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$Big data can help assess risk prediction for osteoporosis, fractures$

Big data can help assess risk prediction for osteoporosis, fractures

Years of suffering and billions of euro in global health care costs, arising from osteoporosis-related bone fractures, could be eliminated using big data to target vulnerable patients, according to researchers at Lero, the Science Foundation Ireland Research Centre for Software.

15 Feb 2021

Study: Aspirin should be favored to prevent blood clots in children after complex heart surgery

Aspirin should be favored over warfarin to prevent blood clotting in children who undergo a surgery that replumbs their hearts, according to a new study.

14 Feb 2021

Study reveals mechanisms behind sensitivity of multiple myeloma cells to EZH2 inhibition

Researchers from Uppsala University show in a new study that inhibition of the protein EZH2 can reduce the growth of cancer cells in the blood cancer multiple myeloma.

13 Feb 2021

FDA approves drug to reduce frequency of chemotherapy-induced bone marrow suppression

Today, the U.S. Food and Drug Administration approved Cosela (trilaciclib) as the first therapy in its class to reduce the frequency of chemotherapy-induced bone marrow suppression in adults receiving certain types of chemotherapy for extensive-stage (when the cancer has spread beyond the lungs) small cell lung cancer.

13 Feb 2021

Scientists conduct interdisciplinary study on using nanoparticles to fight leukemia

Scientists from Scientific and Educational Center & Smart Materials and Biomedical Applications under the leadership of Kateryna Levada together with colleagues from Center for Immunology and Cellular Biotechnology of the Immanuel Kant Baltic Federal University conducted a joint interdisciplinary study on the development of a new method for treating leukemia using nanomaterials.

11 Feb 2021

STING activation may be a new approach to reduce graft-versus-host disease

MUSC Hollings Cancer Center researcher Yongxia Wu, Ph.D., identified a new target molecule in the fight against graft-versus-host disease (GVHD).

11 Feb 2021

Study offers a new way to treat children with bow hunter syndrome

Fusing the neck's top two vertebrae can prevent repeat strokes in children with bow hunter syndrome, a rare condition that affects a handful of U.S. pediatric patients each year, UT Southwestern researchers suggest in a recent study.

11 Feb 2021

Partial replacement of animal proteins with plant proteins increases bone formation in adults

In a study conducted at the University of Helsinki, Finland, 136 adults adhered to one of three study diets for 12 weeks. One of them corresponded to the average Finnish diet, containing roughly 70% animal-derived protein of total protein, while most of the plant-based protein originated from cereal products.

11 Feb 2021

Single strain of bacteria may reduce the severity of graft-versus-host disease

MUSC Hollings Cancer Center researchers found that a single strain of bacteria may be able to reduce the severity of graft-versus-host disease (GVHD), as reported online in February 2021 in JCI Insight.

11 Feb 2021

Study provides new insights into the mechanism of bone marrow tissue

Imagine a day when clinicians treating people with blood diseases such as leukemia or multiple myeloma can send in requests for laboratories to custom-produce specific types of blood cells to replace those affected by the disease.

10 Feb 2021

Nature Inspired Materials

An Interview with Dr. Lauren Zarzar, exploring how the natural world can serve as both inspiration and model for the invention of dynamic materials, to be presented at Pittcon 2021

From Pittcon 10 Feb 2021

Researchers create bone replicas using a hot nano-chisel

A holy grail for orthopedic research is a method for not only creating artificial bone tissue that precisely matches the real thing, but does so in such microscopic detail that it includes tiny structures potentially important for stem cell differentiation, which is key to bone regeneration.

9 Feb 2021

$Skeletal age calculator aims to better identify individuals at risk of bone fractures$

Skeletal age calculator aims to better identify individuals at risk of bone fractures

Researchers at the Garvan Institute of Medical Research have developed a computational model to calculate 'skeletal age', a personalized estimate of an individual's risk of bone fracture and premature death.

9 Feb 2021

Study reveals a novel role for Smurf2 protein in regulating bone formation

Bone morphogenetic protein (BMP) has a strong osteogenic (bone forming) ability. BMP has already been clinically applied to spinal fusion and non-union fractures.

8 Feb 2021

Novel hybrid device to boost research on metastatic process of breast cancer cells

European researchers are working on a novel hybrid device to better understand the metastatic process of cancer cells travelling from breast to bone and fast screen new drugs against it.

6 Feb 2021

$FDA approves cell-based gene therapy to treat adults with relapsed or refractory large-B-cell lymphoma$

FDA approves cell-based gene therapy to treat adults with relapsed or refractory large-B-cell lymphoma

Today, the U.S. Food and Drug Administration approved Breyanzi (lisocabtagene maraleucel), a cell-based gene therapy to treat adult patients with certain types of large B-cell lymphoma who have not responded to, or who have relapsed after, at least two other types of systemic treatment.

5 Feb 2021

Research shows how air pollution has a detrimental impact on cardiovascular health

Tiny particles of air pollution -- called fine particulate matter -- can have a range of effects on health, and exposure to high levels is a known risk factor for cardiovascular disease.

4 Feb 2021

Alzheimer's risk gene can increase COVID-19 susceptibility and severity

A City of Hope-led research team found that the same gene that increases the risk for Alzheimer's disease, ApoE4, can increase the susceptibility to and severity of COVID-19.

4 Feb 2021

Insight into role of aging in response to SARS-CoV-2 infection

Researchers at the University of California, Irvine set out to determine the differences between young people and older adults regarding their host responses against SARS-CoV-2. The team revealed that independent of disease severity, COVID-19 was linked to a significant shift in plasma inflammatory factors. The research is posted to the pre-print server medRxiv*.

3 Feb 2021

Oxysterol derivatives show powerful antiviral activity against SARS-CoV-2 in vitro

A new study describes the antiviral activity of oxysterols, or oxidized cholesterol derivatives, against SARS-CoV-2. These occur in nature, and are not only involved in lipid signaling pathways that modulate a host of processes within the body, including the immune response and lipid homeostasis.

3 Feb 2021

Bone News and Research

Big data can help assess risk prediction for osteoporosis, fractures

Study: Aspirin should be favored to prevent blood clots in children after complex heart surgery

Study reveals mechanisms behind sensitivity of multiple myeloma cells to EZH2 inhibition

FDA approves drug to reduce frequency of chemotherapy-induced bone marrow suppression

Scientists conduct interdisciplinary study on using nanoparticles to fight leukemia

STING activation may be a new approach to reduce graft-versus-host disease

Study offers a new way to treat children with bow hunter syndrome

Partial replacement of animal proteins with plant proteins increases bone formation in adults

Single strain of bacteria may reduce the severity of graft-versus-host disease

Study provides new insights into the mechanism of bone marrow tissue

Nature Inspired Materials

Researchers create bone replicas using a hot nano-chisel

Skeletal age calculator aims to better identify individuals at risk of bone fractures

Study reveals a novel role for Smurf2 protein in regulating bone formation

Novel hybrid device to boost research on metastatic process of breast cancer cells

FDA approves cell-based gene therapy to treat adults with relapsed or refractory large-B-cell lymphoma

Research shows how air pollution has a detrimental impact on cardiovascular health

Alzheimer's risk gene can increase COVID-19 susceptibility and severity

Insight into role of aging in response to SARS-CoV-2 infection

Oxysterol derivatives show powerful antiviral activity against SARS-CoV-2 in vitro

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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