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Study provides clues to how cancer cells develop resistance to chemotherapies

About half of all drugs, ranging from morphine to penicillin, come from compounds that are from - or have been derived from - nature. This includes many cancer drugs, which are toxic enough to kill cancer cells.

22 Jun 2018

Researchers outline a connection between subplate neurons and brain disorders

The disappearance of an entire brain region should be cause for concern. Yet, for decades scientists have calmly maintained that one brain area, the subplate, simply vanishes during the course of human development.

22 Jun 2018

New study reveals how ‘good’ bacteria help in regulating our metabolism

Research tells us that the commensal or "good" bacteria that inhabit our intestines help to regulate our metabolism.

22 Jun 2018

Study reveals how mTORC1-driven changes in crowding could influence major diseases

Among the most studied protein machines in history, mTORC1 has long been known to sense whether a cell has enough energy to build the proteins it needs to multiply as part of growth.

22 Jun 2018

Scientists identify gene that triggers senescence

Scientists seeking to unlock the secrets of cellular aging have identified a gene that triggers senescence, a phenomenon in which cells stop dividing.

22 Jun 2018

Researchers discover new type of cell that hinders formation of fat cells

Obesity is the plague of our times. Some 80 percent of obese people will develop Type 2 diabetes at some point in their lives, and being overweight is also a significant risk factor for cancer and heart attacks.

22 Jun 2018

Lipid-scrambling DNA enzyme outperforms naturally occurring counterpart, say researchers

A new synthetic enzyme, crafted from DNA rather than protein, flips lipid molecules within the cell membrane, triggering a signal pathway that could be harnessed to induce cell death in cancer cells.

22 Jun 2018

Novel cellular pathway may clarify how arterial inflammation develops into atherosclerosis

Investigators have identified a new cellular pathway that may help explain how arterial inflammation develops into atherosclerosis - deposits of cholesterol, fats and other substances that create plaque, clog arteries and promote heart attacks and stroke. The findings could lead to improved therapies for atherosclerosis, a leading cause of death worldwide.

22 Jun 2018

Jumping genes or transposons and their role in the genetic code

Researchers have found that there a numerous transposons or “jumping genes” within the genetic code that is responsible for development of the embryo and its growth. These were earlier thought to be junk or useless parts of the genome.

22 Jun 2018

The GW Cancer Center expands bone marrow transplant and cell therapies

The George Washington University (GW) Cancer Center is pleased to welcome a team of internationally-recognized experts who together will lead the expanded Bone Marrow Transplant and Cell Therapies Program.

22 Jun 2018

Herpes may play role in pathogenesis of Alzheimer’s

Herpes virus present within the body long after the overt infection may play a role in the pathogenesis of Alzheimer’s disease say researchers. The study titled, “Multiscale Analysis of Independent Alzheimer’s Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus” appeared in the latest issue of the journal Neuron, this Thursday.

22 Jun 2018

Research does not confirm antidiabetic action of natural fatty acid derivatives

A research consortium between the healthcare company Sanofi and Johannes Gutenberg University Mainz investigated the antidiabetic action of certain natural fatty acids, so-called FAHFAs, which US-American scientists had reported in 2014.

21 Jun 2018

UC Riverside researcher receives grants to advance cancer, ALS research

Maurizio Pellecchia, who holds the Daniel Hays Chair in Cancer Research at the University of California, Riverside, has received two grants to continue his research aimed at finding therapeutics for cancer, amyotrophic lateral sclerosis, and other neurodegenerative diseases.

21 Jun 2018

Study reveals new target to halt tumor growth

Researchers at the University of Wisconsin-Madison have discovered that a protein called Munc13-4 helps cancer cells secrete large numbers of exosomes - tiny, membrane-bound packages containing proteins and RNAs that stimulate tumor progression.

21 Jun 2018

Scientists discover the molecular trigger of necroptosis

Researchers have uncovered a trigger for an immune-related cell death pathway called necroptosis. The discovery could be used to develop new treatments for cancer and immune disorders.

21 Jun 2018

Protein Data Bank at Rutgers impacts research, education and drug discovery

When Jimmy Carter was diagnosed with end-stage metastatic melanoma in 2015, he began taking a drug developed in part using 3D molecular data.

21 Jun 2018

Breakthrough discovery reveals brain metals that may drive progression of Alzheimer’s disease

Alzheimer's disease could be better treated, thanks to a breakthrough discovery of the properties of the metals in the brain involved in the progression of the neurodegenerative condition, by an international research collaboration including the University of Warwick.

21 Jun 2018

Study finds cell-free DNA profiling as versatile method to monitor UTIs

Using shotgun DNA sequencing, Cornell University researchers have demonstrated a new method for monitoring urinary tract infections that surpasses traditional methods in providing valuable information about the dynamics of the infection as well as the patient's biological response.

21 Jun 2018

USC study reveals how the cell launches emergency response to repair damaged DNA

The cell has its own paramedic team and emergency room to aid and repair damaged DNA, a new USC Dornsife study reveals.

21 Jun 2018

New guidelines recommend newborns with Down’s syndrome to receive leukemia test

New genetic testing has been developed at the University of Oxford to detect early signs of a potentially fatal condition that can also develop into full blown leukaemia in children with Down’s syndrome.

21 Jun 2018