Genes News and Research

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Disruption of a single gene, Nrf2, plays a critical role in determining the susceptibility to asthma

A research team led by Shyam Biswal , PhD, at the Johns Hopkins Bloomberg School of Public Health found the absence of Nrf2 exacerbated allergen-mediated asthma in mice models.

5 Jul 2005

DNA imaging suggests where lung cancer genes may reside

With equipment designed to probe the smallest segments of the genetic code, researchers at Dana-Farber Cancer Institute and collaborating institutions have found sections of the chromosomes of lung cancer cells where cancer-related genes may lurk.

4 Jul 2005

Potatoes found to help reduce blood pressure and other diseases

UK scientists have identified bioactive plant chemicals in the most practical of staple foods, the potato. These natural chemicals have been associated with reduced blood pressure and they selectively affect a chemotherapeutic target for trypanosomes and similar diseases such as sleeping sickness.

30 Jun 2005

Scientists discover identifying markers for primitive blood-forming stem cells - simplifies cell identification

Scientists at the University of Michigan Medical School have discovered the biological equivalent of a grocery store bar code on the surface of primitive, blood-forming stem cells in mice. Called hematopoietic stem cells, they give rise to all the different types of specialized cells found in blood.

30 Jun 2005

Protein that was thought to simply turn genes on and off now looks to be more like a cellular dimmer switch

The scientists showed for the first time that when certain parts of a protein molecule are modified - flexible, randomly structured regions believed to be only minor players in the protein world - they become important in turning genes on and off, but in a way that resembles a dimmer switch rather than an on-off switch.

30 Jun 2005

Map of gene control regions provides tool for understanding cells' different roles

In another step to decipher information in the human genome, scientists have discovered the location and sequence of over 10,000 DNA regions that function as genetic on-off switches, or "promoters" in human fibroblasts.

29 Jun 2005

Saturated fats combined with genetic trait may make people more susceptible to type 2 diabetes

A University of Alberta team of researchers has discovered an additional 2 million Canadians who have a high fat diet or are overweight may be at increased risk for developing type 2 diabetes if they carry a particular type of common specific genetic trait known as a polymorphism.

29 Jun 2005

Exercise helps find genetic regions linked to prediabetes

People's bodies respond to exercise in different ways, and their genetic makeup is partly responsible.

28 Jun 2005

Multi-million pound Grand Challenge grants to tackle TB and malaria in the developing world

UK scientists are to help tackle TB and malaria in the developing world through their leadership of two major international research projects.

28 Jun 2005

New clues about the location of genes potentially involved in the most common type of lung cancer

Using technology that makes it possible to zoom in on smaller sections of cell chromosomes than ever before, researchers at Dana-Farber Cancer Institute have identified nearly 100 chromosome regions where genes are either over-copied or missing in non-small cell lung cancer.

27 Jun 2005

Technique called phylogenetic footprinting reveals new gene regulation system

By comparing 140 sequenced bacterial genomes, researchers have uncovered a system for regulating genes essential to bacterial replication - and they did it solely by computer keystrokes and mouse clicks.

27 Jun 2005

New research raises the possibility that the risk of developing arsenic-related disease is not the same for everybody

Children with a particular variation in the CYT19 gene metabolize arsenic differently than adults with the same genetic variant, according to a new research report. The findings have important implications for the safety of drinking water worldwide and the use of arsenic as a cancer drug.

27 Jun 2005

Expression profiles and functional analyses of Wnt-related genes in human joint disorders

The cellular signaling protein Wnt, which is involved in embryonic development and cancer, contributes to disease progression of both rheumatoid arthritis and osteoarthritis.

26 Jun 2005

WHO wants more safety checks on genetically-modified food

In a recent report, the World Health Organization (WHO), has reiterated its view about the general safety of GMO foods. It also says that though genetically-modified organisms (GMO) can raise crop yields and food quality, which ultimately improves health and levels of nutrition as well as profits

26 Jun 2005

Special genes enable some women to give birth over the age of 45

A genetic advantage allows some women to give birth over the age of 45, say researchers.

22 Jun 2005

Folic acid improves memory and protects the brain from aging

According to scientists in Holland high doses of folic acid might help slow the cognitive decline of aging.

22 Jun 2005

AAV2 has great potential to be developed as an anti-cancer agent

Six days is all it takes for a common, non-disease-causing virus to kill cervical, breast, prostate and squamous cell cancer cells in laboratory cultures, according to Penn State College of Medicine researchers.

21 Jun 2005

Foxp2 gene plays an essential role in the development of social communication

The association between Foxp2 and language was first identified in a family in which half the members had severe speech and grammar impairments. Studies showed that all the affected family members had a mutation in the Foxp2 gene.

21 Jun 2005

PNNL ScalaBLAST may be used to process complex genomic sequences

A new computational tool developed at the Department of Energy's Pacific Northwest National Laboratory is speeding up our understanding of the machinery of life - bringing us one step closer to curing diseases, finding safer ways to clean the environment and protecting the country against biological threats.

21 Jun 2005

Researchers develop method that can help doctors choose the best combination of drugs for fighting cancer

The method is based on a mathematical model that determines when a cancer becomes drug-resistant during therapy. It does this by estimating the probability of finding drug-resistant mutant cells at different stages of cancer progression and examining the fate of individual mutant colonies during therapy.

21 Jun 2005

Genes News and Research

Disruption of a single gene, Nrf2, plays a critical role in determining the susceptibility to asthma

DNA imaging suggests where lung cancer genes may reside

Potatoes found to help reduce blood pressure and other diseases

Scientists discover identifying markers for primitive blood-forming stem cells - simplifies cell identification

Protein that was thought to simply turn genes on and off now looks to be more like a cellular dimmer switch

Map of gene control regions provides tool for understanding cells' different roles

Saturated fats combined with genetic trait may make people more susceptible to type 2 diabetes

Exercise helps find genetic regions linked to prediabetes

Multi-million pound Grand Challenge grants to tackle TB and malaria in the developing world

New clues about the location of genes potentially involved in the most common type of lung cancer

Technique called phylogenetic footprinting reveals new gene regulation system

New research raises the possibility that the risk of developing arsenic-related disease is not the same for everybody

Expression profiles and functional analyses of Wnt-related genes in human joint disorders

WHO wants more safety checks on genetically-modified food

Special genes enable some women to give birth over the age of 45

Folic acid improves memory and protects the brain from aging

AAV2 has great potential to be developed as an anti-cancer agent

Foxp2 gene plays an essential role in the development of social communication

PNNL ScalaBLAST may be used to process complex genomic sequences

Researchers develop method that can help doctors choose the best combination of drugs for fighting cancer

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