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Oxygen-starved tumors have an Achilles' heel that could be targeted with drugs

A tumor's goal is simple: to grow, grow, grow, by making more cancer cells. But that often means growing so fast that the oxygen supply gets scarce, at which point cells within the tumor start to suffocate.

25 Jun 2018

Researchers discover immune profile for effective cancer immunotherapy

In a new study published online June 25, 2018 in Nature Medicine, UC San Francisco researchers have identified a key biological pathway in human cancer patients that appears to prime the immune system for a successful response to immunotherapy drugs known as checkpoint inhibitors.

25 Jun 2018

New discovery suggests potential target for treating cancers and other diseases

When cells grow and divide to ensure a biological function - such as a properly working organ - DNA must be unwound from its typical tightly packed form and copied into RNA to create proteins.

25 Jun 2018

Cedars-Sinai launches new initiative to improve treatments for gastrointestinal, metabolic diseases

Cedars-Sinai has launched an initiative to accelerate the development of novel drugs, devices and therapies aimed at improving treatments for patients with gastrointestinal and metabolic diseases.

25 Jun 2018

Lund researchers develop fluorescent variant of a molecule that inhibits cancer stem cells

A team of researchers at Lund University in Sweden has developed a fluorescent variant of a molecule that inhibits cancer stem cells.

25 Jun 2018

Researchers use gene editing to reduce autism symptoms in mice

Researchers have used CRISPR-Cas9 gene editing to treat symptoms of autism in mice. It is hoped that the tool could one day be used to help humans.

25 Jun 2018

ABPI associated with NHS for 70 years in pharmaceutical research

In this special year, both the NHS and the Association of the British Pharmaceutical Industry are celebrating our respective 70th anniversaries. The histories of these two organizations have been inextricably linked since 1948 and our relationship with the NHS continues to go from strength to strength.

25 Jun 2018

Studying The Effects of Microgravity on Muscle Mass

Studying the effects of gravity on muscle cells can give us an insight into muscle wastage diseases, and potentially guide the development of new therapies. Professor Louis Yuge discusses his research and the cellular changes that occur in response to microgravity.

25 Jun 2018

Novel approach to visualize how platelets are formed in body

Platelets are uniquely mammalian cells, and are the small cells of the blood that are critical for us to stop bleeding when we cut ourselves.

25 Jun 2018

Newly developed model of retina can predict outcome of perturbation with high precision

Our eye hosts a powerful biological computer, the retina. Understanding how the retina transforms images from the outside world into signals that the brain can interpret would not only result in insights into brain computations, but could also be useful for medicine.

25 Jun 2018

Coffee and the heart – four strong cups a day is beneficial finds study

According to a new study four cups of strong coffee might be the amount that would keep the hearts of older adults healthy. The latest study titled, “CDKN1B/p27 is localized in mitochondria and improves respiration-dependent processes in the cardiovascular system—New mode of action for caffeine,” was published on 21st of June 2018 in the journal PLOS Biology.

25 Jun 2018

DNA patterns in circulating blood cells can help identify spastic cerebral palsy

A Delaware team including Erin Crowgey, PhD, associate director of Bioinformatics with Nemours Biomedical Research, has published a study in the peer-reviewed journal BMC Bioinformatics, showing that DNA patterns in circulating blood cells can be used to help identify spastic cerebral palsy (CP) patients.

22 Jun 2018

Study: Broken shuttle protein may hinder learning in patients with brain disorders

Unable to carry signals based on sights and sounds to the genes that record memories, a broken shuttle protein may hinder learning in patients with intellectual disability, schizophrenia, and autism.

22 Jun 2018

Researchers discover drug compound that inhibits movement of cancer cells

Fighting cancer means killing cancer cells. However, oncologists know that it's also important to halt the movement of cancer cells before they spread throughout the body.

22 Jun 2018

Scientists develop new device to test cancer drug combinations quickly and cheaply

Combinations of cancer drugs can be quickly and cheaply tested on tumor cells using a novel device developed by EMBL scientists

22 Jun 2018

Study: Inner nuclear envelope plays role in lipid metabolism

The cell nucleus is an organelle, in which the DNA of an organism is protected and duplicated. The nucleus of this organ-like structure in the cell plasma is surrounded by an outer and an inner nuclear envelope, which is penetrated by openings - so-called nuclear pores.

22 Jun 2018

Unusual cell-to-cell communication in glioblastoma promotes aggressiveness and therapy resistance

A surprising form of cell-to-cell communication in glioblastoma promotes global changes in recipient cells, including aggressiveness, motility, and resistance to radiation or chemotherapy.

22 Jun 2018

Four cups of coffee a day shown to protect heart muscle

A new study has shown that drinking four cups of coffee a day can protect against heart muscle damage, through the effect of caffeine on a protein called p27.

22 Jun 2018

Researchers diagnose cerebral palsy using AI and next-generation sequencing

Researchers have shown that patients with spastic cerebral palsy (CP) can be identified using DNA methylation patterns in circulating blood cells.

22 Jun 2018

CellGenix completes first phase of facility expansion to meet rising demands for GMP cell culture reagents

CellGenix, a global manufacturing leader of GMP-grade raw materials for cell therapy, gene therapy and tissue-engineered products, successfully completed the first phase of its headquarters’ expansion as more customers approach late-stage clinical development and commercialization.

22 Jun 2018

B Cell News and Research

Oxygen-starved tumors have an Achilles' heel that could be targeted with drugs

Researchers discover immune profile for effective cancer immunotherapy

New discovery suggests potential target for treating cancers and other diseases

Cedars-Sinai launches new initiative to improve treatments for gastrointestinal, metabolic diseases

Lund researchers develop fluorescent variant of a molecule that inhibits cancer stem cells

Researchers use gene editing to reduce autism symptoms in mice

ABPI associated with NHS for 70 years in pharmaceutical research

Studying The Effects of Microgravity on Muscle Mass

Novel approach to visualize how platelets are formed in body

Newly developed model of retina can predict outcome of perturbation with high precision

Coffee and the heart – four strong cups a day is beneficial finds study

DNA patterns in circulating blood cells can help identify spastic cerebral palsy

Study: Broken shuttle protein may hinder learning in patients with brain disorders

Researchers discover drug compound that inhibits movement of cancer cells

Scientists develop new device to test cancer drug combinations quickly and cheaply

Study: Inner nuclear envelope plays role in lipid metabolism

Unusual cell-to-cell communication in glioblastoma promotes aggressiveness and therapy resistance

Four cups of coffee a day shown to protect heart muscle

Researchers diagnose cerebral palsy using AI and next-generation sequencing

CellGenix completes first phase of facility expansion to meet rising demands for GMP cell culture reagents

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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