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New intervention program may benefit chronically homeless, alcohol-dependent individuals

Chronically homeless, alcohol-dependent individuals might benefit from a new intervention that does not require them to stop or even reduce drinking, according to the results of a preliminary study in Seattle.

16 May 2014

New dual-pronged approach for treating Niemann-Pick type C disease

By studying nerve and liver cells grown from patient-derived induced pluripotent stem cells (iPSCs), Whitehead Institute researchers have identified a potential dual-pronged approach to treating Niemann-Pick type C (NPC) disease, a rare but devastating genetic disorder.

16 May 2014

UH pharmacy students earn awards for excellence in leadership, professional service and clinical skills from TSHP

University of Houston (UH) pharmacy students wrapped up the spring semester with a round of awards for excellence in leadership, professional service and clinical skills.

16 May 2014

CHOP oncologist receives Lifetime Achievement Award at ANRA association's international meeting

The Advances in Neuroblastoma Research Association (ANRA) is conferring its highest honor on pediatric oncologist Garrett M. Brodeur, M.D., of the Cancer Center at The Children's Hospital of Philadelphia (CHOP).

16 May 2014

Researchers test genomic sequencing for women with triple negative breast cancer

Indiana University cancer researchers are testing whether therapy incorporating advanced genomic technology will provide better outcomes than current treatments for those with an aggressive form of breast cancer.

15 May 2014

New tech could take light-based cancer treatment deep inside the body

Photodynamic therapy (PDT) is an effective treatment for easily accessible tumors such as oral and skin cancer.

15 May 2014

A potential epigenetic 'on-off' switch for cancer

A team of Boston University School of Medicine (BUSM) researchers have proposed that an "on and off" epigenetic switch could be a common mechanism behind the development of different types of cancer. Epigenetics is the phenomena whereby genetically identical cells express their genes differently, resulting in different physical traits.

15 May 2014

Study: Lorazepam drug not effective in treating pediatric status epilepticus

A National Institutes of Health-sponsored study published in the Journal of the American Medical Association showed that lorazepam - a widely used but not yet Food and Drug Administration approved drug for children - is no more effective than an approved benzodiazepine, diazepam, for treating pediatric status epilepticus.

15 May 2014

Isis Pharmaceuticals receives $3 million milestone payment from GSK

Isis Pharmaceuticals, Inc. announced today that it has earned a $3.0 million milestone payment from GlaxoSmithKline (GSK) related to the initiation of a natural history study, which will support the advancement of one of the alliance programs.

15 May 2014

Novel targeted drug shows promise in treating patients with advanced pigmented villonodular synovitis

A novel targeted drug shows promise in treating patients with advanced pigmented villonodular synovitis (PVNS), a rare neoplastic joint disorder, according to new phase I data from Memorial Sloan Kettering Cancer Center and other institutions highlighted to media today in advance of the 50th Annual Meeting of the American Society of Clinical Oncology (ASCO), which will take place from May 30 to June 3 in Chicago.

15 May 2014

Suppressing hyperactivity of calcium channels alleviates familial Alzheimer's disease

In 2008, researchers at the Perelman School of Medicine at the University of Pennsylvania showed that mutations in two proteins associated with familial Alzheimer's disease (FAD) disrupt the flow of calcium ions within neurons.

15 May 2014

Study: Wider use of medications may help reduce substance abuse, related hospital admissions

A comparatively new form of a medication for alcohol and opioid dependence that's injected once a month instead of taken orally once a day appears to be significantly more effective than some other medications - because more patients actually continue the prescribed regimen.

15 May 2014

Antidepressant stops growth of plaques in mouse model of Alzheimer's disease

A commonly prescribed antidepressant can reduce production of the main ingredient in Alzheimer's brain plaques, according to new research at Washington University School of Medicine in St. Louis and the University of Pennsylvania.

15 May 2014

Investigators find effective treatment for life-threatening angioedema attacks in ED

Investigators at the University of Cincinnati have found a safe and effective treatment for life-threatening angioedema attacks in the emergency department.

15 May 2014

Antipsychotic use linked to reduced patient violence

Prescribing antipsychotics may reduce psychiatric patients’ propensity to commit violent crime, a study in The Lancet suggests.

14 May 2014

‘Lessebo’ effect implications for Parkinson’s therapies

Patients with Parkinson’s disease have a reduced objective response to treatment given in a clinical trial if they know they may be taking a placebo, research shows.

14 May 2014

Retrophin reports net loss of $70.6 million for first quarter 2014

Retrophin, Inc. today reported its financial results for the quarter ended March 31, 2014.

14 May 2014

Isis Pharmaceuticals reports positive data from ISIS-GCGRRx Phase 2 study in patients with type 2 diabetes

Isis Pharmaceuticals, Inc. announced today positive data from a Phase 2 study of ISIS-GCGRRx in patients with type 2 diabetes uncontrolled on stable metformin therapy.

14 May 2014

Aradigm reports total revenue of $6.6 million for Q1 2014

Aradigm Corporation today announced financial results for the first quarter and three months ended March 31, 2014.

14 May 2014

Viewpoints: What's next for employer mandate; SCOTUS and retiree health plans; the 'next big issue'

As complaints and cavils about the Affordable Care Act fall by the wayside, one piece of the law looms ever larger as its most controversial element: the employer mandate, which in 2016 will impose a penalty on businesses with 50 to 99 employees for not offering them health coverage (Michael Hiltzik, 5/12).

14 May 2014

Drugs News and Research

New intervention program may benefit chronically homeless, alcohol-dependent individuals

New dual-pronged approach for treating Niemann-Pick type C disease

UH pharmacy students earn awards for excellence in leadership, professional service and clinical skills from TSHP

CHOP oncologist receives Lifetime Achievement Award at ANRA association's international meeting

Researchers test genomic sequencing for women with triple negative breast cancer

New tech could take light-based cancer treatment deep inside the body

A potential epigenetic 'on-off' switch for cancer

Study: Lorazepam drug not effective in treating pediatric status epilepticus

Isis Pharmaceuticals receives $3 million milestone payment from GSK

Novel targeted drug shows promise in treating patients with advanced pigmented villonodular synovitis

Suppressing hyperactivity of calcium channels alleviates familial Alzheimer's disease

Study: Wider use of medications may help reduce substance abuse, related hospital admissions

Antidepressant stops growth of plaques in mouse model of Alzheimer's disease

Investigators find effective treatment for life-threatening angioedema attacks in ED

Antipsychotic use linked to reduced patient violence

‘Lessebo’ effect implications for Parkinson’s therapies

Retrophin reports net loss of $70.6 million for first quarter 2014

Isis Pharmaceuticals reports positive data from ISIS-GCGRRx Phase 2 study in patients with type 2 diabetes

Aradigm reports total revenue of $6.6 million for Q1 2014

Viewpoints: What's next for employer mandate; SCOTUS and retiree health plans; the 'next big issue'

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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