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Study examines how food additive MSG contributes to obesity and liver disease

The commonly used food additive monosodium glutamate (MSG) has been linked to obesity and disorders associated with the metabolic syndrome including progressive liver disease.

28 May 2014

Hospitals sue HHS over lengthy RAC appeals

The hospitals are demanding the agency fulfill its requirement to decide Medicare payment appeals within 90 days, instead of the current 16-month average.

28 May 2014

Genetic variant linked to sudden cardiac death leads to protein overproduction in heart cells

A genetic variant linked to sudden cardiac death leads to protein overproduction in heart cells, Johns Hopkins scientists report. Unlike many known disease-linked variants, this one lies not in a gene but in so-called noncoding DNA, a growing focus of disease research.

28 May 2014

Findings may help medical researchers identify effective drug targets for triple negative breast cancer

The suppression of two genes reduce breast cancer tumor formation and metastasis by interfering with blood vessel formation and recruitment, report scientists from Houston Methodist and five other institutions in the Proceedings of the National Academy of Sciences (now online).

28 May 2014

Study identifies role of additive monosodium glutamate in obesity and liver disease

The commonly used food additive monosodium glutamate (MSG) has been linked to obesity and disorders associated with the metabolic syndrome including progressive liver disease.

28 May 2014

Case Western Reserve physician calls on FDA to address hidden risk of dangerous drugs side effects

The agency charged to protect patients from dangerous drug side effects needs to be far more vigilant when it comes to medications that affect blood pressure.

28 May 2014

Half-life extension technology: an interview with Dermot Pearson, Novozymes Biopharma

A drug's half-life indicates how long a substance will remain active in the body. It is essentially the period of time that it takes for the concentration of the amount of the drug to be reduced by half, and therefore, determines how frequently a drug needs to be administered to maintain its therapeutic effect.

27 May 2014

Scientists find interplay between two specific proteins crucial for flawless repair of crosslink damage

Environmental influences such as ionizing radiation, intense heat or various chemical substances damage the DNA constantly.

27 May 2014

Inovio announces positive results on DNA-based monoclonal antibody therapy targeting CHIKV

Inovio Pharmaceuticals, Inc. announced today that its novel DNA-based therapeutic monoclonal antibody targeting Chikungunya virus (CHIKV) completely protected mice from a lethal CHIKV challenge.

27 May 2014

Alligator Bioscience acquires rights to drug development candidate ADC-1013

BioInvent International AB (publ) (OMXS:BINV) today announced that the company has sold back all its rights to drug development candidate ADC-1013 to former partner Alligator Bioscience for an undisclosed sum.

27 May 2014

Study reveals high demand for costly cancer treatment among refugees from Iraq, Syria

A study published in The Lancet Oncology journal reveals a high demand for costly cancer treatment among refugees from the recent conflicts in Iraq and Syria, with host countries struggling to find the money and the medicine to treat their new patients.

26 May 2014

Researchers discover novel enzyme that promotes insulin secretion in type 2 diabetes animal model

A signal that promotes insulin secretion and reduces hyperglycemia in a type 2 diabetes animal model is enhanced by the inhibition of a novel enzyme discovered by CHUM Research Centre (CRCHUM) and University of Montreal researchers.

26 May 2014

Peptide antibodies hit immune-response-stifling MDSCs without harming other vital cells

Scientists have found a way to target elusive cells that suppress immune response, depleting them with peptides that spare other important cells and shrink tumors in preclinical experiments, according to a paper published online by Nature Medicine.

26 May 2014

Longer looks: How doctors treat patients; myths about Obamacare; curing cancer

Many years ago I spent a lunch hour in a doctors' dining room eavesdropping on two white-coated men of a certain age idly discussing a colleague who worked at the city hospital next door.

23 May 2014

First Edition: May 23, 2014

Today's early morning highlights from the major news organizations, including the latest developments on the Department of Veterans Affairs controversy.

23 May 2014

EMA's CHMP gives positive opinion for PTC Therapeutics' Translarna

PTC Therapeutics, Inc. today announced that following its request for re-examination, the Committee for Medicinal Products for Human Use of the European Medicines Agency has adopted a positive opinion regarding the company's application for a conditional marketing authorization of Translarna (ataluren) for the treatment of nonsense mutation Duchenne muscular dystrophy (nmDMD) in ambulatory patients aged five years and older.

23 May 2014

World Health Assembly approves resolution on viral hepatitis and noncommunicable diseases

The World Health Assembly approved a resolution to improve the prevention, diagnosis and treatment of viral hepatitis and proposals to improve global coordination of efforts to address noncommunicable diseases like diabetes, cancers, heart disease and stroke. In addition, WHO's Director-General and the President of the Health Assembly presented 4 awards to leaders in public health.

23 May 2014

Researchers identify chemical signals that promote breast cancer metastasis

Working with mice, Johns Hopkins researchers report they have identified chemical signals that certain breast cancers use to recruit two types of normal cells needed for the cancers' spread.

23 May 2014

Victims who are repeatedly assaulted show greater levels of psycho-behavioral consequences

According to recent studies, one in five adult women and one in 100 adult men have reported being raped. The prevalence increases to two in five among women and one in five among men who report experiencing other forms of sexual violence, such as repeated unwanted sexual contact and sexual coercion.

23 May 2014

Analysis of key cellular protein demonstrates the effectiveness of Taxol anti-cancer drug

A pathway to the design of even more effective versions of the powerful anti-cancer drug Taxol has been opened with the most detailed look ever at the assembly and disassembly of microtubules, tiny fibers of tubulin protein that form the cytoskeletons of living cells and play a crucial role in mitosis.

23 May 2014

Drugs News and Research

Study examines how food additive MSG contributes to obesity and liver disease

Hospitals sue HHS over lengthy RAC appeals

Genetic variant linked to sudden cardiac death leads to protein overproduction in heart cells

Findings may help medical researchers identify effective drug targets for triple negative breast cancer

Study identifies role of additive monosodium glutamate in obesity and liver disease

Case Western Reserve physician calls on FDA to address hidden risk of dangerous drugs side effects

Half-life extension technology: an interview with Dermot Pearson, Novozymes Biopharma

Scientists find interplay between two specific proteins crucial for flawless repair of crosslink damage

Inovio announces positive results on DNA-based monoclonal antibody therapy targeting CHIKV

Alligator Bioscience acquires rights to drug development candidate ADC-1013

Study reveals high demand for costly cancer treatment among refugees from Iraq, Syria

Researchers discover novel enzyme that promotes insulin secretion in type 2 diabetes animal model

Peptide antibodies hit immune-response-stifling MDSCs without harming other vital cells

Longer looks: How doctors treat patients; myths about Obamacare; curing cancer

First Edition: May 23, 2014

EMA's CHMP gives positive opinion for PTC Therapeutics' Translarna

World Health Assembly approves resolution on viral hepatitis and noncommunicable diseases

Researchers identify chemical signals that promote breast cancer metastasis

Victims who are repeatedly assaulted show greater levels of psycho-behavioral consequences

Analysis of key cellular protein demonstrates the effectiveness of Taxol anti-cancer drug

Industry Focus eBook - Cell biology (5th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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