys insulin in the body, may lead to new treatment approaches for diabetes.

5 Jun 2014

Federal appeals court blocks Ariz. abortion pill restrictions

The court said the state didn't present evidence that the regulations furthered women's health. Elsewhere, a bill to stop employers from denying birth control coverage in their plans is considered in New York.

5 Jun 2014

NIH study finds that MDMA drug can be more dangerous in hot, crowded settings

A moderate dose of MDMA, commonly known as Ecstasy or Molly, that is typically nonfatal in cool, quiet environments can be lethal in rats exposed to conditions that mimic the hot, crowded, social settings where the drug is often used by people, a study finds.

5 Jun 2014

New antibiotic proves effective in treating serious bacterial skin and skin-structure infections

A study published in today's New England Journal of Medicine reports that the antibiotic dalbavancin is as effective as vancomycin, the current standard-of-care antibiotic used to treat serious bacterial skin and skin-structure infections.

5 Jun 2014

Citing patient danger, Minn. takes over nursing home

The state health department says it took over the Camden Care Center because of serious violations that endangered patients and a high number of regulatory violations.

5 Jun 2014

NORD's letter to FDA raises concerns on rare diseases

In a letter submitted today to the U.S. Food and Drug Administration (FDA), the National Organization for Rare Disorders (NORD) urged Commissioner Margaret Hamburg to give serious consideration to the concerns of the rare disease community when setting policy regarding official names for biologics, including biosimilars.

5 Jun 2014

High dose vitamin C therapy may have positive effect on Epstein-Barr virus infection

The Epstein-Barr virus (EBV) is a member of the herpes family that targets lymphocytes and epithelial cells. While the infection is usually benign, it can in some cases lead to acute infectious mononucleosis and can impair the immune system. EBV is also linked to several malignancies. There is currently no cure for removing EBV infections and very little success treating acute EBV infection and mononucleosis with drugs.

4 Jun 2014

Synthetic peptide carrier delivers drugs through blood-brain barrier for cancer treatment

Researchers at Mayo Clinic have demonstrated in a mouse model that their recently developed synthetic peptide carrier is a potential delivery vehicle for brain cancer chemotherapy drugs and other neurological medications. The findings appear in PLOS ONE.

4 Jun 2014

SYNERA can help prevent needle stick pain associated with superficial IVs

Galen US Incorporated today announced that the U.S. Food and Drug Administration (FDA) recently approved a labeling change that allows SYNERA® (lidocaine and tetracaine) topical patch to be used at home.

4 Jun 2014

First Edition: June 4, 2014

Today's headlines include a story about the costs some states will face in attempting to fix their online insurance marketplace.

4 Jun 2014

Scientists create 3-D silicon structures using water droplets

Researchers from the University of Twente in the Netherlands have taken the precise art of origami down to the microscopic scale.

4 Jun 2014

AFFiRiS releases positive study results of AD04 therapeutic drug in Alzheimer patients

AFFiRiS announced today the results of a phase II study in Alzheimer patients. AFFiRiS' proprietary compound AD04 is the first drug ever to demonstrate clinical and biomarker effects consistent with disease modification in Alzheimer patients.

4 Jun 2014

New nanomedicine allows glaucoma patients to do away with daily eye drops

Scientists from Nanyang Technological University (NTU) and the Singapore Eye Research Institute (SERI) have jointly developed a new nanomedicine that will allow glaucoma patients to do away with daily eye drops.

4 Jun 2014

Community OOPPs can improve bystander responses to overdose of heroin

Community opioid overdose prevention programs (OOPPs)-including the use of naloxone for rapid drug reversal-can improve bystander responses to overdose of heroin and related drugs, according to a review in the June Journal of Addiction Medicine, the official journal of the American Society of Addiction Medicine.

4 Jun 2014

Incyte’s ruxolitinib Phase III study for polycythemia vera achieves primary endpoint

Incyte Corporation (Nasdaq: INCY) today announced results from the RESPONSE trial, the first pivotal Phase III study evaluating a JAK1/JAK2 inhibitor for the treatment of polycythemia vera (PV).

4 Jun 2014

EC approves extension of INVEGA antipsychotic drug to include adolescents aged 15 years and older

Janssen-Cilag International NV announced today that the European Commission has approved an extension of the oral atypical antipsychotic INVEGA® (paliperidone ER) schizophrenia indication, to include adolescents aged 15 years and older.

4 Jun 2014

Drugs News and Research

Highlights: Calif. insurance commissioner battle; food stamps and Medicaid in Calif.; Mo. and experimental drug therapies

New single-dose antibiotic is as effective as twice-daily infusion given for up to 10 days

Study reveals molecular mechanism of cell death

States scramble to pay hefty tab for health exchange fixes

Discovery of IDE may lead to new treatment approaches for diabetes

Federal appeals court blocks Ariz. abortion pill restrictions

NIH study finds that MDMA drug can be more dangerous in hot, crowded settings

New antibiotic proves effective in treating serious bacterial skin and skin-structure infections

Citing patient danger, Minn. takes over nursing home

NORD's letter to FDA raises concerns on rare diseases

High dose vitamin C therapy may have positive effect on Epstein-Barr virus infection

Synthetic peptide carrier delivers drugs through blood-brain barrier for cancer treatment

SYNERA can help prevent needle stick pain associated with superficial IVs

First Edition: June 4, 2014

Scientists create 3-D silicon structures using water droplets

AFFiRiS releases positive study results of AD04 therapeutic drug in Alzheimer patients

New nanomedicine allows glaucoma patients to do away with daily eye drops

Community OOPPs can improve bystander responses to overdose of heroin

Incyte’s ruxolitinib Phase III study for polycythemia vera achieves primary endpoint

EC approves extension of INVEGA antipsychotic drug to include adolescents aged 15 years and older

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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