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Scientists develop new class of drugs to treat hereditary kidney disease

Scientists from the University of Sheffield are part of an international collaboration to develop a new class of drugs to treat a common genetic kidney disease which is a major cause of kidney failure.

18 Jun 2019

Harvard chemists achieve landmark in drug discovery with synthesis of potent anti-cancer agent

It's a feat three decades in the making: Harvard University chemists have achieved what a new paper calls a "landmark in drug discovery" with the total synthesis of halichondrin.

17 Jun 2019

New natural extract inhibits the development of diabetic nephropathy

A team of researchers have published in the Journal of Cellular Physiology that a new natural extract is able to inhibit the development of diabetic nephropathy, a kidney disease that is increasing in incidence throughout the world.

16 Jun 2019

Super-Resolution Raman Imaging with Plasmonic Substrates

Renee Frontiera discusses the development of a super-resolution Raman microscope that could one day supersede fluorescence-based super-resolution microscopes.

From Pittcon 14 Jun 2019

New small drug-targeting molecules may improve cancer treatment

Researchers from the University of Notre Dame have developed small drug-targeting molecules that may be hundreds to thousands of times more effective at delivering potent drugs to desired sites of disease, including cancer.

14 Jun 2019

Disease-modifying therapy for Alport syndrome still remains an unmet need

Alport syndrome is a hereditary type IV collagen disease that leads to progressive proteinuria, renal fibrosis, and kidney failure.

13 Jun 2019

Tetrodotoxin found in pufferfish can provide potent pain relief when given properly

Opioids remain a mainstay of treatment for chronic and surgical pain, despite their side effects and risk for addiction and overdose.

13 Jun 2019

Scientists discover weakness in common cold virus

Scientists have discovered a weakness on the surface of the viruses that cause a multitude of illnesses.

12 Jun 2019

Boehringer Ingelheim and University of Dundee extend collaboration to develop new cancer medicines

Following the success of their ongoing alliance, Boehringer Ingelheim and the University of Dundee extend their collaboration to develop new medicines that target and destroy key cancer causing proteins.

12 Jun 2019

Scorpion venom contains compounds that could help fight Staph and tuberculosis bacteria

Researchers at Stanford University and Universidad Nacional Autónoma de México (UNAM) have found that a scorpion found in Eastern Mexico has a venom that could have antibacterial properties.

10 Jun 2019

Proteasome inhibitors show potential for combating multidrug-resistant malaria

Proteasome inhibitors have significant promise as components of novel combination therapies to treat multidrug-resistant malaria, according to a study published June 6 in the open-access journal PLOS Pathogens by David Fidock, Caroline Ng, and Barbara Stokes of Columbia University Irving Medical Center, Matthew Bogyo of Stanford University School of Medicine, and colleagues.

From PLOS ONE 10 Jun 2019

Study offers hope to slow down or prevent progression of Parkinson’s

Results from a study published today looking at a molecule targeting clumps of alpha-synuclein, a key protein linked to Parkinson’s, offers hope that it may be possible to slow down or prevent the progression of the condition in humans.

6 Jun 2019

Bioactive hydrogel promises faster wound healing

A new study published in the journal 'Science Advances' presents the use of a novel tissue engineering material composed of bioactive injectable hydrogel to speed up the rate of healing in wounded tissues.

6 Jun 2019

Research on cannabis use in women limited, finds new study

A new study from the University of York shows that research into the association of psychosis with cannabis focuses almost completely on men users, significantly limiting our knowledge of the drug’s effects on human health.

5 Jun 2019

Researchers investigate how antibiotic produced by the microbiome kills bacteria

A research team from the Universities of Tübingen and Göttingen as well as from the German Center for Infection Research has investigated the mode of action of a new class of antibiotics that is highly effective against multidrug-resistant pathogens.

4 Jun 2019

Reversing drug resistance in tuberculosis bacteria

About 1.5 million people died of tuberculosis (TB) in 2017, making it the most lethal infectious disease worldwide. A growing rise in drug-resistant TB is a major obstacle to successfully treating the illness.

4 Jun 2019

Lithium improves muscle size and strength in mice with limb girdle muscular dystrophy

Standing up from a chair, climbing stairs, brushing one's hair - all can be a struggle for people with a rare form of muscular dystrophy that causes progressive weakness in the shoulders and hips. Over time, many such people lose the ability to walk or to lift their arms above their heads.

3 Jun 2019

African rodents immune to pain caused by wasabi

A new report in Science provides the first evidence of a mammal - the highveld mole-rat - being immune to pain from exposure to allyl isothiocyanate, or AITC, the active ingredient of wasabi.

31 May 2019

International research collaboration uses FDA-approved drugs to slow aging in nematodes

An international research collaboration that includes the University of Arkansas for Medical Sciences has discovered that aging in nematodes (worms) can be slowed and even reversed by a number of Food and Drug Administration-approved drugs, findings that have the potential to extend human lifespan.

30 May 2019

New fluorescent probe specifically labels microglia cells

Part of the immune system in the brain is made up of so-called microglia cells. Korean and Singaporean researchers have now developed a fluorescent probe that specifically labels this type of macrophage. The cells were visualized in cell culture and in the live brains of rodents.

29 May 2019